Podcast: Listen to Phoenix Leaders Share Insights about the Rising Bioindustry in the Nation’s 5th Largest City. Podcast: Listen to Phoenix Leaders Share Insights about the Rising Bioindustry in the Nation’s 5th Largest City. <div class="ExternalClass9619C5469924480CB1CEF66D8B4F0242"><html> Listen to conversations with Phoenix Mayor Kate Gallego and other leaders as they share their insights with Tom Osha, Senior Vice President of Innovation and Economic Development at Wexford Science+Technology, about Phoenix’s growing and thriving bioindustry ecosystem.<br><br>Listen to these conversations beginning June 8, 2020 <a href="https://wexfordscitech.com/thecommons/" target="_blank"><strong><em>here</em></strong></a>:<br><ul><li><strong>Episode 1 –</strong> <em>The Role of Innovation Districts in Restarting the Economy</em><br></li><li><strong>Episode 2 </strong>– <em>Arizona’s Life Sciences Roadmap</em><br></li><li><strong>Episode 3 </strong>– <em>Phoenix is HOT! And so is the Phoenix Biomedical Campus</em></li><li><strong>Episode 4 </strong>– <em>ASU #1 for Innovation</em></li><li><strong>Episode </strong><strong>5 </strong>– <em>A Fertile Environment for Start-Ups: The OncoMyx Story</em></li><li><strong>Episode </strong><strong>6 </strong>– <em>Building the Life Sciences Workforce</em></li><li><strong>Episode </strong><strong>7 </strong>– <em>The Wexford Knowledge Community</em></li></ul>Sparking collaboration is the purpose of the Phoenix bioindustry ecosystem. Phoenix, Arizona, where each day is a relentless pursuit of cures. From discovery to delivery, join Phoenix companies and the leading edge of personalized medicine. Come to a young, vibrant community in an environment where ideas thrive. With a lack of barriers to enter the market, America’s fastest-growing population, and an entrepreneurial pioneer spirit, this is the place for rising to success. Join Translational Genomics Research Institute, three research universities, and world class bioscientists on the Phoenix Biomedical Campus. Located in dynamic Downtown Phoenix, home to Wexford Science and Technology’s collaboration-designed bioscience research building, the Center for Entrepreneurial Innovation, and unlimited opportunities. Learn more at <a href="/" target="_blank"><strong>www.biomedicalphoenix.com</strong></a> and <a href="https://www.phoenix.gov/econdev/bio" target="_blank"><strong>www.phoenix.gov/econdev/bio</strong> </a> <p> <br> </p> </html></div>2021-01-19T07:00:00ZWexford
Event: Aging and the Arts new Health & Humanities SeriesEvent: Aging and the Arts new Health & Humanities Series<div class="ExternalClassA9F1D1D217A64E2BB405E06A2EA45130"><html>​<a style="background-color:window;font-family:inherit;font-size:10pt;" href="https://arizona.zoom.us/webinar/register/WN_CjuUCwpFQ0OxLVFM1nNb8A" target="_blank"><p style="display:inline !important;"><strong>Webinar Registration</strong></p></a><br><br><span id="ms-rterangepaste-start"></span>You're invited to the newly launched Health and Humanities series, <strong>Aging and the Arts</strong>. The Office of Engagement and Events at the University of Arizona Health Sciences is offering this free, live-streamed education and exercise series to promote better health and wellness for an aging population. These free sessions are open to the general public, and are especially beneficial to older adults.​<span id="ms-rterangepaste-end"></span><a href="https://arizona.zoom.us/webinar/register/WN_CjuUCwpFQ0OxLVFM1nNb8A" target="_blank"><br><p> <br> </p> <p> ​<br> </p> </a></html></div>https://biomedicalphoenix.com/Lists/News/Attachments/134/Aging and the Arts.png2021-01-19T07:00:00ZUA
Event: Open Invitation for Tours – For Lease: 850 N 5th Street Innovation Center by Wexford Science+TechnologyEvent: Open Invitation for Tours – For Lease: 850 N 5th Street Innovation Center by Wexford Science+Technology<div class="ExternalClass5423C1D4E40A4266B8AFB3D3245DE05F"><html>​​<span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">After years of visioning, planning, and construction, 850 N 5th Street is available for lease.​</span><span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;" id="ms-rterangepaste-end"></span><span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">. The building is a collaborative effort between the City of Phoenix, Arizona State University, and Wexford Science & Technology, LLC. Totaling 227,000 SF with 100,000 SF of commercial lab or office space on the top three floors above Arizona State University research and innovation and GateWay Community College's Center for Entrepreneurial Innovation. 850 N 5th Street will be a gathering hub for life science and biomedical innovation. The building is part of ongoing expansion on the Phoenix Biomedical Campus, connecting the downtown biomedical campus to the Roosevelt Row Arts District. Designed to integrate research, entrepreneurial activity, and corporate engagement, 850 N 5th Street serves as a bridge between the surrounding neighborhoods, the academic community, and the professional community. The building's design purposefully invites the neighborhood to participate in its success through the first-floor program elements that are visually porous and accessible. A portion of the building will include turn-key lab space for private research, growing companies, or a soft-landing option for larger companies locating in Phoenix.</span><br><p> </p><p>To schedule a tour or receive information about available lease space please contact Kyle Jardine at <a target="_blank" href="mailto:%20Kyle.Jardine@wexfordscitech.com"><strong>Kyle.Jardine@wexfordscitech.com​</strong></a>  480.779.7181<br></p><p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/108/HKs wexford 2018 v1-NE.jpg2021-01-19T07:00:00ZWexford
EXACT SCIENCES LICENSES TARGETED DIGITAL SEQUENCING METHOD TO EXTEND LEADERSHIP IN PRECISION ONCOLOGYEXACT SCIENCES LICENSES TARGETED DIGITAL SEQUENCING METHOD TO EXTEND LEADERSHIP IN PRECISION ONCOLOGY<div class="ExternalClassBC85741865824F7DA0A12B1185AD30A1"><html> <p>​<span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;box-sizing:border-box;border-radius:0px;">Written by</span><span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;"> </span><span class="uBlogsy_author_name" style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;box-sizing:border-box;border-radius:0px;"><a target="_blank" href="https://www.tgen.org/news/?author=Steve+Yozwiak" title="Steve Yozwiak" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;">Steve Yozwiak</a></span></p> <div class="row" style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"> <div class="col-md-12" style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;"> <ul class="list-inline posted-info" style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;"> <em style="background-color:window;box-sizing:border-box;border-radius:0px;">​Worldwide Exclusive License Provides Access to Targeted Digital Sequencing (TARDIS) Blood Biopsy Method for Use in Minimal Residual Disease Testing</em></ul> <br> </div> </div> <div class="row" style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"> <div class="col-md-12" style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">MADISON, Wis. — January 13, 2021 —</span> <a target="_blank" href="https://www.exactsciences.com/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Exact Sciences Corp.</a> (Nasdaq: EXAS) today announced that it has acquired a worldwide exclusive license to the proprietary TARDIS technology from the <a target="_blank" href="https://www.tgen.org/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a target="_blank" href="https://www.cityofhope.org/homepage" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">City of Hope</a>. This compelling and technically distinct approach will help expand Exact Sciences’ leadership in precision oncology and offers a differentiated patient-specific solution in minimal residual disease testing.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Analysis of DNA shed into a patient’s blood stream can provide a noninvasive means of detecting the presence of a tumor. Patients who have undergone initial treatment may only have small amounts of tumor DNA in their blood, which can be difficult to detect with conventional technology. TARDIS was developed to be highly sensitive and customizable for each patient, including those with only a trace amount of tumor remaining following surgery or other localized treatment that is undetectable by imaging.<span style="box-sizing:border-box;border-radius:0px;font-size:10.5px;line-height:0;vertical-align:baseline;top:-0.5em;">i</span> </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Exact Sciences is uniquely positioned to lead cancer diagnostics with our broad foundation and the talented team that created Cologuard® and Oncotype DX®,” said Kevin Conroy, chairman and CEO of Exact Sciences. “We’re excited to work with TGen and City of hope to bring the incredible TARDIS technology to physicians and patients and deliver a better solution in minimal residual disease to improve cancer patient outcomes.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">In a study published in <a target="_blank" href="https://stm.sciencemag.org/content/11/504/eaax7392" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;"><em style="box-sizing:border-box;border-radius:0px;">Science Translational Medicine</em></a>, TARDIS demonstrated high accuracy in assessing molecular response and residual disease during neoadjuvant therapy to treat breast cancer. TARDIS achieved up to 100-fold improvement beyond the current limit of circulating tumor DNA detection.<span style="box-sizing:border-box;border-radius:0px;font-size:10.5px;line-height:0;vertical-align:baseline;top:-0.5em;">i</span></p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Blood-based diagnostics are critical to the future of cancer care, and licensing TARDIS to an industry leader like Exact Sciences speaks volumes about its potential to positively impact the field,” said Jeffrey M. Trent, Ph.D., TGen president and research director. “The scale and reach Exact Sciences brings to the market means greater access — and new hope — for patients faced with a cancer diagnosis.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">TGen became a part of City of Hope in 2016 to accelerate the speed at which scientists and medical staff convert research discoveries into cures for patients. City of Hope is a National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, making it a national leader in advancing research and treatment protocols.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“We are proud of the innovation driven by TGen in the development of TARDIS technology and are excited about the licensing agreement with Exact Sciences as its leadership in screening and diagnostics combined with this novel approach will address a very important clinical challenge in cancer care,” said Robert Stone, president and CEO, City of Hope. “This is another example of City of Hope working with a leading organization around a joint vision to develop truly world-class solutions to transform the treatment of cancer patients.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">XMS Capital is serving as financial advisor to Exact Sciences, and K&L Gates is serving as legal advisor. Citi is serving as financial advisor to TGen and City of Hope, and Jones Day is serving as legal advisor.<br style="box-sizing:border-box;border-radius:0px;"><br style="box-sizing:border-box;border-radius:0px;"></p> </div> </div> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/133/Dr. Jeffrey Trent.jpg2021-01-13T07:00:00ZTGen
Opportunity: Helios Scholars at TGen – deadline to apply February 5, 2021Opportunity: Helios Scholars at TGen – deadline to apply February 5, 2021<div class="ExternalClass6227C5F5B43441979FFC777FB0F4E917"><html> <p>​<span id="ms-rterangepaste-start"></span>Do you want to experience what it's really like to be a scientist? Helios Scholars at TGen is a paid, eight-week summer internship program in biomedical research open to incoming and continuing undergraduate, graduate, and medical school students who have studied at an Arizona high school, college, or university. Interns work full-time on a research project under the mentorship of a TGen scientist to unravel the genetic components of diabetes, neurological disease and cancer. At TGen North in Flagstaff, interns focus their summer research on public health and pathogens such as Valley Fever and antibiotic resistant bacteria.<br> <br>Internships are available in all areas of translational bioscience: laboratory research, computational biology and bioinformatics, mathematics and statistics, and research administration.​<span id="ms-rterangepaste-end"></span><br></p><p><br></p><p><span style="font-size:11.0pt;font-family:"calibri",sans-serif;"><a href="https://www.tgen.org/education/helios-scholars-at-tgen/" target="_blank">Helios Scholars at TGen – deadline to apply February 5, 2021</a></span>​ (Click Here)<br></p> </html></div>2021-01-12T07:00:00ZTGen
Event: Annual reimagine Health Research Symposium – January 21Event: Annual reimagine Health Research Symposium – January 21<div class="ExternalClass38D5C8369F5A4DA5AFD1BA474E0D2ECE"><html> <p><a href="https://phoenixmed.arizona.edu/reimaginehealth" target="_blank">Click Here For More​</a><br></p> <p>The symposium will focus on current topics in the areas of <em>Intervention and Prevention</em> of important diseases that are impacting humankind. It will emphasize approaches for a variety of diseases and crises — including COVID-19, cardiovascular disease, cancer, opioid addiction and the challenge of needing to develop novel antibiotics. Attendees will learn from and engage with leading experts who will present and discuss contemporary treatment and prevention strategies in the areas of drug discovery, vaccine development, addiction management, the use of artificial intelligence, as well as ethical and social factors contributing to these approaches. </p> <p>The 3<sup>rd</sup> Annual reimagine Health Research Symposium will be held on Thursday, January 21, 2021. Attendees will be able to attend the symposium virtually via Zoom.​<br></p> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/130/reimagine health symposium.jpg2021-01-12T07:00:00ZUA
Event: AZBIOPEERS Meeting R&D Tax Credits - January 19Event: AZBIOPEERS Meeting R&D Tax Credits - January 19<div class="ExternalClass797B8FFE940548B5996BCD599B31F32B"><html> <a target="_blank" href="https://www.azbio.org/events/azbiopeers-january-meeting-rd-tax-credits">Click here for more info:​</a><br><br> <p>The Research and Development (R&D) Tax Credit remains one of the best opportunities for biotech and medtech businesses to substantially reduce their tax liability. Learn how what you and your team are doing today can qualify for federal and state tax savings that can be used to grow your business and move your innovation time line forward faster. Learn more about both the Federal and Arizona R&D Tax Credit opportunities in this 1 hour session. Register to attend on January 19, 2021 from 8-9am.​<br></p> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/131/AZBio-PEERS-Cropped.jpg2021-01-12T07:00:00ZPhoenix Bio News
​Fauci Effect' Boosts Medical School Applications, Motivates Students​Fauci Effect' Boosts Medical School Applications, Motivates Students<div class="ExternalClassB1A71EE0CA9B4FA3AFBE586DDFC581CA"><html> <h1 style="box-sizing:border-box;font-size:20px;margin:0px 0px 0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:25px;color:rgb(30, 82, 136);" class="node--title"><span style="box-sizing:border-box;" class="field field--name-title field--type-string field--label-hidden">KTAR News</span></h1><p>​Glen Fogerty, PhD, associate dean of Admissions and Recruitment, and Meher Rakkar, Class of 2024, joined <em>KTAR News 92.3 FM </em>to discuss the "Fauci Effect" and how it has effected medical school applicants, as well as the admissions cycle.​<br></p><p><span style="font-size:13.3333px;">​Click here to read story: </span><a style="font-family:inherit;font-size:10pt;background-color:window;" href="https://phoenixmed.arizona.edu/newsroom/news/ktar-news" target="_blank">Fauci Effect' Boosts Medical School Applications, Motivates Students</a><br><br></p> <p> <br> </p> </html></div>2021-01-07T07:00:00ZUA
PBC TODAYPBC TODAY<div class="ExternalClass053903287AB64179990494A2463A2190"><html> <p>​<span style="color:rgb(83, 102, 127);font-family:verdana, geneva, sans-serif;font-size:11px;font-style:italic;font-weight:bold;background-color:window;">An Update on the People, Places, and Possibilities of the Phoenix Biomedical Campus in Downtown Phoenix • Oversight provided by Arizona State University President Michael Crow, Northern Arizona University President Rita Cheng, University of Arizona President Robert Robbins, Arizona Board of Regents Executive Director John Arnold and City of Phoenix Mayor Kate Gallego</span></p> <div align="left"> <a href="https://myemail.constantcontact.com/The-latest-news-about-the-Phoenix-Biomedical-Campus.html?soid=1102821891921&aid=O5-JEzN1F4U" target="_blank">Click Here for Web Version​</a><br> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;font-family:verdana, geneva, sans-serif;">PBC now home to Phoenix VA Health Care System Research Space</span> </div> <div align="left"> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">The Phoenix VA Health Care System (PVAHCS) Research Space opened last month in the University of Arizona College of Medicine-Phoenix on the </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="https://phoenixmed.arizona.edu/campus">Phoenix Biomedical Campus</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">. This innovative partnership will accelerate the application of medical research discovery into clinical practice. The newest partnership will allow UArizona researchers access to a secure database of medical and genetic information gathered by the VA (the Million Veterans Program, also known as “MVP”) to provide personalized treatments for veterans. The genetic information will help physicians predict how patients will respond to medications and other treatments. It also will identify patients who may be eligible for a specific research study and invite them to participate in the investigation. The MVP program will provide science collaborators access to the richest medical genetic database in the world. These collaborations will help facilitate early disease intervention, prevent adverse reactions to drugs, save lives, decrease health care costs, and improve the quality of life for veterans.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">“Our veterans have earned and deserved the best possible health care, and we believe that the best possible health care can only happen through innovation,” said Samuel Aguayo, MD, associate chief of staff for research at the </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="https://phoenixmed.arizona.edu/phoenix-va">Phoenix VA Health Care System</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">. “Our veterans are volunteering for our research studies because they understand that the benefit is for them and for others.” Dr. Aguayo, a distinguished pulmonologist, is the inaugural director of this PVAHCS Research Space. “We are blessed with a number of people who have a common vision,” he said. A special thank you to UArizona College of Medicine Dean Guy Reed MD for facilitating this important addition to the PBC. For more information, </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="https://uahs.arizona.edu/news/uarizona-college-medicine-phoenix-and-phoenix-va-launch-innovative-research-space">click here</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;font-family:verdana, geneva, sans-serif;">Connect2STEM 2021 goes virtual Jan. 30</span> </div> <div align="left"> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">The University of Arizona College of Medicine-Phoenix, along with partners, Cox Communications, and the Arizona SciTech Institute, present Connect2STEM 2021 – a series of live virtual events starting January 30 at 10 a.m. showcasing the wonders of science, technology, engineering, math, and medicine (STEM). Connect2STEM is the signature kickoff event for Arizona’s 10th annual </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="https://scitechinstitute.org/scitech-festival/">SciTech Festival</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">, a two-month campaign in February and March that promotes STEM events across the state. The wildly popular event has been reimagined as an </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="https://phoenixmed.arizona.edu/about/videos/connect2stem-returns-january-30-2021">online interactive pavilion</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">. Activities led by physicians, performers, and STEM professionals will debut on Jan. 30. The dynamic kickoff event features a special visit to the Wildcat Play Hospital, an opportunity to scrub in with a world-renowned neurosurgeon, treating pediatric simulation patient, “Hal,” who helps train future doctors, learning how to TikTok your way to a STEM career with Cox Communications and cheering on energetic performances from the Be Kind Crew and Arizona School for the Arts.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">Attendees are encouraged to register for the virtual event at </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="http://phoenixmed.arizona.edu/c2s">phoenixmed.arizona.edu/C2S</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;"> and those who register will automatically be entered to win an iPad. “The future will present new challenges that require inquisitive minds to solve,” said Guy Reed, MD, MS, dean of the UArizona College of Medicine-Phoenix. “Through Connect2STEM, we hope to inspire the next generation of creative thinkers, skilled innovators and compassionate leaders to pursue careers in STEM.” Connect2STEM has welcomed more than 40,000 attendees over the last six years to downtown Phoenix. “Arizona’s future depends on a highly-trained workforce – particularly in the areas of advanced medical technology, research, and related STEM fields – and the SciTech Festival delivers on that vision,” said Phoenix Mayor </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="https://azbigmedia.com/business/business-leaders/newsmakers/get-to-know-phoenix-mayor-kate-gallego/">Kate Gallego</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">. “I am particularly grateful to the University of Arizona and Phoenix Biomedical Campus for organizing this year’s event and for engaging young minds during this challenging time.”</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;font-family:verdana, geneva, sans-serif;">Connect2STEM LIVE TV launched</span> </div> <div align="left"> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;">Connect2STEM LIVE TV is a brand-new series launching Feb. 6 and continues with free online programming every Saturday in February. Featuring faculty, staff, and students from all five University of Arizona Health Sciences colleges including Nursing, Pharmacy, Public Health, and both medical schools in Phoenix and Tucson, dynamic STEM modules will allow youth of all ages to discover STEM careers and activities. Regents’ Professor Allan Hamilton, MD, FACS, a world-renowned neurosurgeon and executive director of the Arizona Simulation Technology Education Center will host an introduction to medicine over multiple sessions. Dr. Hamilton currently holds four professorships at the University of Arizona in Neurosurgery, Radiation Oncology, Psychology, and Electrical and Computer Engineering. Dr. Hamilton has also served as Senior Medical Script Consultant on Grey’s Anatomy for more than 15 years. </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);font-family:verdana, geneva, sans-serif;" target="_blank" rel="noopener noreferrer" href="https://phoenixmed.arizona.edu/c2s">Click here</a> <span style="font-size:11px;font-family:verdana, geneva, sans-serif;"> to access the full schedule of live programs, printable fun sheets and access to new videos. </span> </div> <div align="left"> <br style="color:rgb(46, 47, 47);font-family:verdana, geneva, sans-serif;font-size:14px;"> <br> </div> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/132/2020.09.15 BSPB 5th-6th Floors-4138 _2_.jpg2021-01-07T07:00:00ZPhoenix Bio News
​Event: CONNECT2STEM 2021 Returns as Dynamic Virtual Experience on Saturday January 30​​Event: CONNECT2STEM 2021 Returns as Dynamic Virtual Experience on Saturday January 30​<div class="ExternalClassCEA26E4021454F9380450CBD751FC062"><html> <p>The University of Arizona College of Medicine – Phoenix, along with partners, <a href="https://www.cox.com/residential/home.html" target="_blank">Cox Communications</a> and the Arizona SciTech Institute, present <strong>Connect2STEM 2021</strong> — a series of <strong>live virtual events</strong> starting January 30<sup>th</sup> at 10:00 AM MST showcasing the wonders of Science, Technology, Engineering, Math and Medicine (STEM). Connect2STEM is the signature kickoff event for Arizona's 10<sup>th</sup> annual statewide <a href="https://scitechinstitute.org/scitech-festival/" target="_blank">SciTech Festival</a>, a two-month campaign in February and March that promotes STEM events across the state. Attendees are encouraged to register for the virtual event at <a href="http://phoenixmed.arizona.edu/c2s" target="_blank">phoenixmed.arizona.edu/C2S</a> and those who register will automatically be entered to win an iPad. </p> <p>“The future will present new challenges that require inquisitive minds to solve," said Guy Reed, MD, MS, Dean of the UArizona College of Medicine – Phoenix. “Through Connect2STEM, we hope to inspire the next generation of creative thinkers, skilled innovators and compassionate leaders to pursue careers in STEM." </p> <p>“Arizona's future depends on a highly-trained workforce – particularly in the areas of advanced medical technology, research, and related STEM fields – and the SciTech Festival delivers on that vision," said Phoenix Mayor Kate Gallego. “I am particularly grateful to the University of Arizona and Phoenix Biomedical campus for organizing this year's event and for engaging young minds during this challenging time."</p> <p> </p> <p>Visit <a href="http://phoenixmed.arizona.edu/c2s" target="_blank"><strong>phoenixmed.arizona.edu/C2S</strong></a> to access the full schedule of live programs, printable fun sheets and access to new videos. ​<br></p> <span id="ms-rterangepaste-end"></span> <p> <br> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/126/c2s2021-promo.jpg2021-01-01T07:00:00ZPhoenix Bio News
2020 Year in Review2020 Year in Review<div class="ExternalClass6D70EC31992A423A87696AE263B17514"><html> <h5 style="box-sizing:border-box;margin-top:0px;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";line-height:18px;color:rgb(155, 155, 155);font-size:15px;margin-bottom:0px !important;margin-right:0.5rem !important;text-transform:uppercase !important;" class="field_title text-uppercase mb-0 mr-2"><span style="box-sizing:border-box;" class="field field--name-title field--type-string field--label-hidden">RYAN LOEBE</span></h5><br><p><a target="_blank" href="https://phoenixmed.arizona.edu/2020year-review" style="background-color:window;font-family:inherit;font-size:10pt;">University of Arizona College of Medicine – Phoenix 2020 Year in Review</a></p> <p>While the world stood still during the majority of 2020 due to the coronavirus pandemic, the University of Arizona College of Medicine – Phoenix community remained focused in educating the next generation of physicians, advancing innovative medical research and advocating for underrepresented individuals in health care. In case you missed our top stories this past year, here's an overview of what our students, staff and faculty have accomplished in 2020.​<br></p> <p> <br> </p> </html></div>2020-12-18T07:00:00ZUA
TGEN IDENTIFIES GENE THAT COULD EXPLAIN DISPARITY IN COVID-19 EFFECTSTGEN IDENTIFIES GENE THAT COULD EXPLAIN DISPARITY IN COVID-19 EFFECTS<div class="ExternalClassF93A9EFA46CD4466A7B8F5682AD30D2A"><html> <ul style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="list-inline posted-info"><li style="box-sizing:border-box;border-radius:0px;display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;"><div style="box-sizing:border-box;border-radius:0px;"><span style="box-sizing:border-box;border-radius:0px;">Written by</span> <span style="box-sizing:border-box;border-radius:0px;" class="uBlogsy_author_name"><a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;" title="Steve Yozwiak" href="https://www.tgen.org/news/?author=Steve+Yozwiak" target="_blank">Steve Yozwiak</a></span></div></li><li style="box-sizing:border-box;border-radius:0px;display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;"><div><br><br></div></li></ul> <span id="ms-rterangepaste-end"></span> <p> </p><span id="ms-rterangepaste-start"></span><div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"><div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"><em style="box-sizing:border-box;border-radius:0px;">Comparative analysis of human and animal coronaviruses strains implicates miR1307</em></p></div></div><div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"><div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"><span style="box-sizing:border-box;border-radius:0px;font-weight:700;">PHOENIX, Ariz. — Dec. 15, 2020 —</span> The <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/" target="_blank">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.cityofhope.org/homepage" target="_blank">City of Hope</a>, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">The study results, recently published in the journal <em style="box-sizing:border-box;border-radius:0px;">mSphere,</em> describe a molecule made from DNA — miR1307 — as a potential dimmer switch that may influence the severity of the disease; why some infected with SARS-CoV-2, the virus that causes COVID-19, have mild or even no symptoms, while others become seriously ill or die.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Led by <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/faculty-profiles/nik-schork/" target="_blank">Nicholas Schork, Ph.D.</a>, a Distinguished Professor and Director of TGen’s Quantitative Medicine and Systems Biology Division, researchers identified miR1307 by comparing the genetic elements of SARS-Cov-2 with seven other human coronaviruses, some of which merely cause common colds. In addition, they examined the genomes of coronavirus strains known to infect bats, pigs, pangolins, ferrets, civets and chickens.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“We pursued a systematic gene-by-gene comparative analysis, investigating how and to what extent the SARS-CoV-2 genome sequence differs from other well-characterized human and animal coronavirus genomes,” Dr. Schork said. “Our study results will allow the development of models of how the virus and its hosts interact, enhancing our understanding of the disease-causing mechanisms of SARS-CoV-2 and how to exploit both viral and host therapeutic targets.”</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Study results suggest that miR1307 serves as a switch that turns various genes within the virus on or off, potentially making the disease more or less harmful to patients by regulating, for example, how fast or slow the virus replicates. In past studies, miR1307 has been found to affect the severity of several types of cancer, lung disease and the flu, specifically the H1N1 influenza virus that caused a 2009 pandemic. It was first discovered as a key regulatory agent in the Epstein-Barr virus, best known as the cause of infectious mononucleosis.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">According to Dr. Schork, the study results also provide the basis for additional investigations, such as designing vaccines based on proteins or RNA, developing specific genetic markers for community disease monitoring, and tracing COVID-19 from one species to another.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Funding for this study was provided by National Science Foundation (RAPID grant # 2031819). Computing infrastructure was provided by Dell Technologies.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">The study — <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://msphere.asm.org/content/5/6/e00754-20" target="_blank"><em style="box-sizing:border-box;border-radius:0px;">Conserved Genomic Terminals of SARS-CoV-2 as Coevolving Functional Elements and Potential Therapeutic Targets</em></a> — was published Nov. 27 in <em style="box-sizing:border-box;border-radius:0px;">mSphere</em>.​<br></p></div></div><span id="ms-rterangepaste-end"></span><p><br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/120/TGenFaculty.jpg2020-12-15T07:00:00ZTGen
COMPOUND DERIVED FROM THUNDER GOD VINE COULD HELP PANCREATIC CANCER PATIENTSCOMPOUND DERIVED FROM THUNDER GOD VINE COULD HELP PANCREATIC CANCER PATIENTS<div class="ExternalClass22E43BDF45614BE68AF9DB760909C2A9"><html> <p>​<span id="ms-rterangepaste-start"></span><span style="box-sizing:border-box;border-radius:0px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;font-style:italic;">Written by</span><span style="color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;font-style:italic;"> </span><span class="uBlogsy_author_name" style="box-sizing:border-box;border-radius:0px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;font-style:italic;"><a target="_blank" href="https://www.tgen.org/news/?author=Steve+Yozwiak" title="Steve Yozwiak" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;"><span style="box-sizing:border-box;border-radius:0px;">Steve Yozwiak</span></a></span>​<span id="ms-rterangepaste-end"></span><br></p><span id="ms-rterangepaste-start"></span><div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;" class="row"><div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"><em style="box-sizing:border-box;border-radius:0px;">TGen-led study indicates drug attacks ‘super-enhancers’ in the DNA of cancer cells and in the stromal cocoon that hides the tumor from the immune system</em></p></div></div><div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;" class="row"><div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"><span style="box-sizing:border-box;border-radius:0px;font-weight:700;">PHOENIX, Ariz. — Dec. 14, 2020 —</span> The results of a pre-clinical study led by researchers at the <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/" target="_blank">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.cityofhope.org/homepage" target="_blank">City of Hope</a>, suggest how a compound derived from the thunder god vine — an herb used in China for centuries to treat joint pain, swelling and fever — is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">The medicinal plant’s key ingredient, triptolide, is the basis of a water-soluble prodrug called Minnelide, which appears to attack pancreatic cancer cells and the cocoon of stroma surrounding the tumor that shields it from the body’s immune system. Investigators recently published the study results in the journal <em style="box-sizing:border-box;border-radius:0px;">Oncogenesis</em>.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">The study found that the compound’s mechanism of action is the ability of triptolide (Minnelide) to disrupt what are known as super-enhancers, strings of DNA needed to maintain the genetic stability of pancreatic cancer cells and the cancer-associated-fibroblasts that help make up the stroma surrounding the cancer.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">“The cancer cells rely on super-enhancers for their growth and survival,” said <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/faculty-profiles/haiyong-han/" target="_blank">Dr. Haiyong Han</a>, a Professor in TGen’s Molecular Medicine Division and one of the study’s senior authors. “We found that by disrupting these super-enhancers triptolide not only attacks the cancer cells, but also the stroma, which helps accelerate cancer cell death.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">“While triptolide has been known to be a general transcriptional inhibitor and a potent antitumor agent, we are the first to report its role in modulating super-enhancers to regulate the expression of genes, especially cancer-causing genes,” said Dr. Han, who also is head of the basic research unit in TGen’s Pancreatic Cancer Program.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">Pancreatic cancer is the third leading cause of cancer-related death in the U.S., annually killing more than 47,000 Americans.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">“There is an urgent need to identify and develop treatment strategies that not only target the tumor cells, but can also modulate the stromal cells,” said <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/faculty-profiles/daniel-von-hoff/" target="_blank">Dr. Daniel Von Hoff</a>, TGen Distinguished Professor and another senior author of the study.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">“Based on our findings, using modulating compounds such as triptolide to reprogram super-enhancers may provide means for effective treatment options for pancreas cancer patients,” said Dr. Von Hoff, considered one of the nation’s leading authorities on pancreatic cancer.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">Thunder god vine (<em style="box-sizing:border-box;border-radius:0px;">Tripterygium wilfordii</em>), also known as léi gōng téng, is native to China, Japan and Korea. Traditional Chinese medicine has used the vine for more than 2,000 years as a treatment for everything from fever to inflammation and autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. The chemical compound triptolide is among the more than 100 bioactive ingredients derived from the thunder god vine.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">The study — <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.nature.com/articles/s41389-020-00285-9" target="_blank"><em style="box-sizing:border-box;border-radius:0px;">Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts</em></a> — was published Nov. 9 in <em style="box-sizing:border-box;border-radius:0px;">Oncogenisis</em>.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">Also contributing to this study were: Baylor Scott & White Research Institute, Salk Institute for Biological Studies and the Howard Hughes Medical Institute.</p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;">Funding for this study was provided by grants from: Stand Up To Cancer (SU2C)-Lustgarten Foundation Pancreatic Cancer Dream Team; Baylor Scott & White Research Institute; the National Foundation for Cancer Research. Additional support was provided by: the Damon Runyon Cancer Research Foundation; the National Institutes of Health; the Salk Cancer Center; and the Samuel Waxman Cancer Research Foundation. </p><div><br>​<br></div></div></div><span id="ms-rterangepaste-end"></span><p><br></p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/121/dr_haiyong_han.jpg2020-12-14T07:00:00ZTGen
Medical School and Phoenix VA Launch Innovative Research SpaceMedical School and Phoenix VA Launch Innovative Research Space<div class="ExternalClass5CF2DF641A5340868C15597EF596AD52"><html> <p>​</p> <span id="ms-rterangepaste-start"></span> <div style="box-sizing:border-box;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;font-size:1.25rem;color:rgb(33, 33, 33) !important;" class="field field--name-field-subtitle field--type-string field--label-hidden h5 mb-lg-3 text-dark field__item">The Phoenix VA Health Care System (PVAHCS) Research Space will be an Incubator for Medical Discovery, New Technologies and Clinical Care on the Phoenix Biomedical Campus</div> <div style="box-sizing:border-box;color:rgb(96, 96, 96);font-size:15px;line-height:20px;margin-bottom:3rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The Phoenix VA Health Care System (PVAHCS) Research Space will open this month in the University of Arizona College of Medicine – Phoenix on the <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/campus" target="_blank">Phoenix Biomedical Campus</a>. This innovative partnership will accelerate the application of medical research discovery into clinical practice.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p> <figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:250px;height:auto;background-color:rgb(232, 237, 243) !important;"> <div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"> <img style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" title="Samuel Aguayo, MD" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/va-partnership-aguayo.jpg" data-entity-uuid="6d7cf847-c813-4bb2-bf1e-804cd9be7ee6" data-entity-type="file" class="img-fluid" alt="Samuel Aguayo, MD" /> </div> <figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"> <em style="box-sizing:border-box;">Samuel Aguayo, MD</em> </figcaption> </figure>The newest partnership will allow UArizona researchers access to a secure database of medical and genetic information gathered by the VA (the Million Veterans Program, also known as “MVP”) to provide personalized treatments for veterans. The genetic information will help physicians predict how patients will respond to medications and other treatments. It also will identify patients who may be eligible for a specific research study and invite them to participate in the investigation. The MVP program will provide science collaborators access to the richest medical genetic database in the world. These collaborations will help facilitate early disease intervention, prevent adverse reactions to drugs, save lives, decrease health care costs and improve quality of life for veterans.<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“Our veterans have earned and deserve the best possible health care, and we believe that the best possible health care can only happen through innovation,” said Samuel Aguayo, MD, associate chief of staff for research at the <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/phoenix-va" target="_blank">Phoenix VA Health Care System</a>. “Our veterans are volunteering for our research studies because they understand that the benefit is for them and for others.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Dr. Aguayo, a distinguished pulmonologist, is the inaugural director of this PVAHCS Research Space. “We are blessed with a number of people who have a common vision,” he said.</p><div style="box-sizing:border-box;width:696px;padding:0px;overflow:hidden;" class="embed-responsive embed-responsive-16by9"></div><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Phoenix continues<span style="box-sizing:border-box;font-weight:bolder;"> </span>to grow<span style="box-sizing:border-box;font-weight:bolder;"> </span>with more than 6,000 people moving to the area monthly. This trend is expected to increase as employment opportunities and cost of living make Phoenix a highly desirable metropolitan community. The fifth largest city in the United States, Phoenix needs skilled physicians and health care professionals to care for its growing population.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><figure class="bg-light figure img-fluid align-left" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 1rem 1rem 0px;float:left;max-width:250px;height:auto;background-color:rgb(232, 237, 243) !important;"><div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"><img style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" title="Dean Guy Reed, MD, MS" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/va-partnership-reed.jpg" data-entity-uuid="fd278340-79b0-4b9e-aab5-60ecf32c9922" data-entity-type="file" class="img-fluid" alt="Dean Guy Reed, MD, MS" /></div><figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"><em style="box-sizing:border-box;">Dean Guy Reed, MD, MS</em></figcaption></figure>The PVAHCS provides health care for more veterans every year, as the growth in enrollments continually climbs. This synergistic collaboration will help serve the community by recruiting renowned clinical talent to practice medicine at the PVAHCS and conduct research at the UArizona College of Medicine – Phoenix. They will also develop the next generation of skilled clinical researchers through a variety of <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/gme" target="_blank">residency and fellowship programs</a>.<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">A culmination of tireless efforts among the college, the PVAHCS, the City of Phoenix Economic Development office and the Mayor of Phoenix’s office, the state-of-the-art research space showcases the dedication to driving economic development and providing life-changing medical treatments for veterans and the Phoenix community. For Dr. Aguayo, this research space is a vision he and others have worked for the last decade to create.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“The Phoenix VA and University of Arizona College of Medicine – Phoenix continue to lead by developing first-in-the-nation partnerships that serve as a role model for other academic medical centers across the country,” explained City of Phoenix Mayor Kate Gallego. “We are proud to support the Phoenix Biomedical Campus for continuing to be a key generator of economic impact for Phoenix and Arizona.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Since opening in 2007, the UArizona College of Medicine – Phoenix has partnered with the PVAHCS to prepare the college’s medical students and residents on the diverse health needs of veterans. As part of that collaboration, many third-year medical students rotate through the PVAHCS during their clerkships, in which they learn first-hand from top doctors how to provide excellent care to veterans.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:250px;height:auto;background-color:rgb(232, 237, 243) !important;"><div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"><img style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" title="The Phoenix VA Health Care System" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/phoenix-va-story.jpg" data-entity-uuid="fe017c33-b654-489f-82e6-bfdb16cd6290" data-entity-type="file" class="img-fluid" alt="The Phoenix VA Health Care System" /></div><figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"><em style="box-sizing:border-box;">The Phoenix VA Health Care System</em></figcaption></figure>The college has more than 155 faculty members with affiliation at the Phoenix VA who serve as department chairs, committee chairs, mentors and advisors. These faculty members also participate in the doctoring program, clerkships, core lecture series and <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/scholarly-project" target="_blank">scholarly projects</a>.<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The partnership has grown through the years spanning many departments, including <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/radiology" target="_blank">radiology</a>, <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/neurology" target="_blank">neurology</a>, dermatology, <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/medicine" target="_blank">internal medicine</a> and, most recently, <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/bmi" target="_blank">clinical informatics</a>.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“We have worked hard to expand our collaboration with the Phoenix VA, and to enhance the scope of research on the campus,” said <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/dean-reed" target="_blank">Guy Reed, MD, MS</a>, dean of the UArizona College of Medicine – Phoenix. “Our investigators will help use this data to treat illnesses in areas of unmet medical need, such as mental health, traumatic brain injury, skin cancer, heart disease and numerous other conditions. The insights that they gain will fuel the development of new therapies, new algorithms, new devices, new approaches for improving care.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">A direct benefit to patients will be the ability to attract top talent in a variety of specialties, individuals who participate in research and education in addition to treating patients. The Phoenix community will benefit from having a thriving health sciences campus.​<br></p></div> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>2020-12-10T07:00:00ZUA
PBC TODAYPBC TODAY<div class="ExternalClass5FFE681789F545999F7B4BBA595C82DE"><html> <p>​</p> <span id="ms-rterangepaste-start"></span><table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;font-style:italic;">An Update on the People, Places, and Possibilities of the Phoenix Biomedical Campus in Downtown Phoenix • Oversight provided by Arizona State University President Michael Crow, Northern Arizona University President Rita Cheng, University of Arizona President Robert Robbins, Arizona Board of Regents Executive Director John Arnold and City of Phoenix Mayor Kate Gallego</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">December 10, 2020</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">Diagramming PBC’s Unique Positioning</span> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">The Phoenix Biomedical Campus (PBC) is the hub of an ever-growing central Phoenix bioscience eco-system that includes seven biomedical and health-related colleges among our three public universities and five hospital systems. The PBC is also connected with the robust, urban amenity package in Downtown Phoenix. With the help of ABOR graphic designer Kendra Pelofske, we have created a Venn diagram and other facts and figures to depict the interconnected nature of PBC entities. </span> <a href="https://azregents.edu/sites/default/files/public/pbc/PBC_VennDiagram.pdf" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">Take a peek.</a> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">New Name, New Hires at Dignity Health Care Center</span> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">Dignity Health Cancer Institute is the new name of the former University of Arizona Cancer Center at Dignity Health St. Joseph’s Hospital and Medical Center, reflecting a renegotiated facility lease agreement that permits Dignity to lease the entire cancer center facility from the University of Arizona for continued operation of an outpatient cancer center as well as other related clinical activities. Several new physicians have been hired, including Dr. George Kallingal, urologic oncologist; Dr. Vamsee Torri, medical oncologist for the Gastrointestinal and Genitourinary Multidisciplinary Cancer Program; Dr. Darshan Vairavamurthy, rehabilitation and palliative specialist for the Support Care and Survivorship Program; Dr. Jason Wiseman, surgical oncologist for the Melanoma and Sarcoma Multidisciplinary Program; and Lauren Wallace, genetic counselor. As you can imagine, everything right now is about caring for COVID-19 patients. For more information, </span> <a href="https://urldefense.com/v3/__http:/dignityhealth.org/CancerInstituteAZ__%3b%21%21IKRxdwAv5BmarQ%21KxQCDIU_3ULERjezlVOpjY_8aPph79IfopnLbopirdqvo3veFGFkmVlJNzeeqgpRtBRriRI$" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">visit their website</a> <span style="font-size:11px;color:rgb(0, 0, 0);"> or contact </span> <a href="mailto:Marcia.Gruber-Page@DignityHealth.org" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">Marcia Gruber-Page</a> <span style="font-size:11px;color:rgb(0, 0, 0);">, vice president of oncology services, Dignity Health Cancer Institute.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">Encouraging Connection for Black, African-American, Caribbean Faculty and Staff</span> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">In June 2020, the BAAC (Black/African-American/Caribbean) Faculty and Staff Resource Group was created at the University of Arizona College of Medicine-Phoenix. The group’s mission is to be a collective voice for BAAC staff and faculty in supporting the community at the Phoenix Biomedical Campus and promoting and encouraging advancement, leadership, and networking for BAAC faculty and staff campus-wide. The group meets monthly to encourage connection, service, and community activism. Future initiatives include community outreach, guest speakers, and social events. For more information or to join the group, contact </span> <a href="mailto:npitre@email.arizona.edu?subject=BAAC" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">Nicole Pitre-Ewing</a> <span style="font-size:11px;color:rgb(0, 0, 0);">, manager of assessments & evaluation and pre-clerkships, The University of Arizona College of Medicine-Phoenix.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">Updated PBC Brochure</span> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">Life at the Phoenix Biomedical Campus is not static. As changes happen, the City of Phoenix’s handy brochure summarizes the latest and greatest at PBC. Thanks to Claudia Whitehead for her assistance in creating this brochure. View the most current version </span> <a href="/Documents/Phoenix%20Biomedical%20Campus%202020.pdf" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">here</a> <span style="font-size:11px;color:rgb(0, 0, 0);">.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(235, 169, 66);font-weight:bold;">Mark your calendar…</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">AZBio Trailblazers</span> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">On Thursday, December 10, 2020 at 11 a.m., join AZBio and members of Arizona business and bioscience community for a virtual event to honor Arizona legislators and other state and local elected officials who have made it possible for Arizona’s bioscience industry to gain national recognition, build capital infrastructure, and take its place as a leader in scientific discovery and job growth. For more information and to register, </span> <a href="https://www.azbio.org/events/trailblazers-2020" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">click here</a> <span style="font-size:11px;color:rgb(0, 0, 0);">.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">Taking Back Control During COVID-19: Leading Innovation Through Uncertain Times</span> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">On Wednesday, December 16, 2020 at 9 a.m., ASU President Dr. Michael M. Crow and Dr. Rajiv J. Shah, president of The Rockefeller Foundation, will discuss their strategies for leading organizations during COVID-19. Their lessons on innovation, flexibility, and collaboration can be applied broadly. Learn how these two leaders are using innovative solutions to optimize the health and well-being of the communities they serve. For more information and to register, </span> <a href="https://na.eventscloud.com/ereg/newreg.php?eventid=576950&" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">click here</a> <span style="font-size:11px;color:rgb(0, 0, 0);">.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;">ASU Biomedical Innovation Speaker Series</span> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">From the comfort of your home office, </span> <a href="https://www.youtube.com/playlist?list=PL00PFxcH85LNrpaj4ozTqpOUvJ8SQYGZL" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);">view the four-video series</a> <span style="font-size:11px;color:rgb(0, 0, 0);">, sponsored by the Arizona Biomedical Research Centre, featuring top experts in the bioscience field. Topics cover:</span> </div> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(83, 102, 127);text-align:left;"> <span style="font-weight:bold;">“How Biology will Build the Next Technology Revolution” with Dr. Susan Hockfield</span> </li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(83, 102, 127);text-align:left;"> <span style="font-weight:bold;">“Biomedical Science and Engineering as Critical Levers in the Future of Health Care” with Dr. Vivian Lee</span> </li> </ul> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;"></span> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(83, 102, 127);text-align:left;"> <span style="font-weight:bold;">“Bridging the Gap between Data Science and Medicine” with Drs. Anthony Philippakis and Melissa Haendel</span> </li> </ul> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-weight:bold;"></span> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(83, 102, 127);text-align:left;"> <span style="font-weight:bold;">“Creating Innovation Ecosystems to Drive Knowledge-Led Inclusive Economic Development” with Thomas Osha</span> </li> </ul> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(235, 169, 66);font-weight:bold;">It’s tour time…</span> </div> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.tgen.org/education/tour-tgen/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Sign up for virtual tours of TGen, December 11 or January 14</a>. View the next generation sequencing technology and biomedical research laboratories where TGen scientists unlock the mysteries of cancer, diabetes, rare and neurological diseases.</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;text-align:left;"> <a href="mailto:Kyle.Jardine@wexfordscitech.com?subject=Tour%20of%20850%20N.%205th%20Street" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Sign up for tours of 850 N. 5th Street</a> <span style="color:black;">, the new research and education collaborative effort between the City of Phoenix, Arizona State University, and Wexford Science & Technology, LLC.</span> </li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PEOPLE </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Noteworthy individuals making a difference</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.azbio.org/tgens-and-city-of-hopes-dr-daniel-d-von-hoff-will-receive-inaugural-aacr-scientific-achievement-award" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">TGen’s and City of Hope’s Dr. Daniel D. Von Hoff receive inaugural AACR scientific achievement award</a> (AZBio, 12-06-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:black;text-align:left;">NAU’s Dr. John Heick received the “James A. Gould Excellence in Teaching Orthopaedic Physical Therapy Award” by the Academy of Orthopaedic Physical Therapy of the American Physical Therapy Association (APTA). David Ung, an NAU PT student, was selected as an APTA Centennial Scholar by the Student Assembly Board of Directors. Dr. Amy Armstrong-Heimsoth in the NAU Occupational Therapy Department has earned recognition at NAU's Professional Achievement Award Ceremony, as well as promotion to associate clinical professor due to her exceptional teaching, scholarship, and service.</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PLACES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Properties and new developments where good things happen</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://azbigmedia.com/real-estate/central-phoenix-experiences-boom-in-healthcare-and-bioscience/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">A look inside the Central Phoenix boom in healthcare and bioscience</a> (AZ Big Media, 11-24-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">POSSIBILITIES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Significant research & educational opportunities going on</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="/news-events/116" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">OncoMyx announces assignment of foundational technology and intellectual property portfolio for oncolytic myxoma virus technology</a> (OncoMyx, 12-07, 20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://phoenixmed.arizona.edu/newsroom/news/researchers-awarded-8-million-grant-study-depression-and-cardiovascular-disease" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Researchers awarded $8M grant to study depression and cardiovascular disease</a> (UArizona, 11-30-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://chs.asu.edu/news/how-effective-are-sit-stand-workstations-really" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">How effective are sit-to-stand workstations, really?</a> (ASU College of Health Solutions, 11-24-20)</li> </ul> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);"></span> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://phoenixmed.arizona.edu/newsroom/news/new-training-package-increase-awareness-global-health-issues-ophthalmology" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">New training package to increase awareness of global health issues in ophthalmology</a> (UArizona, 11-02-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PANDEMIC RESPONSE - </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">PBC-affiliated experts weigh in on timely issue</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.bannerhealth.com/healthcareblog/advise-me/5-ways-to-celebrate-safely-with-seniors-this-holiday-season" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">5 ways to celebrate safely with higher-risk loved ones this holiday season</a> (Banner Health, 12-04-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://chs.asu.edu/news/research-shows-pandemic-induced-food-insecurity-rise-arizona" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Research shows pandemic-induced food insecurity on the rise in Arizona</a> (ASU College of Health Solutions, 11-30-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:11px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://asunow.asu.edu/20201119-discoveries-asu-first-comprehensive-survey-how-companies-protect-employees-covid-19" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">ASU releases first comprehensive survey on how companies are protecting their employees from COVID-19</a> (ASU College of Health Solutions, 11-17-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PARTICULARS</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;"> <tbody> <tr> <td class=" editor-col OneColumnMobile" width="100%" align="" valign="top"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text editor-text " align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Contact:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <span style="font-size:12px;color:rgb(0, 0, 0);">David Krietor, Executive Director, 602-741-5580, </span> <a href="mailto:david.krietor@asu.edu" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">david.krietor@asu.edu</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Website:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__biomedicalphoenix.com_&d=DwMFaQ&c=l45AxH-kUV29SRQusp9vYR0n1GycN4_2jInuKy6zbqQ&r=ZkOduS1eiLUbvWLZ-8ug9vL9jHDR32Y_z26zPsk2vak&m=-wKoE3rm1i95DXGiQyqWJla6ia5YA9fsFMAO4vC9trM&s=XmoGrKj6ux3_Hjm5HLDxe1wzR5CGHEalThzpBkYVG90&e=" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">biomedicalphoenix.com</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="mailto:claudia.whitehead@phoenix.gov" rel="noopener noreferrer" target="_blank" style="font-size:12px;color:rgb(0, 0, 0);">Claudia Whitehead</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="mailto:claudia.whitehead@phoenix.gov" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">claudia.whitehead@phoenix.gov</a> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Events Calendar:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a href="https://asuevents.asu.edu/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">ASU</a> <span style="font-size:12px;color:black;">, </span> <a href="https://www.pxu.org/Page/38" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Bioscience H.S.</a> <span style="font-size:12px;color:black;">, </span> <a href="https://events.nau.edu/?view=grid&search=y" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">NAU</a> <span style="font-size:12px;color:black;">, </span> <a href="https://puhsaa.com/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">PUHS Alumni Assoc.</a> <span style="font-size:12px;color:black;">, </span> <a href="https://www.tgen.org/giving/events/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">TGen</a> <span style="font-size:12px;color:black;">, </span> <a href="https://uahs.arizona.edu/events" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">UArizona</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Jobs:</span> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> <a href="https://careers.insidehighered.com/jobs/?Keywords=%22phoenix+biomedical+campus%22#browsing" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Inside Higher Ed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://www.indeed.com/jobs?q=%22phoenix%20Biomedical%20Campus%22&l=Phoenix%2c%20AZ&radius=0&vjk=9d8bff47682c0b93" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Indeed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://jobs.azbio.org/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">AZBio Job Center</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Getting Around:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a href="https://phoenixmed.arizona.edu/campus" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Campus Map</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://www.valleymetro.org/maps-schedules" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Public Transit</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="http://gridbikes.com/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Bike Share</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://parking.arizona.edu/parking/biomedical-campus/index.php?referral=compurchase" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Parking</a>​<br></div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/125/Screen Shot 2020-12-09 at 2.42.27 PM.png2020-12-10T07:00:00ZPhoenix Bio News
Helping kids walk: NAU engineer takes collaborative research into wearable robotics devices to PBCHelping kids walk: NAU engineer takes collaborative research into wearable robotics devices to PBC<div class="ExternalClass25C410F7937647AFB7C6E2B21651A7E8"><html> <p>​<span style="color:rgb(0, 52, 102);font-family:acumin-pro, arial, sans-serif;font-size:16px;background-color:window;">Collaborative research between the three major Arizona universities is helping young people with cerebral palsy (CP) to walk more confidently and safely on their own.</span></p> <div style="box-sizing:border-box;margin-top:2rem;color:rgb(0, 52, 102);font-family:acumin-pro, arial, sans-serif;font-size:16px;" class="entry-content"> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1.75rem;">This research, led by Northern Arizona University mechanical engineering assistant professor <span style="box-sizing:border-box;font-weight:bolder;">Zach Lerner</span>, uses wearable robotic devices to assist a person’s gait and to provide tools that help to retrain their legs how to walk. Lerner, who holds a dual research appointment at the University of Arizona College of Medicine-Phoenix, is working with colleagues from UArizona and Arizona State University at the Phoenix Biomedical Center (PBC).</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1.75rem;">The study, published in the <a style="box-sizing:border-box;color:rgb(0, 87, 171);text-decoration-line:underline;background-color:transparent;transition:all 0.3s ease 0s;" href="https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=9246668" target="_blank">IEEE Open Journal of Engineering in Medicine and Biology</a>, looked at six children with cerebral palsy. Each child came in to the PBC for 10 training sessions with this device; the goal was to measure and retrain each child’s walking gait by strengthening plantar flexors, increasing their speed and reducing the amount of energy needed to walk.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1.75rem;">The wearable device, which added targeted resistance depending on how the child was walking, also provided immediate feedback so the researchers could determine how well the child was doing and what needed to be adjusted, which contributed to better outcomes for every child who participated in the study.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1.75rem;">“Most exoskeleton research has been conducted to provide assistance, aimed at making walking easier. We did the opposite. We used an exoskeleton to provide targeted resistance for neuromuscular gait retraining, aimed at improving long-term function,” Lerner said. “We also used immediate sensorimotor feedback, which we think is really critical for training the participants to use their own muscles more efficiently.”</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1.75rem;">Although the study size was small and lacked a control group, Lerner is pleased with the results of the study, which showed that wearable adaptive resistance training was a feasible and effective tool in improving mobility for individuals with CP, even those with ingrained walking patterns who needed to be retrained. With four weeks of training, every participant improved in every measure of success.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1.75rem;">“We expect that this intervention may be suitable for other patient populations affected by neuromuscular impairment because it aligns with the guiding principles of neuroplasticity—task specificity and top-down active engagement,” the study reads. “This relatively low-cost, battery-powered and wearable intervention was designed for translation to both clinical practice and personal use at home, and as an untethered device, training can take place under a variety of contexts, including overground walking. The inherent accessibility of this wearable intervention provides individuals with the opportunity to significantly increase the frequency of targeted neuromuscular rehabilitation.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1.75rem;">The likely next step for this research is completing additional exoskeleton gait rehabilitation studies at PBC, which is helpful for recruiting larger and more diverse participants.</p> <div style="box-sizing:border-box;" data-url="https://news.nau.edu/lerner-pbc-research/" class="at-below-post addthis_tool"></div> </div> <footer class="entry-footer" style="box-sizing:border-box;margin-top:3rem;color:rgb(33, 37, 41);font-family:acumin-pro, arial, sans-serif;font-size:16px;"> <div style="box-sizing:border-box;font-family:acumin-pro-condensed, arial, sans-serif;font-weight:900;font-size:1.1rem;color:rgb(0, 52, 102);text-transform:uppercase;" class="author">NAU NEWS</div> </footer>​<p><br></p></html></div>https://biomedicalphoenix.com/Lists/News/Attachments/117/NAUkidswalk.png2020-12-10T07:00:00ZNAU
UArizona College of Medicine – Phoenix Inducts Newest Class of Gold Humanism Honor SocietyUArizona College of Medicine – Phoenix Inducts Newest Class of Gold Humanism Honor Society<div class="ExternalClass087E8C49C89B4DF49E601B2B65DAA151"><html> <p>​<span style="color:rgb(155, 155, 155);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;text-transform:uppercase;background-color:window;">TERESA JOSEPH</span></p><p><span style="color:rgb(155, 155, 155);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;text-transform:uppercase;background-color:window;"></span><span style="color:rgb(33, 33, 33);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:1.25rem;font-weight:700;background-color:window;">Students and Faculty Recognized by Peers for Professionalism, Leadership and Humanism</span></p> <div style="box-sizing:border-box;color:rgb(96, 96, 96);font-size:15px;line-height:20px;margin-bottom:3rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p> <figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:0px;height:auto;background-color:rgb(232, 237, 243) !important;"> <div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"> <img style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" title="Analissa Cox" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/ghhs-2020-cox.jpg" data-entity-uuid="e60ff57f-69e3-4a5c-ab02-e213de1e2c6e" data-entity-type="file" class="img-fluid" alt="Analissa Cox" /> </div> <figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"> <em style="box-sizing:border-box;">Analissa Cox</em> </figcaption> </figure>Twelve fourth-year medical students and two faculty members from the University of Arizona College of Medicine – Phoenix were inducted into the <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/ghhs" target="_blank">Gold Humanism Honor Society</a> (GHHS) on Nov. 10 during a virtual ceremony. These individuals were selected for their demonstration of professionalism, leadership and humanism.<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“These students have been selected by their peers as exemplars of humanism,” said <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/dean-reed" target="_blank">Guy Reed, MD, MS</a>, dean of the College of Medicine – Phoenix. “Being inducted into the Gold Humanism Honor Society is an acknowledgment from fellow students and from faculty that these individuals have shown their commitment to the honor society’s values, which are to inspire, to nurture and to be life long advocates for compassionate patient care.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The exemplary students inducted this year include:</p><p style="box-sizing:border-box;margin:0px auto 1rem;" class="align-center"><span style="box-sizing:border-box;"><img class="" style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/ghhs-2020-inductees.png" alt="The 2020 GHHS Inductees" /><span style="box-sizing:border-box;">​</span></span></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">In addition, the students selected two faculty inductees into the College of Medicine – Phoenix GHHS this year. These two faculty inductees exemplify humanistic qualities and have served as role models for the students.</p><ul style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><li style="box-sizing:border-box;">Jennifer Hartmark-Hill, MD.</li><li style="box-sizing:border-box;">Robert Raschke, MD.</li></ul><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><figure class="bg-light figure img-fluid align-left" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 1rem 1rem 0px;float:left;max-width:0px;height:auto;background-color:rgb(232, 237, 243) !important;"><div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"><img style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" title="Nicole Segaline" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/ghhs-2020-segaline.jpg" data-entity-uuid="f7b91869-2070-4eb1-bff3-4710d95f253d" data-entity-type="file" class="img-fluid" alt="Nicole Segaline" /></div><figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"><em style="box-sizing:border-box;">Nicole Segaline</em></figcaption></figure>Traditionally, each student receives their GHHS pin and adds a knot to their distinctive class ribbon attached to the Staff of Asclepius. The staff commemorates the chapter’s inaugural class. Each knot that is added lengthens the respective chains, stretching the bond between the members of the society and symbolizing power, strength and compassion. Due to the pandemic, each student tied their knot prior to the ceremony.<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Natasha Keric, MD, an associate professor in the <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/surgery" target="_blank">Department of Surgery</a>, was the keynote speaker. Dr. Keric, who is also the surgery clerkship director, discussed the importance of mentorship.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“Out of all the hats that I get to wear, being a mentor is probably one of my favorite hats,” Dr. Keric said. “It brings tremendous joy to my professional career and personal life. The reason is that without mentorship, I wouldn’t be where I am today.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Dr. Keric shared parts of her personal journey and path toward medicine. Her story included immigrating to the U.S. at a young age, her love for education, a career outside of medicine, finding her true calling and the mentors that helped her excel in life.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“Mentors come in all shapes and sizes,” Dr. Keric said. “Being a mentor is not just rooting for somebody on the sidelines. It is becoming a part of their journey.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:0px;height:auto;background-color:rgb(232, 237, 243) !important;"><div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"><img style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" title="Jenna Koblinski" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/ghhs-2020-koblinski.jpg" data-entity-uuid="ab4be28b-47da-4152-a260-bcd6efdee61e" data-entity-type="file" class="img-fluid" alt="Jenna Koblinski" /></div><figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"><em style="box-sizing:border-box;">Jenna Koblinski</em></figcaption></figure>She continued, “It is incredibly rewarding to see how mentorship has helped us come together as a community and as a family. I am proud of my journey, not because of the success it has brought me, but because it has given me the tools to make others successful, which is truly very joyous and rewarding.”<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The College of Medicine – Phoenix GHHS chapter was established in 2010 and each year, the top 10-15 percent of the third-year medical students are identified by their peers as exemplars of humanism in medicine.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Members have a responsibility to model, support and advocate for compassionate, patient-centered care throughout their careers. The creation of a GHHS chapter signifies to the medical community that an institution places high value on the interpersonal skills and attitudes that are essential for the highest level of patient care.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“One of the things I always try to promote among students is deciding what kind of doctor they want to be,” said <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/academic-affairs/lieberman" target="_blank">Steven A. Lieberman, MD</a>, senior associate dean of Academic Affairs. “How do you represent yourself as a human that is a physician to your patients and the world around you? The Gold Humanism Honor Society is the culmination, perhaps the single, best honor to represent the true values of the profession. We look to all of you to continue to represent those standards that you all have demonstrated so clearly.”​<br></p></div> <p> <br> </p> </html></div>2020-12-09T07:00:00ZUA
Event: Sign up for virtual tours of TGen October 20, 2020; November 18, 2020 and December 11, 2020 Event: Sign up for virtual tours of TGen October 20, 2020; November 18, 2020 and December 11, 2020<div class="ExternalClass288A625BAF884F1CADFFA7AD172DED18"><html> <p>​<span id="ms-rterangepaste-start"></span><strong>Event: </strong><a target="_blank" href="https://www.tgen.org/education/tour-tgen/"><strong>Sign up for virtual tours of TGen October 20, 2020; November 18, 2020 and December 11, 2020</strong></a><strong> </strong>View the next generation sequencing technology and biomedical research laboratories where TGen scientists unlock the mysteries of cancer, diabetes, rare and neurological disease.​<span id="ms-rterangepaste-end"></span><br></p> </html></div>2020-12-08T07:00:00ZTGen
OncoMyx Announces Assignment of Foundational Technology and Intellectual Property Portfolio for Oncolytic Myxoma Virus TechnologyOncoMyx Announces Assignment of Foundational Technology and Intellectual Property Portfolio for Oncolytic Myxoma Virus Technology<div class="ExternalClass2CEEFE050B3B4F4FB1453EAB1302A390"><html> <p>​</p> <span id="ms-rterangepaste-start"></span> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);">PHOENIX--(<span><span><a style="color:rgb(121, 162, 189);outline:none;" href="https://www.businesswire.com/" rel="nofollow" target="_blank">BUSINESS WIRE</a></span></span>)--<a style="color:rgb(121, 162, 189);outline:none;" shape="rect" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&url=https://oncomyx.wpengine.com/&esheet=52340961&newsitemid=20201207005005&lan=en-US&anchor=OncoMyx+Therapeutics&index=1&md5=5d30c9d2277076d6ee10d2f4413eea6c" target="_blank">OncoMyx Therapeutics</a>, a privately-held oncolytic immunotherapy company, announced today that The University of Western Ontario (Western) has assigned to OncoMyx the technology and patent rights associated with pioneering research on the use of myxoma virus in the treatment of cancer. This research was led by OncoMyx cofounder Grant McFadden, Ph.D., when he was a Professor at Western and the Robarts Research Institute.</p> <blockquote style="margin:5px 15px 15px 0px;font-stretch:normal;font-size:1.2857em;line-height:1.1667em;font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;color:rgb(122, 165, 42);float:left;top:-0.0833em;width:386.797px;background-color:rgb(254, 254, 254);border-right:1px solid rgb(122, 165, 42) !important;"> <p style="margin:4px 0px;font-size:18px;line-height:26px;padding-right:12px;">“The myxoma virus has a number of important attributes that we are leveraging to develop potentially impactful oncolytic immunotherapies with the goal of increasing the number of cancer patients who could benefit from immunotherapies.”</p> <a style="color:rgb(121, 162, 189);float:left;font-size:16px;margin:10px 0px;padding:3px 3px 3px 28px;border:none;outline:none medium !important;" href="https://www.businesswire.com/news/home/20201207005005/en/OncoMyx-Announces-Assignment-of-Foundational-Technology-and-Intellectual-Property-Portfolio-for-Oncolytic-Myxoma-Virus-Technology#" target="_blank">Tweet this</a> </blockquote> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);">Lisa Cechetto, the Executive Director of WORLDiscoveries<span style="font-size:12px;line-height:0;vertical-align:baseline;top:-0.5em;">TM</span>, the technology transfer office for Western, Robarts Research Institute, and Lawson Research Institute, said, “We are pleased to assign these patents to OncoMyx, as it is important that the outputs of pioneering research, such as Dr. McFadden’s use of myxoma virus to create novel oncolytic therapies, be further developed to improve the lives of cancer patients or others who may benefit.”</p> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);">“The assignment of this technology and intellectual property to OncoMyx further reinforces our IP portfolio protecting our use of myxoma virus and our pipeline of myxoma virotherapies for the treatment of cancer,” said Steve Potts, Ph.D., MBA, cofounder and chief executive officer of OncoMyx. “The myxoma virus has a number of important attributes that we are leveraging to develop potentially impactful oncolytic immunotherapies with the goal of increasing the number of cancer patients who could benefit from immunotherapies.”</p> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);">“Oncolytic viruses are emerging as a new pillar of cancer care with the potential to expand the effectiveness of immunotherapies, such as immune checkpoint inhibitors,” said Dr. McFadden. “I am pleased that OncoMyx has been assigned the patent rights associated with the pioneering myxoma research that was done at Western, as the myxoma virus is unique as a technology platform to build oncolytic immunotherapies.”</p> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);"> <strong>About Myxoma Virotherapy for the Treatment of Cancer</strong> </p> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);">The myxoma virus is highly immuno-interactive and can selectively infect and kill a broad range of cancer cell types. Because myxoma virus is not pathogenic to humans, myxoma virotherapy does not have to overcome pre-existing immunity. As a large dsDNA poxvirus, myxoma is engineerable to express multiple transgenic payloads, such as immunomodulatory proteins, to target multiple points in the cancer immunity cycle. The company’s preclinical data demonstrates efficacy of multi-armed myxoma virotherapies via intravenous (IV) and intratumoral (IT) delivery in a number of tumor models across multiple cancer indications and supports a pan-tumor approach to expand the therapeutic effectiveness of immunotherapies.</p> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);"> <strong>About OncoMyx Therapeutics</strong> </p> <p style="margin:0px 0px 1.5em;color:rgb(68, 68, 68);font-family:"helvetica neue", helvetica, arial, "lucida grande", sans-serif;font-size:16px;background-color:rgb(254, 254, 254);">OncoMyx Therapeutics develops oncolytic immunotherapies based on the myxoma virus (MYXV) platform to orchestrate an immune response to better treat cancer. Successful immuno-oncology (IO) cancer treatment generally requires combination therapy, and oncolytic viruses (OVs) have the potential to be a safe and effective complement to immunotherapies. The company’s MYXV platform, exclusively licensed from Arizona State University and Western, is poised to be a best-in-class OV approach, and the top OV team has assembled around MYXV to create important new therapeutic options for cancer patients. For more information, please visit <a style="color:rgb(121, 162, 189);outline:none;" shape="rect" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&url=http://www.oncomyx.com&esheet=52340961&newsitemid=20201207005005&lan=en-US&anchor=www.oncomyx.com&index=2&md5=9205585419f67f571ec483e46c26b6f6" target="_blank">www.oncomyx.com</a> and connect with the company on <a style="color:rgb(121, 162, 189);outline:none;" shape="rect" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&url=https://www.linkedin.com/company/oncomyx&esheet=52340961&newsitemid=20201207005005&lan=en-US&anchor=LinkedIn&index=3&md5=4da727172185fe063e8ac36aa5803ea4" target="_blank">LinkedIn</a> and <a style="color:rgb(121, 162, 189);outline:none;" shape="rect" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&url=https://twitter.com/oncomyx&esheet=52340961&newsitemid=20201207005005&lan=en-US&anchor=Twitter&index=4&md5=d7e0b625f1d050e6936ba58e575486e9" target="_blank">Twitter</a>.​<br></p> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>2020-12-07T07:00:00ZOncoMyx Therapeutics
Researchers Awarded $8 Million Grant to Study Depression and Cardiovascular DiseaseResearchers Awarded $8 Million Grant to Study Depression and Cardiovascular Disease<div class="ExternalClass2E38D5A09BCA4A489840A732A294F0DD"><html> <div> <h5 style="box-sizing:border-box;margin-top:0px;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";line-height:18px;color:rgb(155, 155, 155);font-size:15px;margin-bottom:0px !important;margin-right:0.5rem !important;text-transform:uppercase !important;" class="field_title text-uppercase mb-0 mr-2"> <span style="box-sizing:border-box;" class="field field--name-title field--type-string field--label-hidden">​TERESA JOSEPH</span> </h5> <div> <span style="box-sizing:border-box;" class="field field--name-title field--type-string field--label-hidden"> <br> </span> </div> <a style="box-sizing:border-box;color:rgb(1, 28, 72);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:16px;" href="https://twitter.com/uazmedphx/" target="_blank" class="field_media_contact_twitter_url"></a> <br> </div> <p> <br> </p> <div style="box-sizing:border-box;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;font-size:1.25rem;color:rgb(33, 33, 33) !important;" class="field field--name-field-subtitle field--type-string field--label-hidden h5 mb-lg-3 text-dark field__item">Collaborative Research Project with Massachusetts General Hospital-Harvard Medical School, Colorado State University and University of Arizona Receives Grant from NIH</div> <div style="box-sizing:border-box;color:rgb(96, 96, 96);font-size:15px;line-height:20px;margin-bottom:3rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Researchers are trying to better understand the sex differences of one of the primary causes of disability worldwide, the co-occurrence of major depression and cardiovascular disease. Major depression is common in people who suffer a major cardiac event, affecting up to 40 percent of such patients, according to studies.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">A collaborative research award examining this between Massachusetts General Hospital, Harvard School of Public Health, Colorado State University and the University of Arizona College of Medicine – Phoenix received an $8 million specialized center grant for research on sex differences (SCORE) from the National Institutes of Health (NIH) Office for Research on Women’s Health and the National Institute of Mental Health. About $1 million is earmarked for research to be conducted at the UArizona College of Medicine – Phoenix.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"> <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/directory/hale-taben" target="_blank">Taben Hale, PhD</a>, an associate professor in the <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/bms" target="_blank">Department of Basic Medical Sciences</a> at the College of Medicine – Phoenix, is a co-investigator on the project, which is led by co-principal investigators <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://cnl-sd.mgh.harvard.edu/?page_id=225" target="_blank">Jill Goldstein, PhD</a>, a professor of psychiatry and medicine and executive director of the Innovation Center on Sex Differences in Medicine at Massachusetts General Hospital and Harvard Medical School, and <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://phoenixmed.arizona.edu/bms/faculty/handa" target="_blank">Robert Handa, PhD</a>, a professor in Biomedical Sciences at Colorado State University and the UArizona College of Medicine – Phoenix.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p> <figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:0px;height:auto;background-color:rgb(232, 237, 243) !important;"> <div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"> <img style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" title="Taben Hale, PhD, and team" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/hale-research-story_0.jpg" data-entity-uuid="46870a50-65e2-46b5-8565-c2bd336f56a6" data-entity-type="file" class="img-fluid" alt="Taben Hale, PhD, and team" /> </div> <figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"> <em style="box-sizing:border-box;">Taben Hale, PhD, and team</em> </figcaption> </figure>“Heart disease is the leading cause of death in women — many of whom also have unrecognized or untreated major depressive disorder, or MDD,” Dr. Hale said. “MDD is among the top two, along with heart disease, primary causes of disability worldwide, and women have twice the risk of the co-occurrence of MDD with cardiovascular disease compared to men. Identifying a novel therapeutic strategy for these conditions would have significant impact on both lifespan and quality of life. These studies are focusing on changes that may be occurring during fetal development that may set the stage for future disease in adulthood. Understanding the long-term consequences of prenatal stress is particularly important right now given the increased stress that everyone is experiencing.”<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The NIH grant will fund three integrated studies that include:</p><ul style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><li style="box-sizing:border-box;">A population-level clinical neuroscience study relating prenatal stress and immune biomarkers to sex differences in brain circuitry and physiologic deficits in response to stress in MDD in early midlife.</li><li style="box-sizing:border-box;">Testing a novel therapeutic device to target the central nervous system’s control of mood and autonomic nervous system, which regulates bodily functions like heart rate, and associated physiology to reduce these sex-dependent deficits in MDD.</li><li style="box-sizing:border-box;">Experimental studies that will identify the mechanistic pathways in the brain involved in projects one and two.</li></ul><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The first two projects will be performed at Massachusetts General Hospital under the leadership of Dr. Goldstein, Ronald Garcia, MD, PhD, and Vitaly Napadow, PhD. The third project is directed by Dr. Handa, and the work will be performed at Colorado State University and UArizona College of Medicine – Phoenix in the laboratory of Dr. Hale.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The specific work at UArizona is to evaluate the impact of prenatal stress on regulation of blood pressure and heart rate, as well as behavioral function. Assessments will evaluate the impact of prenatal glucocorticoid exposure on behaviors that are suggestive of anxiety and depression. Glucocorticoids, including cortisol, are hormones that are increased in response to stress. UArizona researchers also will evaluate the potential therapeutic efficacy of transcutaneous vagal nerve stimulation — involving regular, mild pulses of electrical energy sent to the brain via a branch of the vagus nerve accessible in the outer ear — to reverse these effects.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“The scientific mission of this SCORE grant is to identify abnormalities, beginning in fetal development, that have shared consequences for sex differences in brain circuitry regulating mood, lifelong recurrence of MDD, hormonal imbalance, immune responses to stress, and autonomic and neurovascular dysfunction in early midlife and target these abnormalities using a novel neuromodulation technique,” Dr. Goldstein said. “The goal of this SCORE is to enhance our understanding of sex on MDD and translate this knowledge into sex-selective treatment strategies.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">According to researchers, MDD is associated with abnormalities in the stress response areas of the brain. These brain regions also regulate the autonomic nervous system, which is involved in the short-term regulation of blood pressure and heart rate. Dysregulation of the autonomic nervous system is associated with cardiovascular disease. In fact, women are at twice the risk for the co-occurrence of MDD, autonomic dysregulation and heart disease, leading to a 3-5-fold risk of death in women from heart disease, often with unrecognized and untreated MDD.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“This funding is critical to perform studies to advance our knowledge of the relationships between disorders of the brain and the heart, and to identify novel treatment strategies to specifically target cardiovascular disease and MDD,” Dr. Hale said.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><em>Grant Number: NIH U54 MH118919. The Innovation Center on Sex Differences in Medicine at Massachusetts General Hospital is the primary site under Dr. Goldstein’s leadership. The total costs awarded are $8,130,603, with $1,005,425 awarded to Dr. Hale’s team.</em></p></div> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/123/hale-research-feature.jpg2020-11-30T07:00:00ZUA
TGEN’S AND CITY OF HOPE’S DR. DANIEL D. VON HOFF WILL RECEIVE INAUGURAL AACR SCIENTIFIC ACHIEVEMENT AWARDTGEN’S AND CITY OF HOPE’S DR. DANIEL D. VON HOFF WILL RECEIVE INAUGURAL AACR SCIENTIFIC ACHIEVEMENT AWARD<div class="ExternalClass66750ADBA7A842B4A3A01CD9A0DD955C"><html> <p>​<span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;box-sizing:border-box;border-radius:0px;">Written by</span><span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;"> </span><span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;box-sizing:border-box;border-radius:0px;" class="uBlogsy_author_name"><a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;" title="Steve Yozwiak" href="https://www.tgen.org/news/?author=Steve+Yozwiak" target="_blank">Steve Yozwiak</a>​</span></p> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;float:left;width:855px;" class="col-md-12"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <em style="box-sizing:border-box;border-radius:0px;">AACR establishes award in honor of Dr. Von Hoff for his groundbreaking accomplishments as a dedicated and inspirational educator and for his sustained scientific innovation</em> </p> </div> </div> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;float:left;width:855px;" class="col-md-12"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">PHOENIX, Ariz., and DUARTE, Calif. — Nov. 24, 2020 —</span> The American Association for Cancer Research (AACR) announced today that <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/faculty-profiles/daniel-von-hoff/" target="_blank">Dr. Daniel D. Von Hoff</a> — a Distinguished Professor at the <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/" target="_blank">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.cityofhope.org/homepage" target="_blank">City of Hope</a> — will receive the inaugural AACR Daniel D. Von Hoff Award for Outstanding Contributions to Education and Training in Cancer Research.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Von Hoff, M.D., F.A.C.P., F.A.S.C.O., F.A.A.C.R, is being recognized for his groundbreaking accomplishments as a dedicated and inspirational educator, for his sustained scientific innovation that has accelerated advances in cancer science and medicine, and for his extraordinary contributions to the education and training of thousands of clinical cancer investigators. </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">His personal tutelage and professional guidance of young clinical fellows and junior clinical faculty for more than two decades have contributed not only to their educational background and training, but also to their ability to apply the principles learned to improve the care of countless cancer patients around the world. Future awards will be presented to deserving individuals who have made significant contributions to the education and training of cancer scientists and physicians at any career level and in any area of cancer research.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Von Hoff is also a Distinguished Professor in the Department of Medical Oncology and Therapeutic Research at City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases; the Virginia G. Piper Distinguished Chair for Innovative Cancer Research at HonorHealth Clinical Research Institute; Chief Scientific Officer for US Oncology Research; and Professor of Medicine at the University of Arizona and Mayo Clinic in Arizona.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">An internationally renowned cancer researcher, Dr. Von Hoff has contributed to the discovery and development of many approved anticancer therapeutics that are used routinely in the treatment of numerous types of cancer. These therapeutics include, but are not limited to, dexrazoxane, docetaxel, fludarabine, gemcitabine, irinotecan, mitoxantrone, nab-paclitaxel, paclitaxel, topotecan, vismodegib, pexidartinib, and nanoliposomal irinotecan. Notably, his work involving gemcitabine and nab-paclitaxel combination therapy in pancreatic cancer patients was one of the first to demonstrate improved response rates, progression-free survival, and overall survival in patients with metastatic pancreatic cancer.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">In addition to his scientific leadership, Dr. Von Hoff has long been a champion and mentor of early-career and early-stage investigators and is dedicated to supporting the professional development of the cancer research workforce. Importantly, Dr. Von Hoff is revered for conceptualizing the <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/news/2019/march/26/tgens-dr-von-hoff-recognized-by-the-aacr/?search=AACR" target="_blank">AACR/ASCO Methods in Clinical Cancer Research Workshop</a> and for establishing and guiding the development of the course. As such, the course has become the premier workshop dedicated to educating clinical fellows and junior faculty clinical researchers in oncology specialties in the principles of effective clinical trial designs and therapeutic interventions for the treatment of cancer. Since its inception in 1996, the workshop has trained more than 2,400 investigators to execute optimally designed clinical research studies. The concept of this workshop has also been globally adapted to similar workshops in Europe as well as Australia, which has drawn attendance from individuals from India, New Zealand, Pakistan, and many other countries within Southeast Asia. Collectively, more than 4,400 young clinical investigators have been trained through these workshops.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“The AACR is thrilled to establish an award to honor Dr. Von Hoff’s exceptional contributions to the training of cancer investigators,” said Margaret Foti, Ph.D., M.D., chief executive officer of the AACR. “Because of Dr. Von Hoff’s foresight and efforts, thousands of early-career cancer investigators around the world have received training in the fundamentals of clinical cancer research and clinical trial design. These individuals have since saved countless lives. The AACR is deeply grateful to Dr. Von Hoff for his unwavering commitment to ensuring the success of the AACR/ASCO Methods in Clinical Cancer Research Workshop for the benefit of cancer patients worldwide, and we are delighted that he will be celebrated as the inaugural recipient of this prestigious new award created in his name.” </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“I am humbled and deeply grateful for this very special honor,” said Dr. Von Hoff. "I share this honor with my incredible colleagues and teachers, who have devoted many thousands of hours to training and mentoring the next generation of clinical investigators. Our goal together has always been to make sure patients would only be asked to participate in well-designed clinical trials, which would answer important questions impacting patient care.” </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/faculty-profiles/jeffrey-trent/" target="_blank">Dr. Jeffrey Trent</a>, TGen President and Research Director, said: “I can think of no one more deserving of AACR’s recognition than Dr. Von Hoff. His tremendous achievements over the decades are a direct result of his unrelenting pursuit of new therapeutics guided by a drive to provide the absolute best care possible for our patients.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Steven Rosen, provost and chief scientific officer at City of Hope, said: “City of Hope’s alliance with TGen brings together brilliant scientists like Dr. Von Hoff. Together, we are training the next generation of scientists how to conduct well-designed clinical trials so that the personalized, precise treatments of tomorrow can be offered to patients who need them today.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">The award is accompanied by an honorarium and a featured award lecture to be held in conjunction with the AACR Annual Meeting 2021.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Von Hoff has been a member of the AACR since 1977 and was inducted into the inaugural class of Fellows of the AACR Academy in 2013. He served with distinction as AACR President from 1999-2000. In addition, Dr. Von Hoff served as a member of the AACR’s Executive Committee from 1998-2001, and as a member of the AACR Board of Directors from 1993-1996. Dr. Von Hoff served as a member of the AACR Council of Scientific Advisors in 2006, and was a trustee of the AACR Foundation from 2006-2014. He was the founding editor-in-chief of the AACR journal <em style="box-sizing:border-box;border-radius:0px;">Molecular Cancer Therapeutics</em> from 2001-2011 and a member of the editorial boards of additional AACR journals: <em style="box-sizing:border-box;border-radius:0px;">Clinical Cancer Research</em> (2000-2005) and <em style="box-sizing:border-box;border-radius:0px;">Cancer Research </em>(1995-2000). Dr. Von Hoff served as chair for the AACR Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research Committee (2007-2008; 2015-2016) and as a member of the committee from 2008-2009. He also served as chair for the PanCAN-AACR Innovative Grants Committee (2009-2010), and as co-chair of the AACR Annual Meeting Program Committee (2003-2004). Additionally, he was a member of a multitude of other committees, including: the AACR Clinical Trials Committee (2011-2012); AACR Clinical and Translational Cancer Research Committee (2009-2013); AACR Nominating Committee (2003-2004); AACR Annual Meeting Education Committee (2002-2003); AACR Richard and Hinda Rosenthal Memorial Award Committee (2001-2002); AACR Bruce F. Cain Memorial Award Committee (2000-2001); and the AACR Finance and Audit Committee (1998-2000).</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Von Hoff has been recognized by the AACR for his many cancer research accomplishments, earning an AACR Distinguished Public Service Award (2019) and the AACR Richard and Hinda Rosenthal Memorial Award (1997). His other distinguished awards include: the Bernard Fisher Lectureship from the University of Pittsburgh (2018); Merrill J. Egorin Outstanding Mentor of the Year Award (2018); Gold Medal for Excellence in Clinical Medicine from the Columbia University College of Physicians and Surgeons (2017); Giants of Cancer Care from OncLive (2016); Researcher of the Year from AZ Business Magazine (2015); Lori Groetken Memorial Lecture and Award from Washington University (2012); Scripps Genomic Medicine Award – Pioneering Implementation of Discoveries (2011); David A. Karnofsky Memorial Award, American Society of Clinical Oncology (2010); SU2C Pancreatic Dream Team: Cutting off the Fuel Supply, A New Approach to the Treatment of Pancreatic Cancer (2009-2017); SU2C-Cancer Research UK-Lustgarten Foundation Pancreatic Cancer Dream Team: Reprogramming of Transcriptional Circuitry to Control Pancreatic Cancer (2016-2020); William F. McWhorter Community Service Leader of the Year Award (2008); and Weinberg Award from the Dana-Farber Cancer Institute (2003). Dr. Von Hoff served on the National Cancer Advisory Board from 2004-2011. He was elected as a Fellow of the American Association for the Advancement of Science (1992), and Fellow of the American College of Physicians (1980). He was also the director of the Arizona Cancer Center at the University of Arizona (1999-2003); and professor and director of the Institute for Drug Development at the University of Texas Health Science Center at San Antonio (1989-1999).</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Von Hoff has published 741 papers, 143 book chapters, and over 1,186 abstracts during his prestigious career.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Von Hoff earned his medical degree from Columbia University College of Physicians and Surgeons. He earned his undergraduate degree from Carroll College.<br></p> </div> </div> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/118/dr_daniel_von_hoff.jpg2020-11-24T07:00:00ZTGen
PBC TODAYPBC TODAY<div class="ExternalClassDCE7E0A2106F46F183BF6A47961697E0"><html> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text">​<div class="text-container galileo-ap-content-editor"><div align="left"><span style="font-size:11px;color:rgb(83, 102, 127);font-style:italic;font-weight:bold;">An Update on the People, Places, and Possibilities of the Phoenix Biomedical Campus in Downtown Phoenix • Oversight provided by Arizona State University (Michael Crow, President), Northern Arizona University (Rita Cheng, President), University of Arizona (Robert Robbins, President), Arizona Board of Regents (John Arnold, Executive Director), and City of Phoenix led by Mayor Kate Gallego</span></div><div align="left"><br>​<br></div><div align="left"><span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">850 N. 5th Street building now available for tours</span></div><div align="left"><span style="font-size:11px;color:rgb(0, 0, 0);">After years of visioning, planning, and construction, 850 N. 5th Street is available for tours. The building is a collaborative effort between the City of Phoenix, Arizona State University, and Wexford Science & Technology, LLC. Totaling 227,000 SF with 100,000 SF of commercial lab or office space on the top three floors above Arizona State University research and innovation and GateWay Community College's Center for Entrepreneurial Innovation. 850 N. 5th Street will be a gathering hub for life science and biomedical innovation. The building is part of ongoing expansion on the Phoenix Biomedical Campus, connecting the downtown biomedical campus to the Evans Churchill Neighborhood and Roosevelt Row Arts District. Designed to integrate research, entrepreneurial activity, and corporate engagement, 850 N. 5th Street serves as a bridge between the surrounding neighborhoods, the academic community, and the professional community. The building's design purposefully invites the neighborhood to participate in its success through the first-floor program elements that are visually porous and accessible. A portion of the building will include turn-key lab space for private research, growing companies, or a soft-landing option for larger companies locating in Phoenix. To schedule a tour or receive information about available lease space, contact Kyle Jardine at 480-779-7181 or </span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:Kyle.Jardine@wexfordscitech.com">email</a><span style="font-size:15px;color:rgb(0, 0, 0);font-family:calibri, helvetica, arial, sans-serif;">.</span></div><div align="left"><br></div><div align="left"><span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Connect2STEM 2021 reimagined for 2021</span></div><div align="left"><span style="font-size:11px;color:rgb(0, 0, 0);">Register to attend the (free) 7th Annual Connect2STEM event on Saturday, January 30, 2021 starting at 10 a.m. There will be two ways for families to experience Connect2STEM 2021 – via the drive-through experience or Connect2STEM TV. Load up the car with your favorite STEM fans for a drive-through STEM experience. The entire family can enjoy fun activities while maintaining safe social distance. See live performances, visit discovery zones, and solve mysteries of science – and medicine throughout your drive. Due to space restrictions, limited tickets and time slots will be offered. Can't attend? Connect2STEM TV will be live throughout the day, showcasing some truly amazing STEM experiences for the whole family. For more information and to register, </span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://phoenixmed.arizona.edu/c2s">click here</a><span style="font-size:11px;color:rgb(0, 0, 0);">.</span></div><div align="left"><br></div><div align="left"><span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Take part in Friday’s ASU Biomedical Innovation Speaker Series</span></div><div align="left"><span style="font-size:11px;color:rgb(0, 0, 0);">Join Arizona State University and the Arizona Biomedical Research Center to hear top experts in the biomedical field. On tap for this Friday, November 20, 2020 from 11 a.m. to Noon is Thomas Osha, Senior Vice President of Innovation and Economic Development at Wexford Science and Technology, who will discuss how universities can leverage their research and technologies and collaborate across institutions and sectors to create knowledge-led economic development locally and globally. A big thank you to Dr. Susan Pepin for putting this series together. Here’s the </span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://asu.zoom.us/j/82073044607">Zoom link</a><span style="font-size:11px;color:rgb(0, 0, 0);"> for Friday’s talk (no pre-registration required).</span></div><div align="left"><br></div><div align="left"><span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Participate in UArizona’s Wellness Wednesdays</span></div><div align="left"><span style="font-size:11px;color:rgb(0, 0, 0);">The University of Arizona Health Sciences is holding “</span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://mailchi.mp/uahs.arizona.edu/wellness-wednesdays-celebrating-health-holiday">Wellness Wednesdays: A Community Connection</a><span style="font-size:11px;color:rgb(0, 0, 0);">,” a series of free virtual lunchtime events launched earlier this year to promote nutritious foods, healthy minds, and strong bodies. There are two more live Wellness Wednesday sessions this year: “Tai Chi for Health and Well-Being” on Nov. 18, and “Awareness Through Movement: Improving Your Health and Life Using the Feldenkrais Method” on Dec. 2. To register for these sessions, </span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://mailchi.mp/ahsc.arizona.edu/wellness-wednesdays">click here</a><span style="font-size:11px;color:rgb(0, 0, 0);">.</span></div><div align="left"><br></div><div align="left"><span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">City publishes new Phoenix Biomedical Campus brochure</span></div><div align="left"><span style="font-size:11px;color:rgb(0, 0, 0);">Take a peek at the new brochure for the Phoenix Biomedical Campus. Produced by the City of Phoenix, the brochure is available for download on the </span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="/Documents/Phoenix%20Biomedical%20Campus%202020.pdf">PBC website</a><span style="font-size:11px;color:rgb(0, 0, 0);"> and hard copies will be shared upon delivery. For more information, contact Claudia Whitehead via </span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:claudia.whitehead@phoenix.gov">email</a><span style="font-size:11px;color:rgb(0, 0, 0);">.</span></div><div align="left"><br></div><div align="left"><span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">NAU OT Virtual Open House set for Dec. 3.</span><span style="font-size:12px;color:rgb(83, 102, 127);"></span></div><div align="left"><span style="font-size:11px;color:rgb(0, 0, 0);">The next virtual open house for interested applicants to the Northern Arizona University Occupational Therapy (OT) program is Thursday, December 3, 2020. To register to attend, </span><a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://nau.edu/occupational-therapy/">click here</a><span style="font-size:11px;color:rgb(0, 0, 0);">.</span></div></div><br></td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PEOPLE </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Noteworthy individuals making a difference</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="/news-events/110">OncoMyx Therapeutics appoints Dr. Charles Baum as board chair</a> (OncoMyx Therapeutics, 11-06-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://chs.asu.edu/news/feeling-down-grab-boost-some-water">ASU Hydration Science Lab Director Stavros Kavouras finds link between dehydration, mood in latest study</a> (ASU College of Health Solutions, 11-05-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="/news-events/107">Dr. Ziad Obermeyer discusses opportunities and challenges of algorithms in healthcare at annual Buffmire Lecture</a> (Flinn Foundation, 10-27-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="/news-events/104">TGen appoints Dr. Sunil Sharma as physician-in-chief</a> (TGen, 10-27-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PLACES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Properties and new developments where good things happen</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://associationsnow.com/2020/11/the-future-of-meetings-find-out-how-specialized-cities-lend-themselves-to-specialized-meetings/">The future of meetings: how specialized cities lend themselves to specialized meetings</a> (Associations Now, 11-03-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://flinn.org/bioscience/resources/arizonas-bioscience-ecosystem/">Flinn Foundation publishes “new and improved” directory and map of bioscience businesses and organizations statewide</a> (Flinn Foundation, 11-01-20) </li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">POSSIBILITIES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Significant research & educational opportunities going on</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.paysonroundup.com/news/health/university-of-arizona-health-sciences-has-e-newsletter-program/article_619a271b-9ac3-5daf-81c4-f09f39534e1d.html">University of Arizona Health Sciences launches “Wellness Wednesdays: Celebrating Health & Holiday”</a> (Payson Roundup, 11-17-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://chs.asu.edu/news/defining-health-care-spending-waste-us">ASU College of Health Solutions researchers publish papers exploring health care spending waste</a> (ASU College of Health Solutions, 11-16-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.fiercebiotech.com/research/arming-rabbit-pox-virus-to-fight-cancer">Arming the rabbit pox virus to fight cancer</a> (OncoMyx Therapeutics, 11-12-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://nau.edu/cher/adrd-apha-award-2020/">SHERC researchers win APHA Rural and Environmental Research Award for work with family caregivers of individuals with Alzheimer’s disease and related dementias</a> (NAU, 10-22-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="/news-events/105">OncoMyx Therapeutics presents preclinical data for novel oncolytic virotherapy at AACR Tumor Immunology & Immunotherapy Virtual Conference</a> (OncoMyx Therapeutics, 10-19-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://asunow.asu.edu/20201015-new-edson-college-partnership-opens-doors-qualitative-research-around-recovery-and-exercise">New Edson College partnership opens doors for qualitative research around recovery and exercise</a> (ASU Edson College of Nursing and Health Innovation, 10-15-20)</li> </ul> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);"></span> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://asunow.asu.edu/20200714-arizona-impact-asu-acts-fast-help-nurses-transition-icu">ASU acts fast to help nurses transition to ICU</a> (ASU Edson College of Nursing and Health Innovation, 07-14-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PARTICULARS</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="" width="100%" class=" editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text editor-text "> <div></div> <div class="text-container galileo-ap-content-editor"> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Contact:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <span style="font-size:12px;color:rgb(0, 0, 0);">David Krietor, Executive Director, 602-741-5580, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:david.krietor@asu.edu">david.krietor@asu.edu</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Website:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://urldefense.proofpoint.com/v2/url?u=https-3A__biomedicalphoenix.com_&d=DwMFaQ&c=l45AxH-kUV29SRQusp9vYR0n1GycN4_2jInuKy6zbqQ&r=ZkOduS1eiLUbvWLZ-8ug9vL9jHDR32Y_z26zPsk2vak&m=-wKoE3rm1i95DXGiQyqWJla6ia5YA9fsFMAO4vC9trM&s=XmoGrKj6ux3_Hjm5HLDxe1wzR5CGHEalThzpBkYVG90&e=">biomedicalphoenix.com</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:claudia.whitehead@phoenix.gov">Claudia Whitehead</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" 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To subscribe or share news, send us an email.</span> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="left" width="100%" class="content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <span style="font-size:10px;color:rgb(83, 102, 127);font-weight:bold;">PBC </span> <span style="font-size:10px;color:rgb(235, 169, 66);font-weight:bold;">| </span> <span style="font-size:10px;color:rgb(83, 102, 127);font-weight:bold;">David Krietor, Executive Director</span> <span style="font-size:10px;color:rgb(235, 169, 66);font-weight:bold;"> |</span> <span style="font-size:10px;color:rgb(83, 102, 127);font-weight:bold;"> 602</span> <span style="font-size:10px;color:rgb(83, 102, 127);font-weight:bold;">-741-5880 </span> <span style="font-size:10px;color:rgb(235, 169, 66);font-weight:bold;">|</span> <span style="font-size:10px;color:rgb(83, 102, 127);font-weight:bold;"> </span> <a style="text-decoration-line:underline;font-size:10px;color:rgb(83, 102, 127);font-weight:bold;" target="_blank" rel="noopener noreferrer" href="mailto:david.krietor@asu.edu">david.krietor@asu.edu</a> <span style="font-size:10px;color:rgb(235, 169, 66);font-weight:bold;"> |</span> <span style="font-size:10px;color:rgb(83, 102, 127);font-weight:bold;"> biomedicalphoenix.com</span> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/115/Project-Hero-Image-PBC-1.jpg2020-11-19T07:00:00ZPhoenix Bio News
OncoMyx’s Oncolytic Virus Platform Shows Preclinical Efficacy, Boosting Immunotherapy PotentialOncoMyx’s Oncolytic Virus Platform Shows Preclinical Efficacy, Boosting Immunotherapy Potential<div class="ExternalClassD013439146D8484D8666F11737F01187"><html> <p>​</p> <span id="ms-rterangepaste-start"></span> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);"> <em style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font-variant:inherit;font-weight:inherit;font-stretch:inherit;font-size:inherit;line-height:inherit;font-family:inherit;">Myxoma virus with transgenes. Photo courtesy of OncoMyx.<span style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font-style:normal;font-weight:bold;font-stretch:inherit;font-size:15px;line-height:1.4;font-family:arial, sans-serif;color:rgb(102, 102, 102);"> </span></em> </p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Only about one in seven cancer patients today benefit from immunotherapy. <span style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font-style:inherit;font-variant:inherit;font-weight:700;font-stretch:inherit;font-size:inherit;line-height:inherit;font-family:inherit;"><a style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font:inherit;color:rgb(78, 112, 167);" href="https://www.oncomyx.com/" target="_blank">OncoMyx</a> </span>aims to increase this number, using a new multi-armed, systemically-administered, and targeted oncolytic virus. The company reported positive data in preclinical trials at the Society for Immunotherapy of Cancer’s (SITC) 35th Anniversary Annual Meeting & Preconference Programs <span style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font-style:inherit;font-variant:inherit;font-weight:700;font-stretch:inherit;font-size:inherit;line-height:inherit;font-family:inherit;">(<a style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font:inherit;color:rgb(78, 112, 167);" href="https://www.sitcancer.org/2020/home" target="_blank">SITC 2020</a>)</span>, which concluded November 14th.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">“Amgen showed an oncolytic virus could have an impact when<span style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font-style:inherit;font-variant:inherit;font-weight:700;font-stretch:inherit;font-size:inherit;line-height:inherit;font-family:inherit;"> <a style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font:inherit;color:rgb(78, 112, 167);" href="https://www.amgen.com/media/news-releases/2015/10/fda-approves-imlygic-talimogene-laherparepvec-as-first-oncolytic-viral-therapy-in-the-us/" target="_blank">IMLYGIC</a>,</span> its live herpes virus, was approved for intratumoral injection in 2015,” Steve Potts, Ph.D., co-founder and CEO of OncoMyx, told BioSpace. “Now the race is on to build a best-in-class, IV-delivered oncolytic immunotherapy solution.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">“Our approach uses myxoma, a large DNA rabbit pox virus,” he said. Myxoma replicates only in rabbits, thus enhancing its safety profile. When administered to humans, the OncoMyx lead compound, OM101, is expected to replicate only in tumor cells. It is intended to be delivered intravenously, systemically stimulating the immune system by releasing tumor antigen and promoting inflammation to turn cold tumors hot.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Myxoma also is one of very few oncolytic viruses capable of carrying an extra three-to-five immunostimulatory genes to further boost the immune response against cancer. “Adding transgenes can stimulate multiple points across the cancer immune response and can also be used to make this cancer-specific,” Potts said.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Unlike kinase inhibitor programs in targeted therapies that attack specific cancer genetic alterations, OncoMyx’s approach targets mechanisms of action. That means that OM101, can – in preclinical trials, at least – more broadly target multiple points across tumor types that are driven by a given mechanism of action. That enables the virus to target mechanisms that for example, a quarter of all cancer patients might share, rather than the typical one or two percent that might be shared by a genetic alteration approach in targeted therapies</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">“We can be very flexible and yet still have a targeted approach,” Potts said. “It’s designed for use in a broad range of patients.”</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);"> <span style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font-style:inherit;font-variant:inherit;font-weight:700;font-stretch:inherit;font-size:inherit;line-height:inherit;font-family:inherit;"> <a style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font:inherit;color:rgb(78, 112, 167);" href="https://www.oncomyx.com/wp-content/uploads/2020/11/OncoMyx-SITC-2020-Abstract-409-FINAL.pdf" target="_blank">One preclinical study</a> </span> showed that the armed and parent versions of the virus were equally effective in terms re replication and oncolytic capacity, and that the multi-armed virus produced functional transgenes in Vero cells and in human lung cancer and cervical cancer cells.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);"> <span style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font-style:inherit;font-variant:inherit;font-weight:700;font-stretch:inherit;font-size:inherit;line-height:inherit;font-family:inherit;"> <a style="box-sizing:border-box;margin:0px;padding:0px;border:0px;font:inherit;color:rgb(78, 112, 167);" href="https://www.oncomyx.com/wp-content/uploads/2020/11/OncoMyx-SITC-2020-Abstract-406-FINAL.pdf" target="_blank">Another</a> </span>showed that the armed myxoma virus is efficacious with immune checkpoint inhibitors. The armed virus increased the anti-tumor tumor-infiltrating lymphocytes – including increased CD8/Treg and M1/M2 macrophage ratios – to favor anti-tumor immunity.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Based on myxoma’s method of replication and action, toxicity should be very limited. Likewise the risk of over-stimulating the immune system also appears minimal. “Because we’re working backward from the tumor cells, this is a very localized approach that generates a systemic effect,” he explained.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">As Leslie Sharp, Ph.D., CSO, elaborated, “We’ve done studies, including intratumoral and systemic injections, in mice and the virus is very well-tolerated. We’re looking forward to clinical trials.”</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Potts and Sharp expect OM101 to enter clinical trials within two years for solid tumors. Applications for various lines of therapy in a wide range of cancers will be investigated.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Additional therapies, notably OM102 and OM103, may be based on the OM101 platform. More tightly targeted, they are aimed at lung, gastrointestinal, and gynecologic cancers. By adding specific transgenes, “We end up with a very powerful approach,” Potts said</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Within the immunotherapy field, OncoMyx’s platform is the equivalent, he said, “of taking multiple single antibody programs and combining them into one. It offers lots of flexibility and a very elegant approach to thinking about multi-arming therapies.”</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">“In non-clinical models, we’ve looked at activity of the compound administered alone and in conjunction with checkpoint inhibitors,” Sharp said. “The virus is active on its own. In a number of tumor models it elicited complete responses. When combined with checkpoint inhibitors, the activity, in general, is greater, resulting in smaller tumors or longer survival.”</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">“These data support the further development of our multi-armed myxoma virotherapies in combination with checkpoint inhibitors and other immuno-oncology approaches to increase the number of cancer patients who could benefit from immunotherapies,” Potts said when announcing the data.</p> <p style="box-sizing:border-box;margin:0px 0px 0.8em;padding:0px;border:0px;font-stretch:inherit;font-size:1.15rem;line-height:1.7;font-family:"open sans", helvetica, arial, sans-serif;color:rgb(86, 86, 86);">Building on these preclinical results, OncoMyx is building its team and therapeutic pipeline, planning GMP manufacturing, and preparing for an IND application, and building its pipeline of the other armed targets as it seeks to raise its next round of financing.​<br></p> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/119/Virus.jpg2020-11-17T07:00:00ZOncoMyx Therapeutics
Arming the rabbit pox virus to fight cancerArming the rabbit pox virus to fight cancer<div class="ExternalClass015D30ECFD5A4FD09C0704B6FF6FF2A1"><html> <span style="font-size:17.3333px;">​Oncolytic viruses hold promise as cancer treatments due to their cancer-killing prowess and ability to be combined with other therapies. But few drugs derived from oncolytic viruses have made it to the market.</span><br style="font-size:17.3333px;"><br style="font-size:17.3333px;"><span style="font-size:17.3333px;">Arizona State University spinout OncoMyx Therapeutics is designing anti-cancer therapies from a type of rabbit pox virus called myxoma. The company has early data showing that the virus, when armed with relevant transgenes, can suppress different types of cancer in mice both as an injection directly into tumors and through systemic administration by intravenous infusion.</span><br style="font-size:17.3333px;"><br style="font-size:17.3333px;"><span style="font-size:17.3333px;">In mouse models of melanoma and bone cancer, the drug significantly slowed tumor growth, and it was even better at shrinking tumors and prolonging the animal’s lives when paired with a PD-1 or PD-L1 inhibitor, according to data presented at the Society for Immunotherapy of Cancer (SITC) virtual meeting.</span>​<br><span style="font-size:17.3333px;"> </span><span style="font-size:17.3333px;"></span><span style="font-size:17.3333px;"> </span><span id="ms-rterangepaste-start" style="font-size:17.3333px;"></span><span style="font-size:17.3333px;"> </span><p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;"><br></span></p><p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">“These data support the further development of our multi-armed myxoma virotherapies in combination with checkpoint inhibitors and other immuno-oncology approaches to increase the number of cancer patients who could benefit from immunotherapies,” Steve Potts, Ph.D., co-founder and CEO of OncoMyx, </span><a style="box-sizing:inherit;color:rgb(237, 28, 38);font-weight:bold;" rel="nofollow" href="https://www.oncomyx.com/oncomyx-announces-presentation-of-preclinical-efficacy-data-of-novel-oncolytic-immunotherapy-at-sitc-2020/" target="_blank"><span style="font-size:17.3333px;">said</span></a><span style="font-size:17.3333px;"> in a statement.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Myxoma virus, like many other oncolytic viruses, works by directly infecting cancer cells, causing them to die. This process also releases tumor antigens that can stimulate an immune response to the cancer. But myxoma virus can offer several advantages.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">First, the natural host of myxoma virus are rabbits, and it doesn’t cause disease in any other animals or in humans. This means that the virus can be systemically injected into people safely, and that it doesn’t have to overcome pre-existing immunity, which might otherwise kill it off before it could provide any therapeutic benefit.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">What’s more, as a large DNA virus, myxoma virus can serve as a vector to carry additional genes to target different facets of cancer immunity.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">OncoMyx researchers showed that myxoma virus can replicate with up to six genes transferred to it, and that the virus can effectively express transgenes. These multi-armed myxoma viruses inhibited cancer growth across a wide range of human tumor types in lab dishes as well as in mice bearing human tumor xenografts.<br style=""></span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">The team further tested myxoma viruses bearing up to three genes, or arms, in immunocompetent mice. One arm was a cytokine that modulates T cell and natural-killer cell activity and recruitment to the tumor, Leslie Sharp, chief scientific officer of OncoMyx, explained in an email to FierceBiotechResearch. A second arm remodels the tumor microenvironment and removes cancer cells' suppression of T-cell immunity. And the third arm is a proinflammatory agent.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Unedited viruses were able to slow the growth of some tumors, but the effects were clearly better when the genes were edited in. “As is typical for preclinical models, response varies by model, but generally gives dose-dependent changes in tumor growth inhibition in the range of 70% to 99% including tumor regression and complete responses,” Sharp said. Tumor suppression was observed following both intratumoral and intravenous delivery of the viruses, and it led to increased survival of the animals.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Moreover, myxoma virus generally did better when being paired with either a PD-1 or PD-L1 inhibiting drug. That was even the case in a melanoma model that’s known to be resistant to immune checkpoint inhibition, suggesting it could be used in combination therapy to further boost the anti-tumor response.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Further analysis showed that multi-armed myxoma increased the population of tumor-infiltrating immune cells; the ratio of CD8+ T cells and immune-suppressing regulatory T cells was higher, and so was the ratio between pro-inflammatory M1 macrophages and healing-supportive M2 macrophages.​<br style=""></span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Very few virus-based cancer treatments have made it to market, and the ones that did have their limitations.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Amgen’s FDA-approved melanoma therapy Imlygic, for example, uses a cancer-killing herpes virus, which is genetically edited to reduce its harm on noncancerous tissue. But it can’t completely prevent it from infecting healthy cells. Plus, it needs to be injected directly into melanoma tumors to achieve the best results and avoid toxicity. Oncorine, the world’s first commercial oncolytic virus product, approved in China in 2005 for the treatment of head and neck cancer, is based on an adenovirus that also goes through an attenuation step to limit its damage of healthy cells. Because both types of viruses can infect humans, therapies based on them must overcome pre-existing immunity.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Nevertheless, oncolytic viruses remain hot targets of cancer research. A team at City of Hope recently </span><a style="box-sizing:inherit;color:rgb(237, 28, 38);font-weight:bold;" href="https://www.fiercebiotech.com/research/virus-combo-makes-solid-tumors-vulnerable-to-car-t-attack-mice" target="_blank"><span style="font-size:17.3333px;">engineered</span></a><span style="font-size:17.3333px;"> an oncolytic virus to express the CD19 protein on solid tumor cells, thereby allowing them to be targetable by CD19-directed CAR-T cell therapies, which so far have only worked in some blood cancers.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">Researchers led by Astellas’ drug discovery unit </span><a style="box-sizing:inherit;color:rgb(237, 28, 38);font-weight:bold;" href="https://www.fiercebiotech.com/research/cancer-killing-virus-boosts-immuno-oncology-responses-mice-astellas-led-study" target="_blank"><span style="font-size:17.3333px;">used</span></a><span style="font-size:17.3333px;"> a vaccinia virus, another large DNA virus that also belongs to the poxvirus family, to carry two cytokines—IL-7 and IL-12—to stimulate an anti-cancer immune response. The therapy also appeared to work in synergy with anti-PD-1 or anti-CTLA-4 antibodies.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">With promising animal data, OncoMyx is now working on programs to enable a first-in-human clinical trial for its lead program, dubbed OM101. “We can focus on large unmet needs in major cancer areas, for example, lung, gastro-intestinal, gynecologic, etc., and then look at patients within these populations where the mechanisms of interest are driving their tumor growth and will be most likely to benefit from therapy,” Potts said.</span></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;"></p> <p style="box-sizing:inherit;color:rgb(51, 51, 51);font-family:overpass, sans-serif;" class="MsoNormal"><span style="font-size:17.3333px;">The company raised a $25 million series A funding round in 2019, led by Boehringer Ingelheim Venture Fund, Delos Capital and Xeraya Capital.​<br style=""></span></p><span style="font-size:17.3333px;"> </span><span id="ms-rterangepaste-end" style="font-size:17.3333px;"></span><span style="font-size:17.3333px;"> </span><p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/112/rabbit.jpg2020-11-12T07:00:00ZOncoMyx Therapeutics
Event: Cell and Gene Therapy - CMC Challenges and Mitigation Strategies Free webinar on November 11th at 10 a.m. PST Event: Cell and Gene Therapy - CMC Challenges and Mitigation Strategies Free webinar on November 11th at 10 a.m. PST <div class="ExternalClass10D6C0EBDE4342549586F863AEBF9BA7"><html> <p>​<span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">Chemistry, manufacturing, and controls (CMC) is an integral aspect of cell and gene therapy development. Cell and gene therapy development presents unique CMC challenges because of inherent properties such as shorter shelf life, variability in starting and ancillary materials, manufacturing and logistical complexities, and cost. FDA cell and gene therapy information requests often contain more CMC related inquiries than traditional products. In this webinar, experts from Cardinal Health Regulatory Sciences discuss CMC challenges and potential mitigation strategies illustrated through multiple case studies. Cell and gene therapy developers, research scientists, regulatory and legal professionals are all encouraged to attend.</span></p> <p> <span id="ms-rterangepaste-start"></span>​<span id="ms-rterangepaste-end"></span><br></p> <p> <em>Register here:</em> <em> </em> <a target="_blank" href="https://urldefense.com/v3/__https:/pages.questexnetwork.com/LS-Custom-Webinar-CardinalHealth-111120-116773_LandingPage.html?source=fb-listing&_ga=2.94241237.970585205.1603979996-1547069854.1603979996__%3b%21%21LkjWUF49MRd51_ry%21Ngkdi0porSQmHXAiePEODjsVWAF9YOwk53wmkG25sPGv7UKsfVGghbZUJarwGtICIm9Tjvw3KRI$">Cell and Gene Therapy – CMC Challenges and Mitigation Strategies [pages.questexnetwork.com]</a>. <br></p> <p> <br> </p> </html></div>2020-11-09T07:00:00ZPhoenix Bio News
OncoMyx Therapeutics Appoints Dr. Charles Baum Chairperson of Board of DirectorsOncoMyx Therapeutics Appoints Dr. Charles Baum Chairperson of Board of Directors<div class="ExternalClass0D9346B372E04256B630F2278D26C35B"><html> <p>​<span style="text-align:justify;background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">PHOENIX, November 6, 2020 – </span><a style="text-align:justify;background-color:window;font-family:inherit;font-size:10pt;" href="https://oncomyx.wpengine.com/" target="_blank">OncoMyx Therapeutics</a><span style="text-align:justify;background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">, a privately-held oncolytic immunotherapy company, today announced the appointment of Charles (Chuck) M. Baum, M.D., Ph.D., as chairperson of the company's board of directors. Dr. Baum is currently president and chief executive officer of Mirati Therapeutics, which develops novel therapeutics that target the genetic and immunologic drivers of cancer. He has more than 25 years of experience leading the clinical development of precision oncology drugs, including axitinib (Inlyta®), crizotinib (Xalkori®), sunitinib (Sutent®), and temozolomide (Temodar®).</span></p> <p style="text-align:justify;"> </p> <p style="text-align:justify;">“We cannot think of a better person to chair our board of directors than Chuck Baum, who led Mirati Therapeutics in building an impressive oncology therapeutics pipeline and a strong leadership team," said Steve Potts, Ph.D., MBA, cofounder and chief executive officer of OncoMyx. “Chuck is also a classically trained immunologist, who built one of the earliest immuno-oncology programs in pharma and has successfully developed several targeted cancer therapies through clinical trials to market. His guidance and expertise in the development of targeted cancer therapies will be very valuable as OncoMyx is preparing to advance into clinical trials our first multi-armed myxoma virotherapy for cancer with a novel precision medicine and pan-tumor treatment approach."</p> <p style="text-align:justify;"> </p> <p style="text-align:justify;">“OncoMyx has assembled the top oncolytic virus team with extensive experience in advancing targeted cancer treatments, immunotherapies, and virotherapies and successfully bringing new cancer drugs to market," said Dr. Baum. “Oncolytic viruses are an extremely promising therapeutic approach to expanding the patient population that can benefit from immunotherapies, and OncoMyx's myxoma platform has numerous best-in-class advantages for multi-armed, systemically-delivered oncolytic immunotherapies."</p> <p style="text-align:justify;"> </p> <p style="text-align:justify;">At Mirati, Dr. Baum built a world-class precision oncology leadership team, took the company public on Nasdaq, and focused the company on targeted development of receptor tyrosine kinase and histone deacetylase inhibitors in various cancers. Prior to joining Mirati in 2012, he was at Pfizer since 2003, serving in roles of increasing responsibility including as Senior Vice President for Biotherapeutic Clinical Research within Pfizer's Worldwide Research and Development division; Vice President and Head of Oncology Development; and Chief Medical Officer for Pfizer's Biotherapeutics and Bioinnovation Center. Dr. Baum serves on the board of directors the BCTG Acquisition Corp and is a member of the scientific advisory board for ALX Oncology. Dr. Baum served on the board of directors of Array BioPharma and Immunomedics until each company was acquired for $11 billion by Pfizer, Inc. and $21 billion by Gilead Sciences, Inc., respectively. He received his M.D. and Ph.D. in immunology from Washington University School of Medicine in St. Louis and completed his post-graduate training at Stanford University. Dr. Baum has published more than 50 peer-reviewed manuscripts and holds a number of patents and patent applications.</p> <p style="text-align:justify;"> <strong> </strong> </p> <p style="text-align:justify;"> <strong>About OncoMyx Therapeutics</strong> </p> <p style="text-align:justify;">OncoMyx Therapeutics develops oncolytic immunotherapies based on the myxoma virus (MYXV) platform to orchestrate an immune response to better treat cancer. Successful immuno-oncology (IO) cancer treatment generally requires combination therapy, and oncolytic viruses (OVs) have the potential to be a safe and effective complement to other immunotherapy approaches. The company's MYXV platform, exclusively licensed from Arizona State University, is poised to be a best-in-class OV approach, and the top OV team has assembled around MYXV to create important new therapeutic options for cancer patients. For more information, please visit <a href="http://www.oncomyx.com/" target="_blank">www.oncomyx.com</a> and connect with the company on <a href="https://www.linkedin.com/company/oncomyx" target="_blank">LinkedIn</a> and <a href="https://twitter.com/oncomyx" target="_blank">Twitter</a>.</p> <p style="text-align:justify;"> </p> <p style="text-align:justify;"> <strong>Corporate Contact: </strong>Michael G. Wood, Cofounder & COO, <a href="mailto:mw@oncomyx.com" target="_blank">mw@oncomyx.com</a></p> <p style="text-align:justify;"> </p> <p> <strong>Media Contact:</strong> Jessica Yingling, Ph.D., <a href="http://www.litldog.com/" target="_blank">Little Dog Communications Inc.</a>, <a href="mailto:jessica@litldog.com" target="_blank">jessica@litldog.com</a> , +1.858.344.8091​<br></p> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/110/mirati0026.jpg2020-11-06T07:00:00ZOncoMyx Therapeutics
Event: Connect2STEM 2021 Reimagined! Saturday, January 30, 2021Event: Connect2STEM 2021 Reimagined! Saturday, January 30, 2021<div class="ExternalClass0F5791E4152045CE92B43741C4EDCFA1"><html> <p>​<span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">Register to attend the (free) 7</span><sup style="background-color:window;color:windowtext;font-family:inherit;">th</sup><span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;"> Annual Connect2STEM event on Saturday, January 30, 2021 starting at 10 am. There will be two ways for families to experience Connect2STEM 2021 - via the drive-through experience or Connect2STEM TV. Load up the car with your favorite nerds for a drive-through STEM experience. The entire family can enjoy fun activities while maintaining safe social distance.  See live performances, visit discovery zones and solve mysteries of science — and medicine throughout your drive. Due to space restrictions, limited tickets and time slots will be offered. Can't attend? Connect2STEM TV will be live throughout the day, showcasing some truly amazing STEM experiences for the whole family.</span></p> <p>For more information and to register go to: <a target="_blank" href="https://phoenixmed.arizona.edu/c2s">https://phoenixmed.arizona.edu/c2s</a> ​<br></p> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/111/Connect2STEM Image.jpg2020-11-04T07:00:00ZUA
Event: Biomedical Innovation Speaker Series Friday, November 6, 2020 11:00 am - 12:00 pm MST Lessons from The Long Fix: Biomedical Science and Engineering as Critical Levers in the Future of Health Care with Dr. Vivian LeeEvent: Biomedical Innovation Speaker Series Friday, November 6, 2020 11:00 am - 12:00 pm MST Lessons from The Long Fix: Biomedical Science and Engineering as Critical Levers in the Future of Health Care with Dr. Vivian Lee<div class="ExternalClass879F64768B1348CEBB9CC62E98691C03"><html> ​<strong style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;"><em>​Lessons from The Long Fix: Biomedical Science and Engineering as Critical Levers in the Future of Health Care with Dr. Vivian Lee</em></strong><br> <p>Vivian S. Lee, M.D., Ph.D., M.B.A., author of <em>The Long Fix: Solving America's Health Care Crisis with Strategies that Work for Everyone</em>, President of Health Platforms at Verily Life Sciences, physician and health care executive, and senior lecturer at Harvard Medical School will talk with ASU's Managing Director of Health and Clinical Partnerships, Susan M. Pepin, MD, MPH, about how technology has changed the future of medicine and healthcare delivery, from diagnosis and treatment to population health and the reduction of social disparities. Dr. Lee will also touch on how the field of biomedical science represents a rich landscape for innovation, entrepreneurship, and collaboration.<em> Sponsored by Arizona Biomedical Research </em></p> <p>Register here: <a href="https://urldefense.com/v3/__https:/asuevents.asu.edu/content/asu-biomedical-innovation-speaker-series__%3b%21%21LkjWUF49MRd51_ry%21N-9rLWzj0zWAKFacS7zFj_1wAGJnAF0dnLh2PwcgdG5vScdppO90lXW9cb_yIgg9eaYam1bCtdg$" target="_blank">https://asuevents.asu.edu/content/asu-biomedical-innovation-speaker-series [asuevents.asu.edu]</a>​<br></p> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>2020-10-30T07:00:00ZASU
Event: Biomedical Innovation Speaker Series Friday, November 13, 2020 11:00 am - 12:00 pm MST Bridging the Gap Between Data Science and Medicine with Dr. Melissa Haendel and Dr. Anthony Philippakis Event: Biomedical Innovation Speaker Series Friday, November 13, 2020 11:00 am - 12:00 pm MST Bridging the Gap Between Data Science and Medicine with Dr. Melissa Haendel and Dr. Anthony Philippakis <div class="ExternalClass2DA0FC84AEA94DFEAB6DC3B9B36FB289"><html> <p>​<span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">Vivian S. Lee, M.D., Ph.D., M.B.A., author of </span><em style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">The Long Fix: Solving America's Health Care Crisis with Strategies that Work for Everyone</em><span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">, President of Health Platforms at Verily Life Sciences, physician and health care executive, and senior lecturer at Harvard Medical School will talk with ASU's Managing Director of Health and Clinical Partnerships, Susan M. Pepin, MD, MPH, about how technology has changed the future of medicine and healthcare delivery, from diagnosis and treatment to population health and the reduction of social disparities. Dr. Lee will also touch on how the field of biomedical science represents a rich landscape for innovation, entrepreneurship, and collaboration.</span><em style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;"> Sponsored by Arizona Biomedical Research</em></p> <p>Register here: <a href="https://urldefense.com/v3/__https:/asuevents.asu.edu/content/asu-biomedical-innovation-speaker-series__%3b%21%21LkjWUF49MRd51_ry%21N-9rLWzj0zWAKFacS7zFj_1wAGJnAF0dnLh2PwcgdG5vScdppO90lXW9cb_yIgg9eaYam1bCtdg$" target="_blank">https://asuevents.asu.edu/content/asu-biomedical-innovation-speaker-series [asuevents.asu.edu]</a>​<br></p> <p> <br> </p> </html></div>2020-10-30T07:00:00ZASU
Event: Biomedical Innovation Speaker Series Friday, November 20, 2020 11:00 am - 12:00 pm MST Creating Innovation Ecosystems to Drive Knowledge-Led Inclusive Economic Development with Thomas Osha Event: Biomedical Innovation Speaker Series Friday, November 20, 2020 11:00 am - 12:00 pm MST Creating Innovation Ecosystems to Drive Knowledge-Led Inclusive Economic Development with Thomas Osha <div class="ExternalClass9D1638AB946B4C7687BA6671E3FB38F1"><html> <p>​<span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">T</span><span style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">homas Osha (Senior Vice President of Innovation and Economic Development at Wexford Science and Technology) will discuss how universities can leverage their research and technologies and collaborate across institutions and sectors to create knowledge-led economic development locally and globally. </span><em style="background-color:window;color:windowtext;font-family:inherit;font-size:10pt;">Sponsored by Arizona Biomedical Research</em></p> <p>Register here: <a href="https://urldefense.com/v3/__https:/asuevents.asu.edu/content/asu-biomedical-innovation-speaker-series__%3b%21%21LkjWUF49MRd51_ry%21N-9rLWzj0zWAKFacS7zFj_1wAGJnAF0dnLh2PwcgdG5vScdppO90lXW9cb_yIgg9eaYam1bCtdg$" target="_blank">https://asuevents.asu.edu/content/asu-biomedical-innovation-speaker-series [asuevents.asu.edu]</a><br></p> <p>​<br><br></p> </html></div>2020-10-30T07:00:00ZASU
PBC TODAYPBC TODAY<div class="ExternalClass7EC6D615A65B4814A4AF17CD3898932F"><html> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div>​<br></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-style:italic;font-weight:bold;">An update on the People, Places and Possibilities of the Phoenix Biomedical Campus in Downtown Phoenix • Oversight Provided by Arizona State University President Michael Crow, Northern Arizona University President Rita Cheng, University of Arizona President Robert Robbins, Arizona Board of Regents Executive Director John Arnold, and the City of Phoenix led by Mayor Kate Gallego</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">October 29, 2020</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="color:rgb(83, 102, 127);font-weight:bold;">Mark Your Calendars for the ASU Biomedical Innovation Speaker Series</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">Over the next four Fridays, join Arizona State University and the Arizona Biomedical Research Centre to hear top experts in the biomedical field. </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://na.eventscloud.com/ereg/index.php?eventid=581203&">Register here</a> <span style="font-size:12px;color:rgb(0, 0, 0);">.  </span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">How Biology will Build the Next Technology Revolution</span> </div> <div align="left"> <span style="font-size:12px;color:rgb(235, 169, 66);font-weight:bold;">Friday, Oct. 30, 2020, 11 a.m. to Noon</span> <span style="font-size:12px;color:rgb(0, 0, 0);font-weight:bold;"></span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">Susan Hockfield, Ph.D., world-renowned neuroscientist, president emerita at MIT and the author of "The Age of Living Machines: How Biology will Build the Next Technology Revolution," will discuss how discoveries at the convergence of biology and engineering can help us solve the greatest humanitarian, medical, and environmental issues of our time.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Lessons from the Long Fix: Biomedical Science and Engineering as Critical Levers in the Future of Health Care</span> </div> <div align="left"> <span style="font-size:12px;color:rgb(235, 169, 66);font-weight:bold;">Friday, Nov. 6, 2020, 11 a.m. to Noon</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">Vivian S. Lee, M.D., Ph.D., MBA, author of "The Long Fix: Solving America's Health Care Crisis with Strategies that Work for Everyone," president of Health Platforms at Verily Life Sciences, physician and health care executive and senior lecturer at Harvard Medical School, will talk with Susan M. Pepin, M.D., MPH, ASU's managing director of health and clinical partnerships, about how technology has changed the future of medicine and health care delivery, from diagnosis and treatment to population health and the reduction of social disparities. Dr. Lee will also touch on how the field of biomedical science represents a rich landscape for innovation, entrepreneurship and collaboration.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Bridging the Gap Between Data Science and Medicine</span> </div> <div align="left"> <span style="font-size:12px;color:rgb(235, 169, 66);font-weight:bold;">Friday, November 13, 2020, 11 a.m. to Noon</span> <span style="font-size:12px;color:rgb(0, 0, 0);font-weight:bold;"></span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">Join Anthony Philippakis, M.D., Ph.D., chief data scientist and institute scientist, the Broad Institute of MIT and Harvard, and Melissa Haendel, Ph.D., FACMI, director, director of the Center for Data to Health (CD2H) at Oregon Health & Science University and the Director of Translational Data Science at Oregon State University, will discuss how to leverage big data and collaborate across sectors and institutions in order to improve current understandings of population health, drive data-driven health research, improve patient outcomes, and reduce health disparities.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Creating Innovation Ecosystems to Drive Knowledge-Led Inclusive Economic Development</span> </div> <div align="left"> <span style="font-size:12px;color:rgb(235, 169, 66);font-weight:bold;">Friday, Nov. 20, 2020, 11 a.m. to Noon</span> <span style="font-size:12px;color:rgb(0, 0, 0);font-weight:bold;"></span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">Thomas Osha, senior vice president of innovation and economic development at Wexford Science and Technology, will discuss how universities can leverage their research and technologies and collaborate across institutions and sectors to create knowledge-led economic development locally and globally.</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PARTICULARS</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;font-family:"times new roman";font-size:medium;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="" width="100%" class=" editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text editor-text "> <div></div> <div class="text-container galileo-ap-content-editor"> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Contact:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <span style="font-size:12px;color:rgb(0, 0, 0);">David Krietor, Executive Director, 602-741-5580, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:david.krietor@asu.edu">david.krietor@asu.edu</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Website:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://urldefense.proofpoint.com/v2/url?u=https-3A__biomedicalphoenix.com_&d=DwMFaQ&c=l45AxH-kUV29SRQusp9vYR0n1GycN4_2jInuKy6zbqQ&r=ZkOduS1eiLUbvWLZ-8ug9vL9jHDR32Y_z26zPsk2vak&m=-wKoE3rm1i95DXGiQyqWJla6ia5YA9fsFMAO4vC9trM&s=XmoGrKj6ux3_Hjm5HLDxe1wzR5CGHEalThzpBkYVG90&e=">biomedicalphoenix.com</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:claudia.whitehead@phoenix.gov">Claudia Whitehead</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:claudia.whitehead@phoenix.gov">claudia.whitehead@phoenix.gov</a> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Events Calendar:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://asuevents.asu.edu/">ASU</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.pxu.org/Page/38">Bioscience H.S.</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://events.nau.edu/?view=grid&search=y">NAU</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://puhsaa.com/">PUHS Alumni Assoc.</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.tgen.org/giving/events/">TGen</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://uahs.arizona.edu/events">UArizona</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Jobs:</span> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://careers.insidehighered.com/jobs/?Keywords=%22phoenix+biomedical+campus%22#browsing">Inside Higher Ed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.indeed.com/jobs?q=%22phoenix%20Biomedical%20Campus%22&l=Phoenix%2c%20AZ&radius=0&vjk=9d8bff47682c0b93">Indeed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://jobs.azbio.org/">AZBio Job Center</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Getting Around:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://phoenixmed.arizona.edu/campus">Campus Map</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.valleymetro.org/maps-schedules">Public Transit</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="http://gridbikes.com/">Bike Share</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://parking.arizona.edu/parking/biomedical-campus/index.php?referral=compurchase">Parking</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;"> <a style="text-decoration-line:underline;color:rgb(83, 102, 127);" href="https://campaign.r20.constantcontact.com/render?ca=5ddc6f16-817d-48a0-a18c-b6c93f8a10fa&preview=true&m=1102821891921&id=preview" target="_blank">View as Webpage</a> </span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <p> <br> </p> </html></div>2020-10-29T07:00:00ZPhoenix Bio News
PBC TODAYPBC TODAY<div class="ExternalClass5EC5CAAFF60C4162AA7EA2B0761AC2FE"><html> ​ <span id="ms-rterangepaste-start"></span> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="" width="100%" class=" editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="line-height:1;font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;padding:10px 40px;" valign="top" align="left" class="editor-text editor-text "> <div class="text-container galileo-ap-content-editor"> <div> <span style="font-size:9px;color:rgb(0, 0, 0);">On October 19, 2020, the Tohono O'odham Nation committed $1 million to Arizona State University and the University of Arizona</span> </div> <div> <span style="font-size:9px;color:rgb(0, 0, 0);">to help researchers fight COVID-19. Attending the press conference at the Phoenix Biomedical Campus were, left to right, Regent Karrin Taylor Robson, Arizona Board of Regents, Nation Chairman Ned Norris Jr., Timothy Joaquin, the Nation's legislative chairman offering a blessing, UArizona President Robert Robbins, and ASU President Michael Crow. (Photo: Sun Belous/UArizona College of Medicine–Phoenix)</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="" width="100%" class=" editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"><tbody></tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:11px;color:rgb(83, 102, 127);font-style:italic;font-weight:bold;">An Update on the People, Places, and Possibilities of the Phoenix Biomedical Campus in Downtown Phoenix • Oversight provided by Arizona State University (Michael Crow, President), Northern Arizona University (Rita Cheng, President), University of Arizona (Robert Robbins, President), Arizona Board of Regents (John Arnold, Executive Director), and City of Phoenix led by Mayor Kate Gallego • October 28, 2020</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Expanding Our View</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">The perception of the Phoenix Biomedical Campus (PBC) is too narrow. The best example is Arizona State University (ASU). Judith Karshmer, Dean of the ASU Edson College of Nursing and Health Innovation, and Deborah Helitzer, Dean of the ASU College of Health Solutions, are not technically located on our 30-acre campus, but they can walk there in five minutes. Likewise, the students they teach and the researchers they collaborate with are all over the PBC. They populate the Arizona Biomedical Collaborative Building and Mercado, fronting both sides of East Van Buren Street, and will soon become an important presence in the Wexford/ASU Innovation building at 5th Street and Garfield.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">Given the thousands of students in these Downtown colleges and their natural connectivity to the PBC, we need to think bigger when we talk about the people, places, and possibilities – and our efforts to showcase their work and achievements. While we most often refer to the PBC as a center of biomedical research and education, we need to find room to include “health” in our PBC description. I welcome your suggestions and ideas. Give me a call at 602-741-5580 or </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:david.krietor@asu.edu?subject=Expanding%20our%20(PBC)%20View">send me an email</a> <span style="font-size:11px;color:rgb(0, 0, 0);">.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Volunteers Aid TGen’s Research</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">The researchers at the </span> <span style="font-size:11px;color:rgb(0, 0, 0);font-weight:bold;">Translational Genomics Research Institute</span> <span style="font-size:11px;color:rgb(0, 0, 0);"> (TGen) are pioneers in precision medicine and believe that every genome tells a story. Whether eye color, laughter, freckles or smile, our genes shape who we are in so many distinct and different ways. So, too, do they play more than a passing role in how we develop and react to disease, and as important, how we react to treatment. To understand complex diseases, TGen enrolls healthy and affected volunteers in TGen's research studies. This may be as simple as donating ten minutes to take a memory quiz or offering a saliva sample from a family pet. In other instances, participation may be restricted to those suffering from a particular genetic condition. The researchers at TGen invite you to participate in their current studies and forward them with those who may share your interest. </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.tgen.org/patients/participate-in-our-research/overview/">Click here to learn more and enroll</a> <span style="font-size:11px;color:rgb(0, 0, 0);">.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Take a (Virtual) Tour of TGen</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:11px;color:rgb(0, 0, 0);">Would you like to view the next generation sequencing technology and biomedical research laboratories where TGen scientists unlock the mysteries of cancer, diabetes, rare, and neurological disease? Unfortunately, in light of COVID-19, TGen employees are not able to bring guests into their building for a tour – but they can bring the tour to you… virtually. They have developed a digital walkthrough to provide a look inside their Phoenix Biomedical Campus headquarters, Center for Rare Childhood Disorders, TGen North in Flagstaff, and Pathogen and Microbiome Division. </span> <a style="text-decoration-line:underline;font-size:11px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.tgen.org/education/tour-tgen/">Click here to learn more and sign-up</a> <span style="font-size:11px;color:rgb(0, 0, 0);">.</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PEOPLE </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Noteworthy individuals making a difference</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.facebook.com/nau.occupational.therapy/posts/3598232496934946">NAU among recipients of 2020 ArizOTA Recognition Awards & Research Grants</a> (NAU, 10-26-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://news.yahoo.com/chances-getting-medical-school-145541368.html">What are your chances of getting into medical school?</a> (US News & World Report, 10-15-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PLACES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Properties and new developments where good things happen</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.cbre.us/research-and-reports/US-Life-Sciences-Report-2020">The bio-boom intensifies: Phoenix ranked #5 among U.S. top 10 emerging clusters</a> (CBRE, 10-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.bizjournals.com/phoenix/news/2020/10/11/downtown-phoenix-towers-capital-investment.html">Sky-defining projects, capital investment crafting denser downtown Phoenix</a> (Phoenix Business Journal, 10-11-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">POSSIBILITIES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Significant research & educational opportunities going on</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;text-align:left;font-size:12px;color:rgb(0, 0, 0);"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.wildcat.arizona.edu/article/2020/10/sc-cp-causes">New study challenges previous understanding about the causes of cerebral palsy</a> (UArizona, 10-20-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.medicalnewstoday.com/articles/poor-health-and-screen-time-on-different-devices-what-is-the-link">“Poor health” and screen time on different devices: What is the link?</a> (ASU, 10-10-20) </li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.eurekalert.org/pub_releases/2020-10/uoah-mnl100620.php">Many Non-Hodgkin's Lymphoma patients can skip radiation, collaborative study finds</a> (UArizona, 10-06-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;text-align:left;font-size:12px;color:rgb(0, 0, 0);"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="/news-events/92">TGen and Avery Therapeutics collaborate on development of engineered heart tissue</a> (TGen, 10-05-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://asunow.asu.edu/20201001-solutions-watching-your-waste">ASU researcher leads intervention to reduce household food waste</a> (ASU, 10-01-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="" width="100%" class=" editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);text-align:center;display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div style="text-align:left;" align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PANDEMIC RESPONSE</span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">PBC-affiliated experts weigh in on timely issue</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="" width="100%" class=" editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);text-align:center;display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.azfamily.com/news/continuing_coverage/coronavirus_coverage/phoenix-bar-prepares-to-begin-karaoke-again/article_4f292852-14e8-11eb-ad31-f7a3f02c5dae.html">Despite COVID-19, Phoenix bar prepares to begin karaoke again</a> (AZ Family, 10-22-20)</li> </ul> <div style="text-align:left;" align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;text-align:left;font-size:12px;color:rgb(0, 0, 0);"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://news.arizona.edu/story/tohono-oodham-nation-commits-1m-uarizona-combat-covid-19">Tohono O'odham Nation commits $1M to UArizona to combat COVID-19</a> (UArizona, 10-19-20)</li> </ul> <div style="text-align:left;" align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;text-align:left;font-size:12px;color:rgb(0, 0, 0);"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.azfamily.com/news/continuing_coverage/coronavirus_coverage/airlines-hope-safety-measures-can-lure-back-holiday-travelers/article_403d9348-0e7e-11eb-94c9-d75e0d3c1466.html">Airlines hope COVID-19 safety measures can lure back holiday travelers</a> (AZ Family, 10-14-20)</li> </ul> <div style="text-align:left;" align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://uahs.arizona.edu/news/uarizona-health-sciences-study-shows-sars-cov-2-antibodies-provide-lasting-immunity">UArizona Health Sciences study shows SARS-CoV-2 antibodies provide lasting immunit</a> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://uahs.arizona.edu/news/uarizona-health-sciences-study-shows-sars-cov-2-antibodies-provide-lasting-immunity">y</a> (UArizona, 10-12-20)</li> </ul> <div style="text-align:left;" align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a style="text-decoration-line:underline;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://ktar.com/story/3610328/uarizona-researchers-study-pain-relief-caused-by-coronavirus/">UArizona researchers study pain relief caused by COVID-19</a> (KTAR Radio, 10-07-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="text-align:center;" valign="top" align="left" width="100%" class="center-text content editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text center-text content-text"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PARTICULARS</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" class="galileo-ap-layout-editor" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td valign="top" align="" width="100%" class=" editor-col OneColumnMobile"> <div class="gl-contains-text"> <table style="border-collapse:collapse;table-layout:fixed;min-width:100%;" border="0" cellspacing="0" cellpadding="0" width="100%"> <tbody> <tr> <td style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;" valign="top" align="left" class="editor-text editor-text "> <div></div> <div class="text-container galileo-ap-content-editor"> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Contact:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <span style="font-size:12px;color:rgb(0, 0, 0);">David Krietor, Executive Director, 602-741-5580, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:david.krietor@asu.edu">david.krietor@asu.edu</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Website:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://urldefense.proofpoint.com/v2/url?u=https-3A__biomedicalphoenix.com_&d=DwMFaQ&c=l45AxH-kUV29SRQusp9vYR0n1GycN4_2jInuKy6zbqQ&r=ZkOduS1eiLUbvWLZ-8ug9vL9jHDR32Y_z26zPsk2vak&m=-wKoE3rm1i95DXGiQyqWJla6ia5YA9fsFMAO4vC9trM&s=XmoGrKj6ux3_Hjm5HLDxe1wzR5CGHEalThzpBkYVG90&e=">biomedicalphoenix.com</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:claudia.whitehead@phoenix.gov">Claudia Whitehead</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="mailto:claudia.whitehead@phoenix.gov">claudia.whitehead@phoenix.gov</a> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Events Calendar:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://asuevents.asu.edu/">ASU</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.pxu.org/Page/38">Bioscience H.S.</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://events.nau.edu/?view=grid&search=y">NAU</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://puhsaa.com/">PUHS Alumni Assoc.</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.tgen.org/giving/events/">TGen</a> <span style="font-size:12px;color:black;">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://uahs.arizona.edu/events">UArizona</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Jobs:</span> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://careers.insidehighered.com/jobs/?Keywords=%22phoenix+biomedical+campus%22#browsing">Inside Higher Ed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.indeed.com/jobs?q=%22phoenix%20Biomedical%20Campus%22&l=Phoenix%2c%20AZ&radius=0&vjk=9d8bff47682c0b93">Indeed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://jobs.azbio.org/">AZBio Job Center</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Getting Around:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://phoenixmed.arizona.edu/campus">Campus Map</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://www.valleymetro.org/maps-schedules">Public Transit</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="http://gridbikes.com/">Bike Share</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);" target="_blank" rel="noopener noreferrer" href="https://parking.arizona.edu/parking/biomedical-campus/index.php?referral=compurchase">Parking</a> </div> <div> <br>​<br></div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/113/Donation Press Conference-4657.jpg2020-10-28T07:00:00ZPhoenix Bio News
TGEN APPOINTS DR. SUNIL SHARMA PHYSICIAN-IN-CHIEFTGEN APPOINTS DR. SUNIL SHARMA PHYSICIAN-IN-CHIEF<div class="ExternalClassF2D403924E694DFA81AF730AD7C72B76"><html> <div class="row" style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;"> <div class="col-md-12" style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;"> <ul class="list-inline posted-info" style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;"> <li style="box-sizing:border-box;border-radius:0px;color:rgb(85, 85, 85);display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;"> <div style="box-sizing:border-box;border-radius:0px;"> <span style="box-sizing:border-box;border-radius:0px;">Written by</span> <span class="uBlogsy_author_name" style="box-sizing:border-box;border-radius:0px;"><a target="_blank" href="https://www.tgen.org/news/?author=Steve+Yozwiak" title="Steve Yozwiak" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;">Steve Yozwiak</a></span></div> </li> </ul> <ul class="list-inline posted-info" style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;"> <li style="box-sizing:border-box;border-radius:0px;color:rgb(85, 85, 85);display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;">Posted Tuesday October 27, 2020<br><br></li> </ul> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <em style="box-sizing:border-box;border-radius:0px;">New title reflects growing role and responsibility in helping guide TGen research across multiple scientific disciplines</em> </p> </div> </div> <div class="row" style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;"> <div class="col-md-12" style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">PHOENIX, Ariz. — Oct. 27, 2020</span> — The <a target="_blank" href="https://www.tgen.org/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a target="_blank" href="https://www.cityofhope.org/homepage" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">City of Hope</a>, today announced the appointment of <a target="_blank" href="https://www.tgen.org/faculty-profiles/sunil-sharma/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Sunil Sharma</a>, M.D., F.A.C.P., M.B.A., as Physician-in-Chief. Dr. Sharma succeeds <a target="_blank" href="https://www.tgen.org/faculty-profiles/daniel-von-hoff/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Daniel D. Von Hoff</a>, M.D., F.A.C.P., a leading expert in pancreatic cancer, who was instrumental in developing key clinical and research programs at TGen.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Dr. Von Hoff, who joined TGen in 2003, will continue as a Distinguished Professor and Executive Vice President, Molecular Medicine, to further his work in pancreatic cancer research and clinical trials.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">“Dr. Von Hoff's commitment to TGen and patients with pancreas cancer is second to none,” said <a target="_blank" href="https://www.tgen.org/faculty-profiles/jeffrey-trent/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Dr. Jeffrey Trent</a>, TGen President and Research Director. “This transition provides him the opportunity to focus his energies solely on pancreas cancer research and treatment, a disease against which he’s made profound advances.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Dr. Trent added: “Dr. Sharma’s appointment as Physician-in-Chief recognizes the important role he has played across TGen’s many biomedical disciplines since his arrival. He is a distinguished researcher and clinician. In addition to his leadership at TGen, he is rapidly bringing research in clinical efforts in immune treatments to the forefront of patient benefit.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <a target="_blank" href="https://www.tgen.org/news/2017/september/29/dr-sunil-sharma-joins-tgen/?search=Sunil" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Dr. Sharma joined TGen</a> in 2017 as Deputy Director of Clinical Sciences, Professor, and Head of TGen’s Applied Cancer Research and Drug Discovery Division, but Dr. Von Hoff knew him years before that.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">“It has been a privilege to know and work with Dr. Sharma over many decades, and I look forward to his leadership in the years ahead," said Dr. Von Hoff. "His intellect, drive, insights and innovative approaches will serve TGen — but more importantly patients — well. With this outstanding physician scientist, there is no doubt the office of Physician-in-Chief is in incredibly capable hands."</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Dr. Sharma is also a Professor of Medical Oncology at City of Hope, a world-renowned comprehensive cancer center that also treats diabetes and other life-threatening diseases, and co-leader of City of Hope’s Developmental Cancer Therapeutics Program.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <a target="_blank" href="https://www.cityofhope.org/faculty/steven-rosen" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Steven Rosen</a>, M.D., Provost and Chief Scientific Officer at City of Hope, said: “Over the past three years, Dr. Sunil Sharma has proven to be a catalyst for innovative research and has successfully collaborated with others to combine research resources at TGen and City of Hope. We have every confidence that in his new role, Dr. Sharma will assist in further strengthening the leading-edge research ties between City of Hope and TGen.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Dr. Sharma’s nearly three-decade career spans the areas of research, drug and clinical trial development. At TGen, he broadened his research and clinical portfolio beyond his specialty of gastrointestinal cancers (colon, pancreatic) to include drug development — immunotherapeutic treatments in particular — for COVID-19, Alzheimer’s disease, memory performance, and other cancers, including breast and ovarian cancer.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">"I am grateful for the opportunity this new role provides, and humbled to follow in the footsteps of Dr. Von Hoff,” said Dr. Sharma. “I look forward to collaborating more broadly across the institute in search of new opportunities for patient benefit, and am committed to keeping TGen at the forefront of precision medicine.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Prior to TGen, Dr. Sharma served as Deputy Director of Huntsman Cancer Institute (HCI) in Salt Lake City, a National Cancer Institute-designated Comprehensive Cancer Center. At Huntsman, he co-led the Experimental Therapeutics Program, where he developed new therapeutics, including image-guided and targeted drug delivery systems. He also worked as a physician in the Division of Gastrointestinal Oncology at Memorial Sloan Kettering Cancer Center in New York, and he built a phase I clinical trial program at the Nevada Cancer Institute in Las Vegas.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Nicholas J. Vogelzang, M.D., a medical oncologist with the Comprehensive Cancer Centers of Nevada, said: “Dr. Sharma has been at the forefront of anti-cancer drug development for over two decades. Having trained with Dr. Von Hoff, he expanded his innovative work at Novartis, the Nevada Cancer Institute, the Huntsman and now as Physician-in-Chief at TGen. He is a kind, yet driven, leader in the mold of Drs. Von Hoff and Trent. He understands the complex pathways that drive cancer and the immune response to it. We, in the cancer research world, are fortunate to have Dr. Sharma now leading TGen to even greater breakthroughs.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">In addition to his clinical efforts, Dr. Sharma has worked with a number of pharmaceutical companies, including Swiss-based Novartis, where he helped develop ceritinib, one of the most widely used anti-lung cancer agents; Merck & Co.’s pembrolizumab; and Bristol-Myers Squibb’s nivolumab, the latter two immunotherapy drugs, both of which help the body’s own immune system attack cancer cells.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">John Sweetenham, M.D., a Professor of Medicine and Associate Director of Clinical Affairs at the University of Texas Southwestern Harold C. Simmons Comprehensive Cancer Center, said: “A distinguished physician-scientist and clinical investigator, Dr. Sharma is also a highly skilled and compassionate physician and an exceptional leader. His success in guiding drug development from discovery science to meaningful patient impact speaks for itself. Congratulations to Dr. Sharma for this recognition of his exceptional contribution, and congratulations to TGen for appointing a truly outstanding Physician-in-Chief.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Dr. Sharma, a Fellow of the American College of Physicians, earned his medical degree at the University of Delhi in New Delhi, India, and his M.B.A. from the University of Massachusetts, Amherst.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);text-align:center;"># # #</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">About TGen, an affiliate of City of Hop</span> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">e<br style="box-sizing:border-box;border-radius:0px;"></span>Translational Genomics Research Institute (TGen) is a Phoenix, Arizona-based non-profit organization dedicated to conducting groundbreaking research with life-changing results. TGen is affiliated with City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases: <a target="_blank" href="https://www.cityofhope.org/homepage" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">www.cityofhope.org</a>.  This precision medicine affiliation enables both institutes to complement each other in research and patient care, with City of Hope providing a significant clinical setting to advance scientific discoveries made by TGen. TGen is focused on helping patients with neurological disorders, cancer, diabetes and infectious diseases through cutting-edge translational research (the process of rapidly moving research toward patient benefit).  TGen physicians and scientists work to unravel the genetic components of both common and complex rare diseases in adults and children.  Working with collaborators in the scientific and medical communities worldwide, TGen makes a substantial contribution to help our patients through efficiency and effectiveness of the translational process. For more information, visit: <a target="_blank" href="https://www.tgen.org/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">www.tgen.org</a>. Follow TGen on <a target="_blank" href="https://www.facebook.com/helptgen" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Facebook</a>, <a target="_blank" href="https://www.linkedin.com/company/tgen/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">LinkedIn</a> and <a target="_blank" href="https://twitter.com/TGen" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Twitter @TGen</a>.<br style="box-sizing:border-box;border-radius:0px;"><br style="box-sizing:border-box;border-radius:0px;"><span style="box-sizing:border-box;border-radius:0px;font-weight:700;">Media Contact:<br style="box-sizing:border-box;border-radius:0px;"></span>Steve Yozwiak<br style="box-sizing:border-box;border-radius:0px;">TGen Senior Science Writer<br style="box-sizing:border-box;border-radius:0px;">602-343-8704<br style="box-sizing:border-box;border-radius:0px;"><a target="_blank" href="mailto:syozwiak@tgen.org" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">syozwiak@tgen.org</a> </p> <aside class="uBlogsy_post_details" style="box-sizing:border-box;border-radius:0px;"> <div class="uBlogsy_tag_container" style="box-sizing:border-box;border-radius:0px;overflow:hidden;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"> <ul class="margin-left-5 list-inline tags-v2 uBlogsy_font_style50" style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:5px;list-style:none;font-size:11px;"></ul> </div> <div class="uBlogsy_label_container" style="box-sizing:border-box;border-radius:0px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"> <div class="uBlogsy_labels_container" style="box-sizing:border-box;border-radius:0px;"></div> </div> </aside> <br> </div> </div> <p> <br> </p> </html></div>2020-10-27T07:00:00ZTGen
Asking Algorithms and Ourselves the Right QuestionsAsking Algorithms and Ourselves the Right Questions<div class="ExternalClass98E9DAE9DAFE4AF98404EB45B1871B94"><html> <p>​<span style="color:rgb(155, 155, 155);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;text-transform:uppercase;background-color:window;box-sizing:border-box;" class="field field--name-title field--type-string field--label-hidden">TERESA JOSEPH</span><span style="color:rgb(155, 155, 155);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;text-transform:uppercase;background-color:window;"></span></p><div><div class="field field--name-field-news-media-contact-ref field--type-entity-reference field--label-hidden field__item" style="box-sizing:border-box;color:rgb(96, 96, 96);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:16px;"><article role="article" class="node node--type-media-contact node--promoted node--view-mode-default" style="box-sizing:border-box;"><div class="d-flex flex-nowrap align-items-center mb-4" style="box-sizing:border-box;display:flex !important;flex-wrap:nowrap !important;align-items:center !important;margin-bottom:1.5rem !important;"> <a class="field_media_contact_twitter_url" target="_blank" href="https://twitter.com/uazmedphx/" style="box-sizing:border-box;background-color:transparent;color:rgb(1, 28, 72);"> <em></em> </a> </div> </article> </div> <div class="field field--name-field-subtitle field--type-string field--label-hidden h5 mb-lg-3 text-dark field__item" style="box-sizing:border-box;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;font-size:1.25rem;color:rgb(33, 33, 33) !important;">Dr. Ziad Obermeyer Discussed the Opportunities and Challenges of Algorithms in Health Care at Buffmire Lecture</div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item" style="box-sizing:border-box;color:rgb(96, 96, 96);font-size:15px;line-height:20px;margin-bottom:3rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";"> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Algorithms might be the answer to some of health care’s most challenging questions — from measuring health care management to understanding health disparities and bias. <a target="_blank" href="https://publichealth.berkeley.edu/people/ziad-obermeyer/" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;">Ziad Obermeyer, MD</a>, an associate professor of Health Policy and Management at UC Berkeley School of Public Health, discussed how these algorithms can benefit the health care system, but can also stumble when asking tough questions.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p> <figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:250px;height:auto;background-color:rgb(232, 237, 243) !important;"> <div class="figure-img" style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;"> <img alt="Ziad Obermeyer, MD" class="img-fluid" data-entity-type="file" data-entity-uuid="a6b438b1-4500-4c4d-ab14-a25808ead63a" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/buffmire-story.jpg" title="Ziad Obermeyer, MD" style="box-sizing:border-box;border-width:0px;vertical-align:middle;max-width:100%;margin:5px;width:0px;" /> </div> <figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;font-size:14px;line-height:20px;margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;"> <em style="box-sizing:border-box;">Ziad Obermeyer, MD</em> </figcaption> </figure>On Oct. 22, <a target="_blank" href="https://youtu.be/WUlPfDgwKzo" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;">Dr. Obermeyer presented at the Flinn Foundation Buffmire Lecture Series</a>, which introduces renowned medical educators and practitioners to Arizona. The University of Arizona College of Medicine <span lang="EN" style="box-sizing:border-box;">–</span> Phoenix and Flinn Foundation event took place via Zoom.<p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Dr. Obermeyer started his presentation by discussing specific, measurable, attainable, relevant and time-based (SMART) setting goals. He provided a few examples of ways to set these realistic and measurable goals, including the goal of having a good life. In order to measure the goal of having a good life, you need to define a proxy. </p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Dr. Obermeyer said that these proxies remind him of a genre of joke called the literal genie joke. These are jokes that start like, “I want to be rich,” and the genie says, “okay, Rich. What is your second wish?”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“We need to be careful what we wish for in life with proxy measures and algorithms, because algorithms are the genie that you can ask anything you want, but you have to be really careful,” he said.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Dr. Obermeyer’s work is related to population health management. The idea of improving clinical health outcomes of a defined group of individuals by being proactive and intervening before patients get sick. An example of this is highly trained nurses who are on call when patients have a problem. If that phone call leads the nurse to worry that a patient needs help, that nurse can arrange for a same day primary care visit, do at-home visits, rearrange medication and refill prescriptions.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“The problem is, all of that stuff is expensive,” Dr. Obermeyer said. “We cannot do this for everyone; we just don’t have the resources to do it. We need to target those things for the people who really need it. That is where algorithms come in.”</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Algorithms make decisions about population health management interventions for the majority of the U.S. population, according to Dr. Obermeyer. They predict the patients who will get sick, need hospitalization, rehabilitation and patients who will consume a lot of health care resources. However, these algorithms sometimes stumble.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Dr. Obermeyer provided an example of an algorithm that was designed to predict who will be using a lot of health care resources within the next year. Imagine there are two patients and the algorithm predicts both these patients will have a high-risk score of 97.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“It stands to reason that these two patients should go on to have the same needs for that health care and population health management, regardless of the color of their skin,” Dr. Obermeyer said.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">However, that is not the case. Researchers found that the first patient, who was white, had mild depression, took citalopram, had a knee replacement earlier in the year and is now healthy. The second patient, who was black, had diabetes, heart failure and COPD. He was on insulin and seven other medications. Over the course of this year, where they predicted his utilization, he had two ER visits, two hospitalizations, one ending up in a prolonged rehab stay.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“In general, when we looked at patients who had the same algorithm score, patients of color had more active chronic illness; they had biomarkers consistent with worse health, like higher blood pressure, worse kidney function, worse anemia, etc. It doesn’t matter how you measure this health. What we saw was black patients with the same score who were on average far less healthy,” Dr. Obermeyer said.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">According to that algorithm, only 18 percent of the high-risk group was black. In an unbiased world, that number should have been about 47 percent. When researching the issue, Dr. Obermeyer’s team discovered that it was the question the algorithm was answering — which was high health care costs, rather than health care needs. When they refocused the question on health care needs, the algorithm reduced its bias by 84 percent.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">This discovery led to Dr. Obermeyer’s team developing an initiative to help organizations fix algorithm bias and build up data sets to allow the opportunity for more algorithms to be created and adjusted.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">“We worry a lot about algorithmic bias, and I think a lot of that work is well founded, but I think there is great cause for optimism,” Dr. Obermeyer said. “Just as algorithms can be biased, they can also be unbiased. Just as they can replicate existing problems with scientific knowledge, they can discover new knowledge by listening to patients. It is going to be up to what data we have available to build algorithms, what seemingly small technical choices we make when we train them. I think that is why this area is so exciting for me, because small things like making data sets available, making the right choice when you are training an algorithm, can make a huge difference.”</p><ul style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><li style="box-sizing:border-box;"><a target="_blank" href="https://youtu.be/WUlPfDgwKzo" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;">Watch the full lecture</a>.​<br></li></ul></div> </div> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>2020-10-27T07:00:00ZUA
ONCOMYX ANNOUNCES PRESENTATION OF PRECLINICAL DATA FOR NOVEL ONCOLYTIC VIROTHERAPY AT AACR TUMOR IMMUNOLOGY AND IMMUNOTHERAPY VIRTUAL CONFERENCEONCOMYX ANNOUNCES PRESENTATION OF PRECLINICAL DATA FOR NOVEL ONCOLYTIC VIROTHERAPY AT AACR TUMOR IMMUNOLOGY AND IMMUNOTHERAPY VIRTUAL CONFERENCE<div class="ExternalClassF2027DDBE947470991B7F23CFEEE2B79"><html> <p>​<a target="_blank" href="https://oncomyx.wpengine.com/" style="font-family:raleway, sans-serif;font-size:18px;background-color:transparent;box-sizing:inherit;text-decoration-line:underline;color:rgb(78, 162, 196);transition:color 110ms ease-in-out 0s;">OncoMyx Therapeutics</a><span style="color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;background-color:window;">, a privately-held viral immunotherapy company, announced the presentation of preclinical data at the</span><span style="color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;background-color:window;"> </span><a target="_blank" href="https://www.aacr.org/meeting/tumor-immunology-and-immunotherapy-2020/" style="font-family:raleway, sans-serif;font-size:18px;background-color:transparent;box-sizing:inherit;text-decoration-line:underline;color:rgb(78, 162, 196);transition:color 110ms ease-in-out 0s;">AACR Virtual Special Conference</a><a target="_blank" href="https://www.aacr.org/meeting/tumor-immunology-and-immunotherapy-2020/" style="font-family:raleway, sans-serif;font-size:18px;background-color:transparent;box-sizing:inherit;text-decoration-line:underline;color:rgb(78, 162, 196);transition:color 110ms ease-in-out 0s;margin-bottom:0px;">: Tumor Immunology and Immunotherapy</a><span style="color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;background-color:window;"> </span><span style="color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;background-color:window;">taking place October 19 to 20. The data are the first to demonstrate preclinical therapeutic activity alone and in combination with immune checkpoint inhibitors of the company’s armed myxoma virotherapy in development to improve cancer treatment.</span></p> <p style="box-sizing:inherit;margin:32px 0px;max-width:100%;color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;">The talk entitled, “Armed Myxoma Virus Demonstrates Therapeutic Activity Alone and in Combination with Immune Checkpoint Inhibitors in Preclinical Xenograft Models,” will be presented virtually by OncoMyx’s Chief Scientific Officer, Leslie L. Sharp, Ph.D., on October 20 at 11:55-12:25 ET.</p> <p style="box-sizing:inherit;margin:32px 0px;max-width:100%;color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;">“The myoxma virus is highly immuno-interactive and can selectively infect and kill a broad range of cancer cell types,” said Dr. Sharp. “Myxoma’s large genome is ideal for multi-arming to create a unique precision medicine approach to oncolytic viruses. We are also especially encouraged by this data that is the first to demonstrate efficacy of our myxoma virotherapy in a number of tumor models across multiple disease indications, suggesting we could pursue a pan-tumor approach. The further synergy of our myxoma virotherapy with immune checkpoint inhibitors could expand the therapeutic effectiveness of immunotherapies.”</p> <p style="box-sizing:inherit;margin:32px 0px;max-width:100%;color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;">Myxoma is a large dsDNA pox virus suitable for intratumoral or intravenous oncolytic virotherapy and is engineerable to carry multiple transgenic payloads with robust transgene production and function. The data further show that OncoMyx’s myxoma virotherapy is efficacious in multiple <em style="box-sizing:inherit;margin-top:0px;">in vitro </em>and <em style="box-sizing:inherit;margin-bottom:0px;">in vivo </em>tumor models, including subcutaneous and metastatic syngeneic tumor models, and provides combinatorial efficacy with immune checkpoint inhibitors.</p> <p style="box-sizing:inherit;margin:32px 0px;max-width:100%;color:rgb(97, 98, 101);font-family:raleway, sans-serif;font-size:18px;"> <span style="box-sizing:inherit;font-weight:bolder;margin-top:0px;margin-bottom:0px;">About OncoMyx Therapeutics</span> OncoMyx Therapeutics develops viral immunotherapies based on the myxoma virus (MYXV) platform to orchestrate an immune response to better treat cancer. Successful immuno-oncology (IO) cancer treatment generally requires combination therapy, and oncolytic viruses (OVs) have emerged as a safe and effective IO complement. The company’s MYXV platform, exclusively licensed from Arizona State University, is poised to be a best-in-class OV approach, and the top OV team has assembled around MYXV to create important new therapeutic options for cancer patients.​<br></p> <p> <br> </p> </html></div>2020-10-19T07:00:00ZOncoMyx Therapeutics
Participate in our ResearchParticipate in our Research<div class="ExternalClass3324F7F65CD7463C893B4EBDF7FEF36C"><html> <p>​<span style="color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;">At TGen, we are pioneers in precision medicine and believe that every genome tells a story. Whether eye color, laughter, freckles or smile, our genes shape who we are in so many distinct and different ways. So, too, do they play more than a passing role in how we develop and react to disease, and as important, how we react to treatment. </span></p><p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 10px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"><br style="box-sizing:border-box;border-radius:0px;">To understand complex diseases, we enroll healthy and affected volunteers in TGen's research studies. This may be as simple as donating ten minutes of your time to take a memory quiz or offering a saliva sample from a family pet. In other instances, participation may be restricted to those suffering from a particular genetic condition. We invite you to participate in our current studies and forward them with those who may share your interest. Thank you in advance for helping advance our research.<br></p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 10px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"> <a target="_blank" href="https://www.tgen.org/patients/participate-in-our-research/overview/">C<span style="background-color:window;">URRENT STUDIES​</span></a> </p> </html></div>2020-10-07T07:00:00ZTGen
Event: The Foundation, Development, and Evolution of a Self-Management Support System TUESDAY, OCTOBER 13, 2020 2:00 PM TO 2:45 PMEvent: The Foundation, Development, and Evolution of a Self-Management Support System TUESDAY, OCTOBER 13, 2020 2:00 PM TO 2:45 PM<div class="ExternalClassB58A0D76759948A48BF6A4CB3C889FD2"><html> <p>​<span style="color:rgb(0, 114, 198);font-family:"Segoe UI Semilight", "Segoe UI", Segoe, Tahoma, Helvetica, Arial, sans-serif;font-size:1.46em;background-color:window;">Event: </span><a target="_blank" href="https://phoenixmed.arizona.edu/about/events/tech-talk-tuesdays" style="font-family:"Segoe UI Semilight", "Segoe UI", Segoe, Tahoma, Helvetica, Arial, sans-serif;font-size:1.46em;background-color:window;"><strong>The Foundation, Development, and Evolution of a Self-Management Support System</strong></a><strong style="color:rgb(0, 114, 198);font-family:"Segoe UI Semilight", "Segoe UI", Segoe, Tahoma, Helvetica, Arial, sans-serif;font-size:1.46em;background-color:window;"> </strong><span style="color:rgb(0, 114, 198);font-family:"Segoe UI Semilight", "Segoe UI", Segoe, Tahoma, Helvetica, Arial, sans-serif;font-size:1.46em;background-color:window;">TUESDAY, OCTOBER 13, 2020 2:00 PM TO 2:45 PM</span><span style="color:rgb(0, 114, 198);font-family:"Segoe UI Semilight", "Segoe UI", Segoe, Tahoma, Helvetica, Arial, sans-serif;font-size:1.46em;background-color:window;">​</span></p><span id="ms-rterangepaste-start"></span><h2 style="box-sizing:border-box;margin-top:0px;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;color:rgb(30, 82, 136);">The Foundation, Development, and Evolution of a Self-Management Support System</h2><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;color:rgb(96, 96, 96);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;">Technology can play a critical role in guiding self-management for older adults. Learn how research findings have led to the development of technologies such as smartphone apps to improve medication adherence and other beneficial  behavioral interventions for an aging population.</p><h3 style="box-sizing:border-box;margin-top:0px;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;color:rgb(30, 82, 136);">Presenter</h3><ul style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;color:rgb(96, 96, 96);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;"><li style="box-sizing:border-box;">Kathie Insel, PhD, RN, professor and chair, Biobehavioral Health Sciences Division, UArizona College of Nursing</li></ul><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;color:rgb(96, 96, 96);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;">Upon <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="https://arizona.zoom.us/meeting/register/tJMlceqvqDkrGdNu1_tcheLeCVY0KAUXytIC" target="_blank">completion of registration</a>, Zoom details will be included in a confirmation email.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;color:rgb(96, 96, 96);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:15px;"><span style="box-sizing:border-box;font-weight:bolder;">For inquiries about access</span> or to request any disability-related accommodations that will facilitate your full participation, please contact the Health Sciences Engagement Office at <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="mailto:uahsevents@email.arizona.edu" target="_blank">uahsevents@email.arizona.edu</a> | 520-621-4436.<br style="box-sizing:border-box;"><br style="box-sizing:border-box;"><span style="box-sizing:border-box;font-weight:bolder;">For more information</span>, contact: Kaitlyn Armendariz Shergill, Manager, Outreach and Engagement at <a style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration-line:underline;transition:all 0.3s ease 0s;" href="mailto:karmendariz@email.arizona.edu" target="_blank">karmendariz@email.arizona.edu</a> | 520-621-4436.​<br></p><span id="ms-rterangepaste-end"></span><p><span style="color:rgb(0, 114, 198);font-family:"Segoe UI Semilight", "Segoe UI", Segoe, Tahoma, Helvetica, Arial, sans-serif;font-size:1.46em;background-color:window;"><br></span></p> <p> <br> </p> </html></div>2020-10-07T07:00:00ZUA
TGEN, AVERY THERAPEUTICS COLLABORATION STUDIES MECHANISM OF ACTION IN ENGINEERED HEART TISSUETGEN, AVERY THERAPEUTICS COLLABORATION STUDIES MECHANISM OF ACTION IN ENGINEERED HEART TISSUE<div class="ExternalClassC69398967DEC40DC98615DD68D732637"><html> <p>​<span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;box-sizing:border-box;border-radius:0px;">Written by</span><span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;"> </span><span style="font-style:italic;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;background-color:window;box-sizing:border-box;border-radius:0px;" class="uBlogsy_author_name"><a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;" title="Steve Yozwiak" href="https://www.tgen.org/news/?author=Steve+Yozwiak" target="_blank">Steve Yozwiak</a>​</span></p> <ul style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="list-inline posted-info"> </ul> <span id="ms-rterangepaste-start"></span> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <em style="box-sizing:border-box;border-radius:0px;">TGen’s analysis of proteins and metabolites could pave the way for Avery Therapeutics to gain FDA approval of human clinical trials</em> </p> </div> </div> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">PHOENIX and TUCSON, Ariz. — Oct. 5, 2020 —</span> <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://averythera.com/" target="_blank">Avery Therapeutics Inc.</a> of Tucson has  developed an engineered heart tissue, a lab-grown cardiac membrane that can help heal the heart, either following a heart attack or as a result of progressive heart disease.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">The heart tissue, called MyCardia™, could revolutionize the treatment of cardiovascular disease, and someday might be applied to other failing organs.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">To better understand how MyCardia works — at the infinitesimally small molecular level — Avery has partnered with the <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/" target="_blank">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.cityofhope.org/homepage" target="_blank">City of Hope</a>, following an introduction made by the <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://flinn.org/bioscience/arizonas-bioscience-roadmap/entrepreneurship-program/" target="_blank">Flinn Foundation</a>.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Avery turned to TGen to understand which of their membranes are releasing molecules that produce therapeutic benefits,” said <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/faculty-profiles/patrick-pirrotte/" target="_blank">Dr. Patrick Pirrotte</a>, Assistant Professor and Director of TGen’s Collaborative Center for Translational Mass Spectrometry. “Our collaboration will help them understand the mechanism of action on the molecular level, and the potential benefits to patients.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">TGen is conducting mass spectrometry analysis of the proteins and metabolites at work in MyCardia’s healing effect on heart-muscle tissue. This supporting data will be used in Avery’s submissions to the Food and Drug Administration (FDA) that could lead to human clinical trials. Up to now, Avery has studied the processes in laboratory and preclinical experiments.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Avery’s technology is amazing,” Dr. Pirrotte said, noting that the MyCardia membranes actually beat like a heart. “Their idea is that, for a heart that is potentially weak, an inserted cardiac membrane could support regeneration of heart tissue.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Avery licensed the technology for MyCardia from the University of Arizona, where Avery scientists had worked on developing engineered regenerative tissues to treat cardiovascular disease.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Key to the technology is the advancement in recent years of induced pluripotent stem cells (iPSCs), which can propagate indefinitely and theoretically give rise to every other cell type in the body. They represent a source of cells that could be used to replace those lost to damage or disease. Advancements in iPSC technology led to a Nobel Prize in 2012.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“It’s the concept of being able to take essentially any cell in the body and convert it into an embryonic-like cell, and then being able to make any cell. That’s how we are making our heart-muscle cells,” said Dr. Jordan Lancaster, Avery’s Chief Executive Officer.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Dr. Jen Koevary, Avery’s Chief Operating and Financial Officer, added: “We created the material based on the idea that you can use healthy cells to treat an unhealthy tissue and make it healthy again.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">The Nation’s leading cause of death</span> </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">More than 30 million Americans have heart disease, resulting in over $39 billion annually in medical treatment costs. Nearly 600,000 patients are newly diagnosed each year, and <span style="box-sizing:border-box;border-radius:0px;">650,000 Americans die annually, making it the nation’s leading cause of death.</span></p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">The condition is most often treated with drugs, but those efforts eventually fail. Heart transplants can help, but suitable donors are scarce, enabling fewer than 3,000 transplants each year. Mechanical hearts that run on battery packs also can help, but they are expensive; patients are often left with limited mobility, poor quality of life and frequent hospital visits.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">How MyCardia works</span> </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;">Through</span> minimally invasive laparoscopic or robotic surgery, MyCardia is precisely grafted onto the surface of a damaged heart. It is loaded with a therapeutic cellular payload; a proprietary combination of cardiomyocytes (heart-muscle cells) and fibroblasts (general cells of the body).</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Over time, the MyCardia membrane secretes proteins and metabolites, collectively called the secretome, which helps enable the heart to heal itself. The MyCardia eventually disappears. It’s the unique secretome that is being studied at TGen.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“We have lots of data, but we really don’t know what makes it tick,” Dr. Lancaster said.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">There are hundreds of factors involved in the MyCardia process, explained Dr. Koevary: “Figuring out exactly how it works is very complex. It’s important for us to know how it’s working so we can, in the future, identify the best patients who would be candidates for treatment.”​<br></p> </div> </div> <span id="ms-rterangepaste-end"></span> <br> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/92/patrick-pirrotte.png2020-10-05T07:00:00ZTGen
Phoenix Union Bioscience High School was recently notified that Principal Dr. Holly Batsell has earned the 2020 Maricopa County Exemplary Principal Award.Phoenix Union Bioscience High School was recently notified that Principal Dr. Holly Batsell has earned the 2020 Maricopa County Exemplary Principal Award.<div class="ExternalClass6DC17C32A0AD45378B512E7090824B99"><html> <p>​</p> <span id="ms-rterangepaste-start"></span> <p style="font-family:montserrat, arial, sans-serif;font-size:19px;">The Maricopa County Exemplary Principal Award, formerly known as the Rodel Exemplary Principal Award, recognizes principals in Maricopa County who exemplify practices and leadership that contribute to high expectations and exceptional student learning. Principals are chosen based on a robust nomination process that includes five phases. Aspects of the process involve a site visit, interviews with staff members, classroom walkthroughs, and an observation of a leadership team meeting.</p> <p style="font-family:montserrat, arial, sans-serif;font-size:19px;">The process includes a review of the last three years of achievement data to identify schools with a history of high student achievement, student growth, and teacher retention. Superintendents are then invited to nominate principals who meet the established criteria.</p> <p style="font-family:montserrat, arial, sans-serif;font-size:19px;">“Bioscience High School, with Dr. Holly Batsell’s steady leadership for the past four years, is routinely ranked as one of the top high schools in Arizona, earning an “A” for the past two years”, said PXU Superintendent Dr. Chad Gestson. “With an emphasis on an integrated, rigorous curriculum while incorporating science, technology, engineering, and math, Dr. Batsell has successfully focused on increasing ACT scores and increasing student enrollment and retention. She has high expectations for herself and her staff.” Dr. Gestson continued, “these expectations have translated into positive and supportive school culture. This, in turn, consistently promotes student success. Bioscience students receive hundreds of thousands of dollars in scholarships each year and many go on to successful STEM careers. The honor of being named a National Blue Ribbon School is a reflection of the hard work and dedication of all Bioscience staff.”​<br></p> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/90/Dr. Holly Batsell.png2020-10-02T07:00:00ZPhoenix Bio News
ASU professor receives Fulbright award to improve medical trainingASU professor receives Fulbright award to improve medical training<div class="ExternalClass1BE61456D0A444E8BCF4C235288AB66F"><html> <p>​</p> <span id="ms-rterangepaste-start"></span> <p style="box-sizing:border-box;margin:0px 0px 24px;max-width:800px;line-height:24px;color:rgb(42, 42, 42);font-family:roboto, "helvetica neue", helvetica, arial, sans-serif;font-size:16px;"> <a style="box-sizing:border-box;background:transparent;color:rgb(163, 0, 70);border-bottom:1px dotted rgb(163, 0, 70);transition:all 0.25s ease-in-out 0s;" href="https://isearch.asu.edu/profile/3181636" target="_blank"> <span style="box-sizing:border-box;">David Sklar</span> </a> <span style="box-sizing:border-box;">, a physician and professor at Arizona State University’s</span> <a style="box-sizing:border-box;background:transparent;color:rgb(163, 0, 70);border-bottom:1px dotted rgb(163, 0, 70);transition:all 0.25s ease-in-out 0s;" href="https://chs.asu.edu/" target="_blank"> <span style="box-sizing:border-box;"> College of Health Solutions</span> </a> <span style="box-sizing:border-box;">, has received a Fulbright U.S. Scholar Program award in medical education research and lecturing to work with faculty at the </span> <a style="box-sizing:border-box;background:transparent;color:rgb(163, 0, 70);border-bottom:1px dotted rgb(163, 0, 70);transition:all 0.25s ease-in-out 0s;" href="https://www.rcsi.com/dublin/" target="_blank"> <span style="box-sizing:border-box;">Royal College of Surgeons in Ireland</span> </a> <span style="box-sizing:border-box;"> to improve population health training for their medical students.</span> </p> <p style="box-sizing:border-box;margin:0px 0px 24px;max-width:800px;line-height:24px;color:rgb(42, 42, 42);font-family:roboto, "helvetica neue", helvetica, arial, sans-serif;font-size:16px;"> <span style="box-sizing:border-box;">Sklar, who is also a senior adviser to the ASU provost, will spend next summer in Ireland as part of a yearlong effort to develop a new curriculum for Royal College of Surgeons in Ireland students that advances knowledge and skills to improve overall individual and community health beyond basic diagnosis and treatment of disease. This includes teaching ways to lower health care costs, improve health care providers’ mental and physical well-being, and raise awareness about other factors that affect a patient’s health, such as socioeconomic status, education level, and the surrounding environment.</span> <span style="box-sizing:border-box;overflow:auto;border-top:none;border-bottom:none;padding-top:20px;padding-bottom:20px;margin-bottom:12.5px;margin-top:12.5px;width:371px;display:block;border-left:none;border-right:1px solid rgb(238, 238, 238);padding-right:20px;margin-right:25px;float:left;" class="image-with-caption image-with-caption-border-right image-with-caption-float-left"> <img class="" style="box-sizing:border-box;border-width:0px;border-style:initial;vertical-align:middle;max-width:100%;width:350px;margin:5px;" src="https://asunow.asu.edu/sites/default/files/styles/asu_news_article_image/public/sklar-david-0135_1.jpg?itok=Q2Hs_nTw" alt="David Sklar" /> <span style="box-sizing:border-box;margin-top:10px;color:rgb(118, 118, 118);font-size:13px;display:block;float:left;width:350px;" class="description">David Sklar.</span> <span style="box-sizing:border-box;margin-top:10px;color:rgb(118, 118, 118);font-size:13px;display:block;float:left;width:350px;" class="description"> <a style="box-sizing:border-box;background:transparent;color:rgb(163, 0, 70);border-bottom:1px dotted rgb(163, 0, 70);transition:all 0.25s ease-in-out 0s;" href="https://asunow.asu.edu/sites/default/files/sklar-david-0135_1.jpg" target="_blank">Download Full Image</a> </span> </span> </p> <p style="box-sizing:border-box;margin:0px 0px 24px;max-width:800px;line-height:24px;color:rgb(42, 42, 42);font-family:roboto, "helvetica neue", helvetica, arial, sans-serif;font-size:16px;"> <span style="box-sizing:border-box;">Because the Royal College of Surgeons in Ireland is a medical school that includes campuses in Ireland, Bahrain and Malaysia, with a student body from all over the world, this socio-ecological curriculum model promotes a global perspective in medical education that aims to motivate students to serve populations most in need of health care.</span> </p> <p style="box-sizing:border-box;margin:0px 0px 24px;max-width:800px;line-height:24px;color:rgb(42, 42, 42);font-family:roboto, "helvetica neue", helvetica, arial, sans-serif;font-size:16px;"> <span style="box-sizing:border-box;">“This model emphasizes the dynamic interplay of the individual and the various influences of family, community, health policy, the environment and other global effects,” Sklar said. “We will be integrating innovations that are being developed and tested all over the world and strive to match them with the unique interests and needs of (the college).” </span> </p> <p style="box-sizing:border-box;margin:0px 0px 24px;max-width:800px;line-height:24px;color:rgb(42, 42, 42);font-family:roboto, "helvetica neue", helvetica, arial, sans-serif;font-size:16px;"> <span style="box-sizing:border-box;">ASU Provost Mark Searle commended Sklar for his work to promote population health from a medical training perspective.</span> </p> <p style="box-sizing:border-box;margin:0px 0px 24px;max-width:800px;line-height:24px;color:rgb(42, 42, 42);font-family:roboto, "helvetica neue", helvetica, arial, sans-serif;font-size:16px;"> <span style="box-sizing:border-box;">“ASU is proud to contribute to global health through the Fulbright program and is confident that Dr. Sklar will improve international collaboration through his work on innovations in health professions education at the Royal College of Surgeons in Ireland,” he said.</span> </p> <p style="box-sizing:border-box;margin:0px 0px 24px;max-width:800px;line-height:24px;color:rgb(42, 42, 42);font-family:roboto, "helvetica neue", helvetica, arial, sans-serif;font-size:16px;"> <span style="box-sizing:border-box;">Sklar is one of more than 800 U.S. citizens who will conduct research and teach abroad through the Fulbright U.S. Scholar Program in the coming year. Since 1946, the Fulbright Program has enabled more than 390,000 students, scholars, artists, teachers and professionals of all backgrounds to study, teach and conduct research, exchange ideas and find solutions to shared international concerns. The program is sponsored by the U.S. government and is funded annually by the U.S. Department of State. ​</span> </p> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>2020-10-01T07:00:00ZASU
National Blue Ribbon School 2020National Blue Ribbon School 2020<div class="ExternalClassC9AE471B315A43DDAAE053AB6B84BE06"><html> <p>​</p> <span id="ms-rterangepaste-start"></span> <p style="font-family:montserrat, arial, sans-serif;font-size:19px;">The National Blue Ribbon Schools Program recognizes public and private elementary, middle, and high schools based on their overall academic excellence or their progress in closing achievement gaps among student subgroups. “Every year, the U. S. Department of Education seeks out and celebrates great American schools which demonstrate that all students can achieve to high levels. The coveted National Blue Ribbon School award affirms the hard work of students, educators, families, and communities in creating safe and welcoming schools where students master challenging and engaging content.” (<a style="cursor:pointer;" href="https://nationalblueribbonschools.ed.gov/background/" target="_blank">National Blue Ribbon School Website</a>) </p> <p style="font-family:montserrat, arial, sans-serif;font-size:19px;">“Bioscience High School, with Dr. Holly Batsell’s steady leadership for the past four years, is routinely ranked as one of the top high schools in Arizona, earning an “A” for the past two years”, said PXU Superintendent Dr. Chad Gestson. “With an emphasis on an integrated, rigorous curriculum while incorporating science, technology, engineering, and math, Dr. Batsell has successfully focused on increasing ACT scores and increasing student enrollment and retention. She has high expectations for herself and her staff.” Dr. Gestson continued, “these expectations have translated into a positive and supportive school culture. This, in turn, consistently promotes student success. Bioscience students receive hundreds of thousands of dollars in scholarships each year and many go on to successful STEM careers. The honor of being named a National Blue Ribbon School is a reflection of the hard work and dedication of all Bioscience staff.”​<br></p> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>2020-10-01T07:00:00ZCity of Phoenix
SINGLE-CELL RNA SEQUENCING REVEALS DETAILS ABOUT INDIVIDUAL CELLS IN PANCREATIC TUMORSSINGLE-CELL RNA SEQUENCING REVEALS DETAILS ABOUT INDIVIDUAL CELLS IN PANCREATIC TUMORS<div class="ExternalClassC5788228BE4A4D53B31356F7F1C02CD4"><html> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;float:left;width:855px;" class="col-md-12"> <ul style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;" class="list-inline posted-info"> <li style="box-sizing:border-box;border-radius:0px;display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;"> <div style="box-sizing:border-box;border-radius:0px;"> <span style="box-sizing:border-box;border-radius:0px;">​Written by</span> <span style="box-sizing:border-box;border-radius:0px;" class="uBlogsy_author_name"><a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;" title="Steve Yozwiak" href="https://www.tgen.org/news/?author=Steve+Yozwiak" target="_blank">Steve Yozwiak</a></span></div> </li> <li style="box-sizing:border-box;border-radius:0px;display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;">Posted Tuesday September 29, 2020</li></ul> <br> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <em style="box-sizing:border-box;border-radius:0px;">TGen and HonorHealth investigators suggest this granular analysis could lead to better treatments for pancreatic cancer patients</em> </p> </div> </div> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;float:left;width:855px;" class="col-md-12"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">SCOTTSDALE, Ariz. — Sept. 29, 2020 —</span> Led by the <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/" target="_blank">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.cityofhope.org/homepage" target="_blank">City of Hope</a>, and by <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.honorhealth.com/research" target="_blank">HonorHealth Research and Innovation Institute</a><span style="box-sizing:border-box;border-radius:0px;">, </span>an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">The study results were published today in the scientific journal <em style="box-sizing:border-box;border-radius:0px;">Genome Medicine</em>, a publication of <em style="box-sizing:border-box;border-radius:0px;">Springer</em> <em style="box-sizing:border-box;border-radius:0px;">Nature</em>.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Researchers used a relatively new technique known as single-cell sequencing to genetically identify cell types, and subtypes, that occur in pancreatic tumors, and identify the various cells in the tumor’s stroma, a substance surrounding the tumor that can hide the cancer from the body’s immune system.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">While single-cell transcriptomics has been used previously to study the cellular composition of primary tumor tissues of pancreatic ductal adenocarcinoma (PDAC), this study also used the technology to profile individual cells from dissociated primary tumors and biopsies of metastatic tissues, those cancerous lesions that have spread throughout the body from the primary tumor.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">This study was carried out in collaboration with investigators from <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.samsunghospital.com/gb/language/english/main/index.do" target="_blank">Samsung Medical Center</a> and City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases. Primary tumors and core needle biopsies of metastatic lesions from PDAC patients were sequenced using the Chromium single cell RNA-Seq platform.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Single-cell transcriptome analysis can offer important clinical insights on individual cell subpopulations and provide clues for developing novel therapeutic strategies for both targeted therapies and immunotherapies,” said <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.tgen.org/faculty-profiles/haiyong-han/" target="_blank">Haiyong Han</a>, Ph.D., a professor in TGen’s Molecular Medicine Division and head of the institute’s Pancreatic Cancer Research Laboratory.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Understanding the diversity and complexity of the PDAC tumor and stromal compartments in individual tumors may help identify unique intervention points and potentially inform treatment and maintenance strategies for patients with advanced disease,” said Dr. Han, the study’s senior author.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Distinct cell types and subtypes were identified in the analysis, including tumor cells, endothelial cells, cancer associated fibroblasts, and immune cells, and the expression levels of various genes in the individual cell populations correlated with patient clinical outcomes.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Working with our partners and colleagues by utilizing the technology of singe cell sequencing, we can continue to learn more about the biology of pancreas cancer.  These insights may potentially help us determine more treatment options for our patients,” said <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.honorhealth.com/physicians/erkut-borazanci" target="_blank">Erkut Borazanci</a>, M.D., M.S., a medical oncologist and physician-investigator at HonorHealth Research and Innovation Institute, a clinical associate professor at TGen, and one of the paper’s authors.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Pancreatic cancer is an aggressive disease that carries a high mortality rate. It is the third-leading cause of cancer death in the U.S., following lung and colorectal cancers. In 2020, the five-year survival rate for pancreatic cancer is only about 10%, though that represents progress from the dismal 6% rate in 2014.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Next, researchers plan to use more advanced single-cell spatial transcriptomics analysis to further investigate the cellular relationships related to survival rates using real-time methods. Broader use of this technology could potentially guide the search for new agents to treat pancreatic cancer. </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">For more information about pancreatic cancer research studies at HonorHealth Research and Innovation Institute, please visit <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://www.honorhealth.com/company/research-institute" target="_blank">HonorHealth.com/research</a>, call 480-323-1364 or email <a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="mailto:clinicaltrials@honorhealth.com" target="_blank">clinicaltrials@honorhealth.com</a>.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">This research was supported by: the National Foundation for Cancer Research; SU2C-CRUK-Lustgarten Foundation Pancreatic Dream Team Research Grant (SU2C-AACR-DT-20-16); Baylor Scott & White Research Institute (BSWRI) and Translational Genomics Research Institute (TGen) Collaboration in Oncology Research; and the Korean Health Technology R&D Project  (HI14C2640).</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">The study — <em style="box-sizing:border-box;border-radius:0px;"><a style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;" href="https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-020-00776-9" target="_blank">Single-Cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions</a> — </em>was published in the scientific journal <em style="box-sizing:border-box;border-radius:0px;">Genome Medicine</em>.</p> <br> <br> </div> </div> <p> <br> </p> </html></div>2020-09-29T07:00:00ZTGen
TGEN LAUNCHES VIDIUM ANIMAL HEALTHTGEN LAUNCHES VIDIUM ANIMAL HEALTH<div class="ExternalClassE31BAFC3FABC460DA9375CB91D510B3B"><html> ​ <span id="ms-rterangepaste-start"></span> <div class="row" style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"> <div class="col-md-12" style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;float:left;width:855px;"> <ul class="list-inline posted-info" style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;"> <li style="box-sizing:border-box;border-radius:0px;display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;"> <div style="box-sizing:border-box;border-radius:0px;"> <span style="box-sizing:border-box;border-radius:0px;">Written by</span> <span class="uBlogsy_author_name" style="box-sizing:border-box;border-radius:0px;"><a target="_blank" href="https://www.tgen.org/news/?author=Steve+Yozwiak" title="Steve Yozwiak" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);outline:0px !important;">Steve Yozwiak</a></span></div> </li> <li style="box-sizing:border-box;border-radius:0px;display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;">Posted Monday September 28, 2020</li></ul> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <em style="box-sizing:border-box;border-radius:0px;">TGen subsidiary offers genomic diagnostics in support of veterinary oncologists and pet parents treating canine cancer</em> </p> </div> </div> <div class="row" style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;"> <div class="col-md-12" style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;float:left;width:855px;"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <span style="box-sizing:border-box;border-radius:0px;font-weight:700;">PHOENIX, Ariz. — Sept. (28), 2020 —</span> After more than a decade of pioneering the study of naturally occurring cancer in pet dogs, the <a target="_blank" href="https://www.tgen.org/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Translational Genomics Research Institute (TGen)</a>, an affiliate of <a target="_blank" href="https://www.cityofhope.org/homepage" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">City of Hope</a>, announced today the commercial launch of <a target="_blank" href="http://vidiumah.com/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">Vidium Animal Health</a>, providing genomic-based precision-medicine to veterinary oncologists and pet parents.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">As a veterinarian, Vidium President Dr. David Haworth has seen first-hand the pain and concern that veterinarians and pet parents experience when a dog is diagnosed with cancer.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Vidium is built around the human-animal bond, and the fact that the majority of pet owners feel their pet is part of their family,” Dr. Haworth said. “When a pet is diagnosed with cancer, it can be a really scary time for everyone, so we want to offer the very best information, and hope, that science can offer.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">To increase a pets’ chance of survival, Vidium created <em style="box-sizing:border-box;border-radius:0px;">SearchLight DNA™</em>, a test designed specifically to identify any of the nearly 120 known cancer-associated genetic mutations in dogs, and use the molecular profile of misbehaving genes to help guide diagnosis and treatment.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Vidium Founder and Chief Science Officer Dr. Will Hendricks, an Assistant Professor in TGen’s Integrated Cancer Genomics Division, has spent much of the past decade dedicated to the pursuit of <a target="_blank" href="https://ccr.cancer.gov/comparative-oncology-program" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">comparative oncology</a>, the study of naturally occurring cancers in animals to better understand human cancers and vice versa.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“It’s clearly a two-way street, with both humans and dogs benefiting from the exchange,” he said.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">As a prime example, Dr. Hendricks points to <a target="_blank" href="https://www.tgen.org/news/2019/august/20/tgen-and-ohio-state-link-gene-to-canine-lung-cancer/?search=canine" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">a landmark 2019 study</a> conducted by TGen and The Ohio State University, which found that — like many women who develop a particular type of breast cancer — the same gene, HER2, also appears to play an important role in lung cancer in many dogs.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Vidium was born from our finding that the genetic underpinnings of canine cancers reflected the same fundamental science that allowed us to apply precision medicine toward treating human cancers,” Dr. Hendricks said. “Cancer gene mutations that have clinical importance in canine oncology are abundant, and with <em style="box-sizing:border-box;border-radius:0px;">SearchLight DNA</em> our goal is to equip veterinarians with the best information possible to help guide the clinical management of the dogs in their care.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Katie Banovich, Vidium’s Director of Operations, said the absence of genomic technology in the care of pets is a tremendous void that Vidium hopes to fill, but only with the participation of veterinarians and pet parents.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“Through application of multi-disciplinary genomic science, we want to position Vidium as a partner in the veterinary care team,” Banovich said. “We want to be a guide. We want to work with veterinarians.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;"> <em style="box-sizing:border-box;border-radius:0px;">SearchLight DNA</em> reports will be customized with technical language designed for clinicians and easier-to-understand lay language for pet parents that fully communicates the details of their pet’s condition.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">While Vidium’s efforts will initially be put toward canine cancer, its goal is to expand its genomic analysis to the treatment of other diseases, and other animals.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Beyond assisting with the diagnosis, prognosis and treatment of dogs with cancer, Vidium will play a continuing role in the discovery of new associations between gene mutations, specific types of cancers in specific breeds of dogs, and clinical outcomes.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">“We are going to play an active role in changing the landscape of veterinary care, both through expanding our understanding of genetic biomarkers, and by facilitating access to targeted therapeutics that may make a difference in specific genetic settings,” Dr. Hendricks said.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;">Vidium Animal Health is a subsidiary of TGen. Learn more at: <a target="_blank" href="http://vidiumah.com/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);outline:0px !important;">vidiumah.com</a>.​<br></p> </div> </div> <span id="ms-rterangepaste-end"></span> <p> <br> </p> </html></div>2020-09-28T07:00:00ZTGen
Genetic Sleuthing Reveals Multiple Introductions Of Coronavirus To ArizonaGenetic Sleuthing Reveals Multiple Introductions Of Coronavirus To Arizona<div class="ExternalClass840E64380487488DB78CAE3B569438B3"><html> <p>​<span class="submitted" style="box-sizing:border-box;color:rgb(119, 119, 119);font-size:0.75em;line-height:1.25;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;letter-spacing:0.08px;word-spacing:0.4px;"><span class="submitted-label" style="box-sizing:border-box;">By</span> <span class="name" style="box-sizing:border-box;text-transform:uppercase;"><a target="_blank" href="https://www.knau.org/people/melissa-sevigny" rel="author" style="box-sizing:border-box;color:rgb(61, 61, 61);line-height:inherit;background:transparent;">MELISSA SEVIGNY</a></span></span><span style="color:rgb(61, 61, 61);font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;letter-spacing:0.08px;word-spacing:0.4px;"> </span>​<br></p> <p> <span style="color:rgb(61, 61, 61);font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;letter-spacing:0.08px;word-spacing:0.4px;">A</span><a style="box-sizing:border-box;color:rgb(22, 141, 217);line-height:inherit;background:transparent;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;letter-spacing:0.08px;word-spacing:0.4px;" target="_blank" href="https://mbio.asm.org/content/11/5/e02107-20"> new study</a><span style="color:rgb(61, 61, 61);font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;letter-spacing:0.08px;word-spacing:0.4px;"> shows the virus that causes COVID-19 arrived in Arizona in at least eleven separate introductions in February and March. That’s the result of genetic detective work done by scientists at Arizona’s three state universities and the Translational Genomics Research Institute in Flagstaff. KNAU’s Melissa Sevigny spoke with Jolene Bowers of TGen North about how sequencing the genome of the coronavirus can help public health professionals track the disease through time and space.</span><br> </p><span id="ms-rterangepaste-start"></span><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;"><span style="box-sizing:border-box;font-weight:700;line-height:inherit;">What can you learn from looking at the genetic material of the coronavirus?</span></p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;">What we’re doing is we’re sequencing a whole bunch of virus genomes to try to understand how the virus is spreading in and around Arizona. The way we do that is we’re sequencing these genomes and looking for these small mutations that will tell us who is related to whom. These mutations are constantly happening. They’re being passed down from generation to generation. So when we see two viruses that share a certain mutation, then we can be confident that they’re related.</p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;"><span style="box-sizing:border-box;font-weight:700;line-height:inherit;">So you sequenced the genome of the very first case in Arizona, and what did you learn from that?</span></p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;">Actually the CDC sequenced that first case… This was in late January. A young man was returning from travel and he presented to a health care center with mild symptoms…. He was very quickly diagnosed and quarantined… We were able to show that none of the viruses that we sampled in Arizona were related to that virus genome at all… So public health response efforts really work.</p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;"><span style="box-sizing:border-box;font-weight:700;line-height:inherit;">So you’ve sequenced many more genomes since that first case happened in January. What have you learned since then?</span></p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;">What we were able to show is a lot of our viruses in Arizona are most closely related to other viruses that are circulating in other states in the United States…. And we determined that very likely the virus was introduced into Arizona probably in mid to late February, but we didn’t start seeing it until cases starting coming to light in early and mid-March…. This was when the virus really started taking off in Arizona, and it probably all arrived here through domestic travel. Probably not surprising because that was when some of the travel restrictions were put in place and international travel was being discouraged.</p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;"><span style="box-sizing:border-box;font-weight:700;line-height:inherit;">One of the things your team discovered was that there were at least 11 separate introductions of the virus to Arizona. I’m curious, did that surprise you or were you expecting that?</span></p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;">It’s not surprising at all that we had that many virus introductions into Arizona. Arizona’s not in a bubble and people are still moving around. What did surprise me is we were able to detect at least 11 different introductions to the virus. Because the way we’re doing that, we’re comparing the genomes of the virus, so these genomes have to be different enough to detect these differences in the virus, so we can trace these lineages or these variants of these viruses back to different ancestors. That’s how we determined there were probably at least 11 introductions. We think that’s probably an underestimate really.</p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;"><span style="box-sizing:border-box;font-weight:700;line-height:inherit;">What are the next steps, or questions you still want to answer?</span></p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;">We definitely want to take another big picture look now that we have thousands of genomes sequenced and see how the pandemic has evolved in Arizona, Do we see any of these super spreader events? One of our major goals is really to demonstrate the value of this genomic epidemiology and make it routine, so that it becomes an everyday thing.</p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;"><span style="box-sizing:border-box;font-weight:700;line-height:inherit;">Jolene Bowers, thank you for speaking with me today.</span></p><p style="box-sizing:border-box;margin:0px 0px 1.5625rem;padding:0px;font-family:lato, "helvetica neue", helvetica, helvetica, arial, sans-serif;font-size:16px;line-height:1.75em;text-rendering:optimizelegibility;color:rgb(61, 61, 61);letter-spacing:0.08px;word-spacing:0.4px;">Thank you for having me.​<br></p><span id="ms-rterangepaste-end"></span><p><br></p> </html></div>2020-09-25T07:00:00ZNAU
NewsletterNewsletter<div class="ExternalClassDD13B7C84EFB4E83B3554560B99C9073"><html> <p>​</p> <span id="ms-rterangepaste-start"></span> <div class="bgcolor" style="background-color:rgb(230, 230, 230);"> <table class="bgimage" width="100%" border="0" cellpadding="0" cellspacing="0" bgcolor="#e6e6e6" style="border-collapse:collapse;table-layout:auto;"> <tbody> <tr> <td align="center"> <table class="main-width" width="690" align="center" border="0" cellpadding="0" cellspacing="0" style="border-collapse:collapse;table-layout:fixed;width:690px;"> <tbody> <tr> <td class="layout" align="center" valign="top" style="padding:15px 5px;"> <table width="100%" align="center" border="0" cellpadding="0" cellspacing="0" style="border-collapse:collapse;table-layout:fixed;"> <tbody> <tr> <td class="layout-container-border" align="center" valign="top" bgcolor="#56a6ad" style="background-color:rgb(86, 166, 173);padding:0px;"> <table width="100%" align="center" border="0" cellpadding="0" cellspacing="0" bgcolor="#56a6ad" style="border-collapse:collapse;table-layout:fixed;"> <tbody> <tr> <td class="layout-container" align="center" valign="top" bgcolor="#ffffff" style="background-color:rgb(255, 255, 255);padding:0px;"> <div class=""> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class=" editor-col OneColumnMobile" width="100%" align="" valign="top"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);text-align:center;display:block;line-height:1.2;padding:10px 40px;"> <div class="text-container galileo-ap-content-editor"> <div align="left" style="text-align:left;"> <span style="font-size:22px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:22px;font-weight:bold;"> </span> <span style="font-size:22px;font-weight:bold;color:rgb(235, 169, 66);">TODAY</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-style:italic;font-weight:bold;">An Update on the People, Places, and Possibilities of the Phoenix Biomedical Campus in Downtown Phoenix • Oversight provided by Arizona State University (Michael Crow, President), Northern Arizona University (Rita Cheng, President), University of Arizona (Robert Robbins, President), Arizona Board of Regents (John Arnold, Executive Director), and City of Phoenix led by Mayor Kate Gallego • September 22, 2020</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">In the photograph in our masthead, Dr. Cara Christ, director of the Arizona Department of Health Services, joined Arizona Governor Doug Ducey and other local health leaders to announce </span> <a href="https://azgovernor.gov/governor/news/2020/08/governor-ducey-and-health-leaders-urge-arizonans-get-flu-shot" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">important next steps</a> <span style="font-size:12px;color:rgb(0, 0, 0);"> vaccinating more Arizonans against the flu as we continue to mitigate the spread of COVID-19. The press conference was held at the Virginia G. Piper Auditorium in historic Building 2 of the University of Arizona College of Medicine–Phoenix. Since its renovation in the mid-2000s, the auditorium is a special Phoenix Biomedical Campus and Downtown Phoenix gathering place for events, meetings, classes, and student activities.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Bioscience advocates share stories on responding to COVID-19</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">Tune in to watch “</span> <a href="https://youtu.be/KYYn1a1fiZU" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Celebrating Life & Science</a> <span style="font-size:12px;color:rgb(0, 0, 0);">,” an inspirational and educational program highlighting how Arizona's bioscience community is working together to make life better before, during, and after COVID-19. The guest speakers joining host Joan Koerber-Walker, President & CEO of the Arizona Bioindustry Association (AZBio), include:</span> </div> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;">Doug Ducey, Governor, State of Arizona</li> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;">Dr. Jeffrey Trent, President & Research Director, TGen</li> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;">Dr. Joshua LaBaer, Executive Director, ASU Biodesign Institute</li> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;">Sandra Watson, President & CEO, Arizona Commerce Authority (ACA)</li> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;">Michelle McMurry-Heath, President & CEO, Biotechnology Innovation Organization</li> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;">Dr. Rosa Krajmalnik-Brown, Arizona Bioscience Researcher of the Year</li> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;">Dr. Carl Yamashiro, Arizona Bioscience Educator of the Year</li> </ul> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Starting at 28:00 into the hour-long program is a visual tour of the Phoenix Biomedical Campus</span> <span style="font-size:12px;color:rgb(0, 0, 0);font-weight:bold;">.</span> <span style="font-size:12px;color:rgb(0, 0, 0);"> “Celebrating Life & Science” is presented by AZBio and ACA with additional support from the City of Phoenix and Flinn Foundation.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC Partner Spotlight: Northern Arizona University</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">Numerous companies, organizations, and higher education institutions call the Phoenix Biomedical Campus home. Starting today, we’ll shine a spotlight on recent news of an individual PBC partner. In this issue, Northern Arizona University.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">For the Fall 2020 academic calendar, NAU’s Athletic Training (AT) Program welcomed 18 new students, Occupational Therapy (OT) welcomed 45 students, and both Physical Therapy (PT) and Physician Assistant Studies (PAS) welcomed 50.</span> </div> <div align="left"> <br> </div> <div align="left"> <span style="font-size:12px;color:rgb(0, 0, 0);">The PAS Class of 2021 began its first day of clinical rotations on the front lines on August 24. The deadline to apply for the Class of 2023 was September 1. Over 3,000 applications were received. The PAS program was awarded an Area Health Education Center/Rural Health Professions Program (AHEC/RHPP) grant totaling $243,338. This grant supports student placement during the clinical year in medically underserved communities with an emphasis on rural areas. AHEC and RHPP students are supported with travel, lodging, and meal stipends during select clinical rotations. PA students are also supported with additional academic resources for point-of-care decision-making and reference tools on their mobile units. For more information about NAU at the PBC, </span> <a href="https://nau.edu/phoenix-biomedical-campus" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">click here</a> <span style="font-size:12px;color:rgb(0, 0, 0);">.</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PEOPLE </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Noteworthy individuals making a difference</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.azregents.edu/news-releases/david-krietor-appointed-phoenix-biomedical-campus%e2%80%99-first-executive-director" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">David Krietor appointed as PBC’s first executive director</a> (ABOR, 08-28-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.azregents.edu/news-releases/applications-open-regents%e2%80%99-cup-event-debate-competition-celebrates-free-speech-offers" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">ABOR accepting applications for the Regents’ Cup, a student debate competition celebrating free speech, civil discourse, and democratic engagement</a> (ABOR, 09-02-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PLACES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Properties and new developments where good things happen</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.azcentral.com/in-depth/news/local/arizona-science/2020/09/13/bioscience-and-health-care-industries-expand-and-add-jobs-phoenix/3392691001/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Phoenix invests big in health care and biosciences, hoping to boost economy and add jobs</a> (Arizona Republic, 09-16-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.bizjournals.com/losangeles/news/2020/09/01/thriving-life-sciences-sector-demands-strategic-r.html" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Thriving life sciences sector demands strategic real estate knowledge</a> (Phoenix Business Journal, 09-01-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">POSSIBILITIES </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- Significant research & educational opportunities going on</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://crowdfund.foundationnau.org/project/21729/updates/1" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">NAU Department of Occupational Therapy launches new program, “OT Easing the Transition: An independent living skills curriculum for youth aging out of foster care”</a> (NAU Foundation, 09-01-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://asunow.asu.edu/20200818-solutions-identifying-facts-sex-trafficking-and-internet" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Identifying the facts on sex trafficking and the internet</a> (ASU, 08-18-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="http://news.nau.edu/racial-disparities/#.X1KLkGepFE5" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Examining the role racial disparities play in mortality rates of rural, urban residents</a> (NAU, 08-06-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://asunow.asu.edu/20200709-discoveries-why-hydration-so-important-when-hiking-heat-summer" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Why hydration is so important when hiking in the heat of summer</a> (ASU, 07-09-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://asunow.asu.edu/20200611-arizona-impact-study-finds-correlation-between-vaccination-rates-disease-immunity" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Study finds correlation between vaccination rates, disease immunity</a> (ASU, 06-11-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://asunow.asu.edu/20200428-solutions-personalized-education-key-deploying-nurses-icu-0" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Personalized education key to deploying nurses to ICU</a> (ASU, 04-28-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://asunow.asu.edu/20200424-solutions-fighting-burnout-facebook-asu-grad-student" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Fighting burnout with Facebook</a> (ASU, 04-24-20)</li> </ul> <div align="left"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;text-align:left;font-size:12px;color:rgb(0, 0, 0);"> <a href="https://asunow.asu.edu/20200408-discoveries-why-older-adults-really-should-drink-their-health" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Why older adults really should drink to their health</a> (ASU, 04-10-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class=" editor-col OneColumnMobile" width="100%" align="" valign="top"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);text-align:center;display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left" style="text-align:left;"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PANDEMIC RESPONSE</span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">- </span> <span style="font-size:12px;font-weight:bold;color:rgb(83, 102, 127);">PBC-affiliated experts weigh in on timely issue</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class=" editor-col OneColumnMobile" width="100%" align="" valign="top"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);text-align:center;display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.medscape.com/viewarticle/937468" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Should social distancing measures be enforced?</a> (Medscape, 09-16-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://eurekalert.org/pub_releases/2020-09/ttgr-acg091420.php" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Arizona COVID-19 Genomics Union tracks strains of SARS-CoV-2</a> (TGen, 09-15-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.nbcnews.com/news/latino/arizona-pulmonologist-dr-thomas-ardiles-says-americans-have-unite-beat-n1239812" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Arizona pulmonologist Dr. Thomas Ardiles says Americans have to unite to beat coronavirus “war”</a> (NBC News, 09-14-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.biospace.com/article/releases/coronavirus-breakthrough-senhwa-reports-first-eind-silmitasertib-treated-severe-covid-19-patient-discharged-following-five-days-of-treatment/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Senhwa reports first eIND Silmitasertib treated severe COVID-19 patient discharged following five days of treatment</a> (Biospace, 09-11-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.azcentral.com/story/entertainment/life/health/2020/09/10/is-it-safe-get-haircut-go-to-dentist-eat-at-restaurant-use-public-bathroom-go-to-gym-covid-19/5717730002/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Is it safe to get a haircut? Here are the risks of 5 everyday activities during COVID-19</a> (Arizona Republic, 09-10-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://kjzz.org/content/1616693/brain-fog-one-lingering-symptoms-covid-19" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">“Brain Fog” one of the lingering symptoms of COVID-19</a> (KJZZ, 09-09-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://kjzz.org/content/1616179/older-adults-often-left-out-clinical-trials-vaccines" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Older adults often left out of clinical trials for vaccines</a> (KJZZ, 09-07-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://academic.oup.com/ppar/advance-article/doi/10.1093/ppar/praa024/5901344?guestAccessKey=649b431f-030d-4b09-83bb-4a654af0e7fd" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Addressing the needs of rural caregivers of individuals with Alzheimer’s Disease and related dementias during and beyond COVID-19</a> (Gerontological Society of America, 09-04-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://kjzz.org/content/1615597/dont-repeat-mistakes-memorial-day-weekend-public-health-expert-warns-against-rise" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Public health expert warns against rise in Arizona's COVID-19 cases</a> (KJZZ, 09-04-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.azfamily.com/news/arizona_schools/phoenix-area-doctor-weighs-in-on-hybrid-instruction-holiday-weekend-safety/article_d0979790-ee58-11ea-99ab-a3b0783a65a2.html" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Phoenix-area doctor weighs in on hybrid instruction, holiday weekend safety during COVID-19</a> (AZ Family, 09-03-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://kjzz.org/content/1614359/herd-immunity-isnt-smart-strategy-fighting-covid-19-more-arizona-businesses-open" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">“Herd Immunity” isn't smart strategy for fighting COVID-19 as more Arizona businesses open</a> (KJZZ, 09-01-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://azbigmedia.com/business/psychiatrist-here-are-covid-19-and-mental-health-concerns-as-kids-go-back-to-school/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Psychiatrist: Here are COVID-19 and mental health concerns as kids go back to school</a> (AZ Big Media, 08-31-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://www.12news.com/article/news/how-to-combat-possible-screen-time-related-health-challenges-for-kids/75-616cf31b-8eb4-447c-bdf4-f3a2787c2a3f" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">How to combat possible screen time related health challenges for kids during COVID-19</a> (12 News, 08-31-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;font-size:12px;color:rgb(0, 0, 0);text-align:left;"> <a href="https://azbigmedia.com/business/preparing-for-flu-season-during-covid-19/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">Preparing for flu season during COVID-19</a> (AZ Big Media, 08-31-20)</li> </ul> <div align="left" style="text-align:left;"> <br> </div> <ul style="padding:0px;margin:0px 0px 0px 40px;"> <li style="padding:0px;margin:0px;line-height:1.2;text-align:left;font-size:12px;color:rgb(0, 0, 0);"> <a href="https://asunow.asu.edu/20200624-solutions-asu-faculty-respond-global-health-crisis-innovative-ideas" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;color:rgb(0, 0, 0);">ASU faculty respond to global health crisis with innovative ideas</a> (ASU, 06-24-20)</li> </ul> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="center-text content editor-col OneColumnMobile" width="100%" align="left" valign="top" style="text-align:center;"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text center-text content-text" align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div align="left"> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">PBC</span> <span style="font-size:12px;font-weight:bold;"> </span> <span style="font-size:12px;font-weight:bold;color:rgb(235, 169, 66);">PARTICULARS</span> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class=" editor-col OneColumnMobile" width="100%" align="" valign="top"> <div class="gl-contains-text"> <table width="100%" cellpadding="0" cellspacing="0" border="0" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="editor-text editor-text " align="left" valign="top" style="font-family:verdana, geneva, sans-serif;font-size:14px;color:rgb(46, 47, 47);display:block;line-height:1.2;padding:10px 40px;"> <div></div> <div class="text-container galileo-ap-content-editor"> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Contact:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <span style="font-size:12px;color:rgb(0, 0, 0);">David Krietor, Executive Director, 602-741-5580, </span> <a href="mailto:david.krietor@asu.edu" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">david.krietor@asu.edu</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Website:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__biomedicalphoenix.com_&d=DwMFaQ&c=l45AxH-kUV29SRQusp9vYR0n1GycN4_2jInuKy6zbqQ&r=ZkOduS1eiLUbvWLZ-8ug9vL9jHDR32Y_z26zPsk2vak&m=-wKoE3rm1i95DXGiQyqWJla6ia5YA9fsFMAO4vC9trM&s=XmoGrKj6ux3_Hjm5HLDxe1wzR5CGHEalThzpBkYVG90&e=" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">biomedicalphoenix.com</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="mailto:claudia.whitehead@phoenix.gov" rel="noopener noreferrer" target="_blank" style="font-size:12px;color:rgb(0, 0, 0);">Claudia Whitehead</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="mailto:claudia.whitehead@phoenix.gov" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">claudia.whitehead@phoenix.gov</a> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Events Calendar:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a href="https://asuevents.asu.edu/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">ASU</a> <span style="font-size:12px;color:black;">, </span> <a href="https://www.pxu.org/Page/38" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Bioscience H.S.</a> <span style="font-size:12px;color:black;">, </span> <a href="https://events.nau.edu/?view=grid&search=y" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">NAU</a> <span style="font-size:12px;color:black;">, </span> <a href="https://puhsaa.com/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">PUHS Alumni Assoc.</a> <span style="font-size:12px;color:black;">, </span> <a href="https://www.tgen.org/giving/events/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">TGen</a> <span style="font-size:12px;color:black;">, </span> <a href="https://uahs.arizona.edu/events" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">UArizona</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Jobs:</span> <span style="font-size:12px;color:rgb(0, 0, 0);"> </span> <a href="https://careers.insidehighered.com/jobs/?Keywords=%22phoenix+biomedical+campus%22#browsing" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Inside Higher Ed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://www.indeed.com/jobs?q=%22phoenix%20Biomedical%20Campus%22&l=Phoenix%2c%20AZ&radius=0&vjk=9d8bff47682c0b93" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Indeed</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://jobs.azbio.org/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">AZBio Job Center</a> </div> <div> <br> </div> <div> <span style="font-size:12px;color:rgb(83, 102, 127);font-weight:bold;">Getting Around:</span> <span style="font-size:12px;color:rgb(83, 102, 127);"> </span> <a href="https://phoenixmed.arizona.edu/campus" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Campus Map</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://www.valleymetro.org/maps-schedules" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Public Transit</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="http://gridbikes.com/" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Bike Share</a> <span style="font-size:12px;color:rgb(0, 0, 0);">, </span> <a href="https://parking.arizona.edu/parking/biomedical-campus/index.php?referral=compurchase" rel="noopener noreferrer" target="_blank" style="text-decoration-line:underline;font-size:12px;color:rgb(0, 0, 0);">Parking</a> </div> </div> </td> </tr> </tbody> </table> </div> </td> </tr> </tbody> </table> <table width="100%" cellpadding="0" cellspacing="0" border="0" class="galileo-ap-layout-editor" style="border-collapse:collapse;table-layout:fixed;min-width:100%;"> <tbody> <tr> <td class="divider-container editor-col 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Women in Medicine Fighting COVID-19: Drs. Hale, Herbst-Kralovetz and MahnertWomen in Medicine Fighting COVID-19: Drs. Hale, Herbst-Kralovetz and Mahnert<div class="ExternalClass3FD55060215B483CB856C46289507452"><html>​<span id="ms-rterangepaste-start"></span><h5 style="box-sizing:border-box;margin-top:0px;margin-bottom:0px !important;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:normal;line-height:18px;color:rgb(155, 155, 155);font-size:15px;margin-right:0.5rem !important;text-transform:uppercase !important;font-style:normal;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="field_title text-uppercase mb-0 mr-2"><span style="box-sizing:border-box;" class="field field--name-title field--type-string field--label-hidden">TERESA JOSEPH</span></h5><h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"><span id="ms-rterangecursor-start"></span><span id="ms-rterangecursor-end"></span>​<br></h4><h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"><div style="box-sizing:border-box;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;color:rgb(33, 33, 33) !important;font-size:1.25rem;font-style:normal;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="field field--name-field-subtitle field--type-string field--label-hidden h5 mb-lg-3 text-dark field__item">Collaborative Research Analyzes Impact of Stress, Pregnancy and COVID-19</div></h4><div style="box-sizing:border-box;color:rgb(96, 96, 96);font-size:15px;line-height:20px;margin-bottom:3rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><em>In honor of this year’s <a href="https://phoenixmed.arizona.edu/diversity/wims" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;" target="_blank">Women in Medicine and Science</a> month, the University of Arizona College of Medicine – Phoenix has asked a few faculty to share their inspiring stories and work that is helping our community through the <a href="https://phoenixmed.arizona.edu/covid-19" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;" target="_blank">coronavirus pandemic</a>.</em></p></h4><h2 style="box-sizing:border-box;margin-top:0px;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;color:rgb(30, 82, 136);">Meet Drs. Hale, Herbst-Kralovetz and Mahnert</h2><h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Three faculty members at the University of Arizona College of Medicine – Phoenix are working on a highly collaborative research project related to the COVID-19 pandemic, stress and pregnancy.</p><figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:250px;height:auto;background-color:rgb(232, 237, 243) !important;"><div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"><img data-entity-type="file" data-entity-uuid="ce39543b-ef6e-4b31-a7ff-6009b25382a9" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/hale-story_0.jpg" alt="Taben Hale, PhD" style="margin:5px;border:0px;width:142px;vertical-align:middle;max-width:100%;box-sizing:border-box;" class="img-fluid" title="Taben Hale, PhD" /></div><figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;display:block;font-size:14px;color:rgb(96, 96, 96);margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;line-height:20px;"><em style="box-sizing:border-box;">Taben Hale, PhD</em></figcaption></figure><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The research is being conducted by Melissa Herbst-Kralovetz, PhD, an associate professor in<span> </span><a href="https://phoenixmed.arizona.edu/bms" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;" target="_blank">Basic Medical Sciences</a><span> </span>and<span> </span><a href="https://phoenixmed.arizona.edu/obgyn" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;" target="_blank">Obstetrics and Gynecology</a>, Taben Hale, PhD, an associate professor in<span> </span><a href="https://phoenixmed.arizona.edu/bms" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;" target="_blank">Basic Medical Sciences</a>, and Nichole Mahnert, MD, a clinical assistant professor in<span> </span><a href="https://phoenixmed.arizona.edu/obgyn" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;" target="_blank">Obstetrics and Gynecology</a>.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">The collaborative study began from a graduate medical education project. Obstetrics and Gynecology residents complete a research project over the course of their four-year training. First-year resident Dr. Bryan Grover’s interest in maternal-fetal medicine and translational science inspired this project. He asked how COVID-19 infections affect a woman’s pregnancy and fetus. To tackle this question, a highly collaborative team was assembled with an infectious disease/ reproductive immunologist (Dr. Herbst-Kralovetz), maternal stress/cardiovascular researcher (Dr. Hale), OB/GYN and surgeon (Dr. Mahnert) and Dr. Grover.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><strong style="box-sizing:border-box;font-weight:bolder;">Describe the research in layman’s terms.</strong></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">We are interested in studying the impact of maternal stress, SARS-CoV-2 infection on pregnancy and newborn outcomes. We know that maternal stress can have a negative health impact on fetal development and future disease risk in adulthood. In this study, we are interested in evaluating how the COVID-19 pandemic impacts pregnant moms and their babies. As we have learned over the past several months, SARS-CoV-2 infection affects multiple organ systems including cardiovascular function and can have long-term health effects. Stress also causes global health effects and can exacerbate underlying health issues by increasing inflammation. In this study, we aim to evaluate the impact of pandemic stress and SARS-CoV-2 infection on maternal health and newborn offspring by measuring signatures of stress and inflammation.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Even in the absence of SARS CoV-2 infection, there is a significant degree of added stress due to the pandemic. The stress associated with fear of contracting the virus, added pressures of working from home, and managing remote learning for other children all result in an increased burden on the mother and associated risk to fetal development and long-term health.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><strong style="box-sizing:border-box;font-weight:bolder;"></strong></p><figure class="bg-light figure img-fluid align-left" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 1rem 1rem 0px;float:left;max-width:250px;height:auto;background-color:rgb(232, 237, 243) !important;"><strong style="box-sizing:border-box;font-weight:bolder;"><div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"><img data-entity-type="file" data-entity-uuid="bef0696e-a3d3-4714-9f02-f1d0fea3416b" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/herbst-kralovetz-story_0.jpg" alt="Melissa Herbst-Kralovetz, PhD" style="margin:5px;border:0px;width:226px;vertical-align:middle;max-width:100%;box-sizing:border-box;" class="img-fluid" title="Melissa Herbst-Kralovetz, PhD" /></div><figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;display:block;font-size:14px;color:rgb(96, 96, 96);margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;line-height:20px;"><em style="box-sizing:border-box;">Melissa Herbst-Kralovetz, PhD</em></figcaption></strong></figure><strong style="box-sizing:border-box;font-weight:bolder;">Why is this research important?</strong><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">This has potential long-term impact on women and their babies. It is important that we study how the pandemic stress and SARS-CoV-2 infection impacts health outcomes during pregnancy and beyond. The health outcomes we are interested in studying touch on some of those organ systems, including indicators of stress and inflammation, as well as cardiovascular outcomes.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">There is ample evidence that the in utero environment can have long-term consequences on cardiovascular function and future disease risk. We know that prenatal stress can lead to altered blood pressure and heart rate regulation, as well as increased risk of depression and anxiety in adults. Understanding the impact of COVID on maternal stress and fetal development will lead to improved care of the maternal-fetal dyad.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><strong style="box-sizing:border-box;font-weight:bolder;">What is the research goal?</strong></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">We are interested in understanding the level to which pandemic stress and/or SARS-CoV-2 infection increases inflammation or stress markers in pregnant moms and their newborns. Inflammation and markers of stress could be a driver for adverse effects on women and their offspring.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><strong style="box-sizing:border-box;font-weight:bolder;">What do you want our community to know about this?</strong></p><figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:250px;height:auto;background-color:rgb(232, 237, 243) !important;"><strong style="box-sizing:border-box;font-weight:bolder;"><div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"><img data-entity-type="file" data-entity-uuid="96b25183-92ff-4a1d-99c0-c79469f9172b" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/mahnert-story.jpg" alt="Nichole Mahnert, MD" style="margin:5px;border:0px;width:166px;vertical-align:middle;max-width:100%;box-sizing:border-box;" class="img-fluid" title="Nichole Mahnert, MD" /></div><figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;display:block;font-size:14px;color:rgb(96, 96, 96);margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;line-height:20px;"><em style="box-sizing:border-box;">Nichole Mahnert, MD</em></figcaption></strong></figure><strong style="box-sizing:border-box;font-weight:bolder;"></strong><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Studies have shown that women are experiencing elevated symptoms of anxiety and depression during the COVID-19 pandemic relative to pre-pandemic pregnancy cohorts. As such, these stress levels could have long-term health impacts on their children. Healthy lifestyle factors could help to mitigate these negative effects and include social support and exercise.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Mindfulness, yoga and other stress reduction techniques are more important than ever. Thus far, the risk of transmission of COVID-19 from mom to fetus is unlikely, but further research on this topic is so important, which is part of why we are doing this study.</p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"><strong style="box-sizing:border-box;font-weight:bolder;">Why did you want to study this?</strong></p><p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">We know women are bearing the burden of caregiving stress and are disproportionately impacted during pandemics over the course of history. That stress could be having a negative impact on women’s health, including during pregnancy. There are so many unknowns with COVID-19 pandemic and we would like to contribute to expanding our knowledge base and the impact it is having on women’s health.</p></h4></div><h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"><br><br></h4><p><br></p></html></div>https://biomedicalphoenix.com/Lists/News/Attachments/83/hale-feature.jpg2020-09-18T07:00:00ZUA
Celebrating Life & Science in ArizonaCelebrating Life & Science in Arizona<div class="ExternalClassBA1ACB881CD54EDEAAF0AA6E6E6F9EFC"><html> <p>​Watch <span style="color:#444444;">Celebrating Life & Science for inspiring stories of Arizonans working together and using science to make life better before, during and after the COVID-19 emergency. </span><a href="https://www.youtube.com/AZBio1" target="_blank">https://www.youtube.com/AZBio1</a> <span style="color:#444444;">​</span></p> <p><br></p></html></div>2020-09-17T07:00:00ZArizona BioIndustry Assoc
NCI FUNDS RESEARCH INTO WHY GLIOBLASTOMA HITS MALES HARDER THAN FEMALESNCI FUNDS RESEARCH INTO WHY GLIOBLASTOMA HITS MALES HARDER THAN FEMALES<div class="ExternalClass3D6E76197F37431295ACCB487936F28B"><html> <p>​</p> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <ul style="box-sizing:border-box;border-radius:0px;margin-top:0px;margin-bottom:10px;padding-left:0px;margin-left:-5px;list-style:none;" class="list-inline posted-info"> <li style="box-sizing:border-box;border-radius:0px;color:rgb(85, 85, 85);display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;"> <div style="box-sizing:border-box;border-radius:0px;"> <span style="box-sizing:border-box;border-radius:0px;">Written by</span> <span> </span> <span style="box-sizing:border-box;border-radius:0px;" class="uBlogsy_author_name"> <a href="https://www.tgen.org/news/?author=Steve+Yozwiak" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(85, 85, 85);text-decoration:none;outline:0px !important;" title="Steve Yozwiak" target="_blank"> <span style="box-sizing:border-box;border-radius:0px;">Steve Yozwiak</span> </a> </span> </div> </li> <span> </span> <li style="box-sizing:border-box;border-radius:0px;color:rgb(85, 85, 85);display:inline-block;padding-right:5px;padding-left:5px;font-style:italic;">Posted Thursday September 17, 2020</li> </ul> </h4> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <em style="box-sizing:border-box;border-radius:0px;">​<span id="ms-rterangecursor-start"></span><span id="ms-rterangecursor-end"></span>TGen technology is key to brain cancer research consortium led by Cleveland Clinic and Case Western Reserve University</em> </p> </h4> </div> </div> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <div style="box-sizing:border-box;border-radius:0px;margin-right:-15px;margin-left:-15px;color:rgb(85, 85, 85);font-family:"helvetica neue", helvetica, arial, sans-serif;font-size:14px;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="row"> <div style="box-sizing:border-box;border-radius:0px;min-height:1px;padding-right:15px;padding-left:15px;" class="col-md-12"> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <strong style="box-sizing:border-box;border-radius:0px;font-weight:700;">PHOENIX, Ariz. — Sept. 17, 2020 —</strong> <span> </span>The<span> </span><a href="https://www.tgen.org/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);text-decoration:none;outline:0px !important;" target="_blank">Translational Genomics Research Institute (TGen)</a>, an affiliate of<span> </span><a href="https://www.cityofhope.org/homepage" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);text-decoration:none;outline:0px !important;" target="_blank">City of Hope</a>, will employ two relatively new technologies in a study led by Cleveland Clinic Lerner Research Institute and Case Western Reserve University School of Medicine into why men are stricken with glioblastoma brain cancer far more often than women, and why women survive the disease almost twice as long as men.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">As part of a five-year $10.4 million grant announced today from the National Cancer Institute (NCI), researchers will delve into the molecular-level biology of glioblastoma — the most common and deadliest adult brain tumor — seeking new therapies against the disease.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">“We’ve known for some time that glioblastoma multiforme (GBM) affects men more than women,” said<span> </span><a href="https://www.tgen.org/faculty-profiles/michael-berens/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);text-decoration:none;outline:0px !important;" target="_blank">Dr. Michael Berens</a>, a TGen Deputy Director and Head of the institute’s Glioma Research Lab. “It’s been in front of us all along. We just haven’t taken a deep enough dive to appreciate in what ways they are different, and — more significantly from a precision-medicine perspective — how the sex of the patient might inform tailored treatment strategies.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Dr. Berens will study the tumor microenvironment, and the effect of immune cells on the tumor. A major goal of the study is to find out how to make the normal host cells in the brain more resilient against the tumor; specifically how women respond to the disease, and how to apply those findings to provide better treatment outcomes for men.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">First, TGen will employ “single-cell transcriptomics,” which will enable researchers to genetically identify every type of cell that occurs in the tumor, and identify all of the various normal brain cells that surround the tumor.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Then, for the first time in GBM, TGen will use a new technology called “spatial transcriptomics,” which will show the locations of the various cells and how they interact with each other.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">“We will be able to see who is there, who is misbehaving, who is next to who and, hopefully, who is influencing who,” Dr. Berens said of the various cellular interactions his team will investigate.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Two specific questions Dr. Berens wants to answer are: Why brain tumor cells connect with neurons, the functioning cells of the brain that determine memory and action; and why brain tumor cells appear to recruit special blood cells from bone marrow known as Myeloid Derived Suppressor Cells (MDSCs), which suppress the body’s immune system.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Previous research, including pioneering work at TGen, has shown that glioblastoma occurs at a rate 60 percent higher in males than in females. And, females have a significant survival advantage over males with a median improved survival of up to 10 months. However, while these sex differences are known, they are poorly understood and are not yet considered when treating glioblastoma.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Glioblastomas are aggressive and rare: fewer than 4 per 100,000 in the U.S. from 2012-16, according to the most recent data available from the<span> </span><a href="https://cbtrus.org/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);text-decoration:none;outline:0px !important;" target="_blank">Central Brain Tumor Registry</a><span> </span>of the United States (CBTRUS). The median survival time is 12 to 14 months, and only about 5% of patients survive more than five years.   </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);"> <strong style="box-sizing:border-box;border-radius:0px;font-weight:700;">Leaders of the study</strong> </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">The research team is led by co-principal investigators Justin Lathia, Ph.D., of Cleveland Clinic’s Lerner Research Institute, and Jill Barnholtz-Sloan, Ph.D., of Case Western Reserve University School of Medicine.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">“We have the molecular profiling technology and the computing and analytical strength to lead in this effort to better understand the role of sex differences in cancer, particularly for glioblastoma,” said Dr.<span> </span><a href="https://case.edu/cancer/members/member-directory/jill-s-barnholtz-sloan" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);text-decoration:none;outline:0px !important;" target="_blank">Barnholtz-Sloan</a>, the Sally S. Morley Designated Professor in Brain Tumor Research and associate director of Data Sciences at the Case Comprehensive Cancer Center, Case Western Reserve School of Medicine.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">“This next phase of research relies on vast, varied, and complex datasets — in animals and humans — and promises to be a game-changer in how we understand the role of sex in tumor formation and disease outcomes. This comprehensive approach has applications to all forms of cancer, as well as other diseases,” Dr. Barnholtz-Sloan said.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Dr.<span> </span><a href="https://www.lerner.ccf.org/cms/lathia/" style="box-sizing:border-box;border-radius:0px;background-color:transparent;color:rgb(12, 72, 135);text-decoration:none;outline:0px !important;" target="_blank">Lathia</a><span> </span>is the vice chair of the Department of Cardiovascular and Metabolic Sciences and co-director of the Brain Tumor Research & Therapeutic Development Center of Excellence at Lerner Research Institute, and co-leader of the Molecular Oncology Program at the Case Comprehensive Cancer Center.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">“Sex differences are inherent drivers of glioblastoma incidence and survival and we are taking a multidimensional approach to uncover a better understanding of this differentiation,” Dr. Lathia said. “We are incorporating data from tumor cells and their surrounding micro-environment, as well as genetic programs responsible for tumor growth, and underlying epigenetic differences that may be responsible for sex differences. We aim to gain a better understanding of how these variables interrelate to better understand disease mechanism, which in turn defines better diagnostics and more personalized therapies for patients.”</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">The multi-disciplinary project involves established investigators with complementary expertise and a strong collaborative history. Along with Dr. Lathia and Dr. Barnholtz-Sloan, participating principal investigators include: Dr. Berens of TGen; Joshua Rubin, M.D., Ph.D. of<span> </span><span style="box-sizing:border-box;border-radius:0px;">Washington University School of Medicine in St. Louis</span>; and James Connor, Ph.D., of Penn State College of Medicine.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">The study’s three related research projects will delve into the basic biology and cellular mechanisms that drive sex differences in glioblastoma formation and progression. These related research projects will inform, synergize and depend on each other. Findings from the labs based on their animal models will then be queried against data from human clinical samples across multiple institutions. The vast amount of data generated from these studies requires robust data management and sophisticated data analysis for a comprehensive view of sex differences across these diverse but related inquiries.</p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">Comprehensive findings will inform future clinical research design, the search for targets for new therapeutics, or the use of existing therapeutics that may be applied differently depending on a patient’s sex.   </p> <p style="box-sizing:border-box;border-radius:0px;margin:0px 0px 20px;color:rgb(85, 85, 85);">This NCI grant —<span> </span><em style="box-sizing:border-box;border-radius:0px;">Sex-based Differences in Glioma</em><span> </span>— was awarded under number 1P01CA245705.</p> </div> </div> <br> <br> </h4> <p> <br> </p> </html></div>https://biomedicalphoenix.com/Lists/News/Attachments/82/dr_michael_berens.jpg2020-09-17T07:00:00ZTGen
Women in Medicine Fighting COVID-19: Denege Ward-Wright, MDWomen in Medicine Fighting COVID-19: Denege Ward-Wright, MD<div class="ExternalClass2BBCC94ADDF24203A1E00A742FAF37DA"><html> <div style="box-sizing:border-box;color:rgb(96, 96, 96);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-size:16px;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="field field--name-field-news-media-contact-ref field--type-entity-reference field--label-hidden field__item"><article class="node node--type-media-contact node--promoted node--view-mode-default" role="article" style="box-sizing:border-box;display:block;"><div style="margin-bottom:1.5rem !important;display:flex;box-sizing:border-box;flex-wrap:nowrap !important;align-items:center !important;" class="d-flex flex-nowrap align-items-center mb-4"> <h5 style="box-sizing:border-box;margin-top:0px;margin-bottom:0px !important;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:normal;line-height:18px;color:rgb(155, 155, 155);font-size:15px;margin-right:0.5rem !important;text-transform:uppercase !important;" class="field_title text-uppercase mb-0 mr-2"><span style="box-sizing:border-box;" class="field field--name-title field--type-string field--label-hidden">TERESA JOSEPH</span> </h5> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <a target="_blank" href="https://twitter.com/uazmedphx/" style="box-sizing:border-box;background-color:transparent;color:rgb(1, 28, 72);text-decoration:none;" class="field_media_contact_twitter_url"> <em></em> </a> </h4> </div> </article> </div> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <div style="box-sizing:border-box;margin-bottom:1rem !important;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;color:rgb(33, 33, 33) !important;font-size:1.25rem;font-style:normal;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="field field--name-field-subtitle field--type-string field--label-hidden h5 mb-lg-3 text-dark field__item">Hospitalist Helped Develop Inpatient COVID Tele-Visits to Reduce Physician Exposure</div> </h4> <div style="box-sizing:border-box;color:rgb(96, 96, 96);font-size:17px;line-height:23px;margin-bottom:3rem;padding-bottom:1rem;border-bottom:1px solid rgb(96, 96, 96);font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"> <em>In honor of this year’s <a target="_blank" href="https://phoenixmed.arizona.edu/diversity/wims" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;">Women in Medicine and Science</a> month, the University of Arizona College of Medicine – Phoenix has asked a few faculty to share their inspiring stories and work that is helping our community through the <a target="_blank" href="https://phoenixmed.arizona.edu/covid-19" style="box-sizing:border-box;background-color:transparent;color:rgb(171, 5, 32);text-decoration:underline;transition:all 0.3s ease 0s;">coronavirus pandemic</a>.</em> </p> </h4> <h2 style="box-sizing:border-box;margin-top:0px;margin-bottom:0.5rem;font-family:miloweb, -apple-system, blinkmacsystemfont, "segoe ui", roboto, "helvetica neue", arial, "noto sans", sans-serif, "apple color emoji", "segoe ui emoji", "segoe ui symbol", "noto color emoji";font-weight:700;line-height:1.2;color:rgb(30, 82, 136);font-size:2.1875rem;"> <figure class="bg-light figure img-fluid align-right" role="group" style="box-sizing:border-box;display:inline-block;margin:0px 0px 1rem 1rem;float:right;max-width:0px;height:auto;background-color:rgb(232, 237, 243) !important;"> <div style="box-sizing:border-box;margin-bottom:0.5rem;line-height:1;" class="figure-img"> <img data-entity-type="file" data-entity-uuid="01f5a41d-2f5b-4a42-9598-a99d6480d4ed" src="https://phoenixmed.arizona.edu/sites/default/files/inline-images/wright-story.jpg" alt="Denege Ward-Wright, MD" style="margin:5px;border:0px;width:0px;vertical-align:middle;max-width:100%;box-sizing:border-box;" class="img-fluid" title="Denege Ward-Wright, MD" /> </div> <figcaption class="figure-caption mb-1 px-2 text-right" style="box-sizing:border-box;display:block;font-size:14px;color:rgb(96, 96, 96);margin-bottom:0.25rem !important;padding-right:0.5rem !important;padding-left:0.5rem !important;text-align:right !important;line-height:20px;"> <em style="box-sizing:border-box;">Denege Ward-Wright, MD</em> </figcaption> </figure>Denege Ward-Wright, MD</h2> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">During the pandemic, Denege Ward-Wright, MD, has led the way in helping the hospital set-up telehealth and video conferences for inpatient COVID cases, which is designed to decrease physician exposure while still providing quality patient care.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Dr. Ward-Wright is a clinical associate professor in the Division of Hospital Medicine at the University of Arizona College of Medicine – Phoenix. She has been affiliated with the medical school since 2018.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"> <strong style="box-sizing:border-box;font-weight:bolder;">Describe your experience working during the pandemic</strong> </p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Personally, I have been practicing for about 30 years and during my residency, HIV and AIDS were just being discovered and treated. So, I was experienced in managing patients with unknown pathology and disease process, as well as the anxiety it brings for patients and health care workers treating patients with high rates of fatality and little known treatment options. As an attending in internal medicine, I was also treating patients during the H1N1 pandemic, the threat of SARS-COV1 and MERS possible pandemics and then most recently preparing for the possible Ebola pandemic that fortunately did not materialize.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">I had some anxiety and fear during those times, but I think my curiosity for infectious disease and treating patients superseded my fears. I’ve learned that you must respect diseases and take the most appropriate precautions to mitigate infections and to follow the science. During this pandemic with COVID-19, I was fortunate to have expert pulmonologists, infectious disease specialists and cardiologists who supported and educated the hospitalist in management. Our hospitalist teams were organized and we disseminated information in a controlled and precise manner to alleviate misinformation and help develop standards of care and algorithms for this population of patients. There was daily support in our management. The most amazing experience is working with nurses, nurse practitioners, physician assistants, dieticians, clerks and environmental services who worked with these patients and provided 24-hour care with no visible anxiety and comforted these patients daily.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Working with COVID-19 patients has helped me accept the mitigation practices all of us need to take to prevent the spread. The constant politicizing of this disease has made it difficult as there are still some patients and families that cannot accept the measures needed to ensure public safety and that has also been challenging.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"> <strong style="box-sizing:border-box;font-weight:bolder;">What advice or words of encouragement do you have for other physicians during this time of uncertainty?</strong> </p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Paying attention to the science and public health policies is a pathway of understanding, and that is helpful in trying to protect each other’s safety. I think if we respect this disease and accept that lifestyles have changed then it helps to move forward. Try to look at the positives that have come out of this, prioritizing what is important in our happiness such as the closeness that we developed or rediscovered in our families and communities. Also, to be mindful of our feelings and take steps to our own wellness — whether it be reading, exercising, listening to music or tapping in to whatever creative talents you may have.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"> <strong style="box-sizing:border-box;font-weight:bolder;">What would you like the community to know about your work during this time as a woman in medicine and science?</strong> </p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">I feel anxious at times; I am sometimes fearful of what the future may bring. However, paying attention to how patients have recovered and watching the trends improve in our cities and states brings about promise. I think women in medicine are mothers and daughters and have the same concerns for their family and communities. Also, we follow the science and public health experts to deliver the best care possible.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"> <strong style="box-sizing:border-box;font-weight:bolder;">What does your day-to-day look like right now?</strong> </p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Usually, I begin my day earlier to review charts and before I do my rounds, I put on all my PPE and see my patients. Not much has changed in my rounding with patients. I’ve gotten used to talking through masks and a face shield, and I notice patients have, as well. This pandemic has made it to where I can no longer give a patient a hug. I also find myself no longer going back and forth to the patient rooms as much as before to limit exposure.</p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;"> <strong style="box-sizing:border-box;font-weight:bolder;">Can you describe the inpatient telehealth system you helped set-up?</strong> </p> <p style="box-sizing:border-box;margin-top:0px;margin-bottom:1rem;">Banner has been using telehealth in the ambulatory setting to facilitate patient appointments. In the inpatient setting, we have some designated rooms where there is a camera attached to the TV and physicians can communicate with those patients who are able through a secure program at a hospital workstation or website for a tele-visit. This currently operates only while in the hospital with the goal to limit exposure to COVID positive patients. It has limitations, as the patient needs to be able to communicate and is only present in designated rooms.</p> </h4> </div> <h4 class="n_gEPV1NTWQkXX0HDg_0 ap_gEPV1NTWQkXX0HDg_0 inheritFontFamily"> <br>​<br></h4> <p> <br> </p> </html></div>2020-09-16T07:00:00ZUA
Ashion Analytics announces innovative cancer treatment partnership with Elevation OncologyAshion Analytics announces innovative cancer treatment partnership with Elevation Oncology<div class="ExternalClassDA589023AF34469082BC9DF9D4102CB6"><html> <p></p><span id="ms-rterangepaste-start"></span><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;"><span style="box-sizing:border-box;" class="xn-location">PHOENIX</span>,<span> </span><span style="box-sizing:border-box;" class="xn-chron">Sept. 16, 2020</span><span> </span>/PRNewswire/ -- <a rel="nofollow" target="_blank" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">Ashion Analytics LLC</a><span> </span>today announced a partnership with<span> </span><span style="text-decoration:underline;"><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=2236143105&u=http://www.elevationoncology.com/&a=Elevation+Oncology" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">Elevation Oncology</a></span>, a clinical stage biopharmaceutical company, focused on the matching of patients with tumors harboring an NRG1 gene fusion identified using Ashion's proprietary GEM ExTra® test with CRESTONE, a registration-directed Phase 2 study sponsored by Elevation Oncology.</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;">NRG1 gene fusions are a rare genomic alteration implicated as a driver of tumorigenesis and growth across many types of solid tumors, including lung, breast, pancreatic, ovarian, and colorectal cancers.<span> </span><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=2157809113&u=https://nrg1fusion.com/&a=CRESTONE" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">CRESTONE</a><span> </span>— or<span> </span><span style="text-decoration:underline;">C</span>linical study of<span> </span><span style="text-decoration:underline;">RE</span>sponse to<span> </span><span style="text-decoration:underline;">S</span>eribantumab in<span> </span><span style="text-decoration:underline;">T</span>um<span style="text-decoration:underline;">O</span>rs with<span> </span><span style="text-decoration:underline;">NE</span>uregulin 1 (NRG1) fusions — provides an investigational treatment opportunity for patients with any advanced solid tumor who have not responded or are no longer responding to standard cancer treatment, and whose tumor has tested positive for an<span> </span><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=802101388&u=https://nrg1fusion.com/wp-content/uploads/2020/07/EO0003-001-000_NRG1-fusion-1-pager.pdf&a=NRG1" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">NRG1</a><span> </span>fusion.</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;">This partnership creates a new dynamic in the way cancer patients can be matched to precision medicine therapeutics. By first identifying a genetic driver that has an available targeted therapy option, in this case an NRG1 fusion and the investigational therapy seribantumab, the diagnostic technology, data insights, and network reach at Ashion Analytics can be leveraged to efficiently identify and directly match eligible patients to the CRESTONE trial using test results that are already available today, while also maximizing the value of every additional test.</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;">"The comprehensive nature of the GEM ExTra test means that its value grows directly with each new genomic driver that is identified and each new precision therapy under development," said<span> </span><span style="box-sizing:border-box;" class="xn-person">Laurie Goodman</span>, Ph.D., Ashion Analytics Director of Business Development and Medical Affairs. "Partnerships like this enable us to continuously facilitate the ability for our patients to receive the most up-to-date information about the emerging treatment opportunities available to them today."</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;"><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=862518699&u=https://www.tgen.org/news/2020/july/14/medicare-covers-tgen-ashions-gem-extra-cancer-test/&a=Ashion+Analytics+recently+announced" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">Ashion Analytics recently announced</a><span> </span>that Medicare has approved coverage of its proprietary cancer profiling test,<span> </span><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=638858039&u=http://ashion.com/physicians-2/&a=GEM+ExTra" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">GEM ExTra</a>®, one of the nation's most comprehensive genomic cancer analysis tests. Medicare coverage enables potentially 44 million more patients to afford this test, which aims to match patients with best available treatments for their disease.</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;"><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=915260637&u=https://www.tgen.org/news/2020/june/11/tgen-s-ashion-certified-for-nci-match/&a=GEM+ExTra" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">GEM ExTra</a><span> </span>detects tumor-specific mutations in both DNA and RNA, allowing physicians to make the best-available treatment recommendations for patients with advanced solid tumors. An Ashion study poster presented at the 2020 annual meeting of the American Society for Clinical Oncology (ASCO) details the importance of using RNA as part of the analysis to give cancer physicians the best possible options for treating their patients: <a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=3353191598&u=https://urldefense.com/v3/__https:/tgen.us10.list-manage.com/track/click?u%3D6b0e128788a10661a1fb2d549%26id%3D80cc45bf65%26e%3Dbcd23e9d1a__%3b%21%21Fou38LsQmgU%215is31ALaqgPXIWwf0RCLxSUwenylXnIgeVfTtWnkZc7oP1oqRiYeOToaeHqm$&a=Employing+RNA+Sequencing+to+Enhance+Treatment+Options+for+Cancer+Patients" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">Employing RNA Sequencing to Enhance Treatment Options for Cancer Patients</a>.</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;">This leading-edge test provides treating physicians with vital interpreted information needed to understand changes to a patient's genomic profile. It outlines a therapeutic treatment plan best suited for each patient. Conditions that may benefit from this approach include treatment of refractory, rare or aggressive cancers.</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;">"We are partnering with Ashion Analytics because we recognize the sensitivity and continuing potential of their GEM ExTra cancer profiling test," said<span> </span><span style="box-sizing:border-box;" class="xn-person">Shawn Leland</span>, PharmD, RPh, Founder and Chief Business Officer of Elevation Oncology. "Elevation Oncology is committed to expanding the benefit of precision medicine to all patients with cancer by developing therapies that make results from tests like GEM ExTra clinically actionable, no matter how rare the finding. Close collaboration between diagnostic and therapeutic developers is critical to re-thinking our approach to clinical trial enrollment as an industry and finding more efficient ways to bring the right treatment opportunities to the patients that need them."</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;">For more information about seribantumab and the CRESTONE study, please visit<span> </span><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=1504483846&u=http://www.nrg1fusion.com/&a=www.NRG1fusion.com" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">www.NRG1fusion.com</a>.</p><p style="box-sizing:border-box;margin:0px 0px 35px;font-size:16px;line-height:1.8;color:rgb(55, 55, 55);font-family:montserrat, helvetica, arial, sans-serif;font-style:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-spacing:0px;background-color:rgb(255, 255, 255);text-decoration-style:initial;text-decoration-color:initial;">Ashion Analytics is a clinical laboratory of the<span> </span><span style="text-decoration:underline;"><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=4084671636&u=https://www.tgen.org/&a=Translational+Genomics+Research+Institute+%28TGen%29" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">Translational Genomics Research Institute (TGen)</a></span>, an affiliate of<span> </span><span style="text-decoration:underline;"><a rel="nofollow" target="_blank" href="https://c212.net/c/link/?t=0&l=en&o=2917086-1&h=4122051859&u=https://www.cityofhope.org/homepage&a=City+of+Hope" style="box-sizing:border-box;background-color:transparent;color:rgb(0, 131, 126);text-decoration:none;word-break:break-word;">City of Hope</a></span>. TGen is a pioneer in the use of genomics to identify treatment options for cancer patients.​<br></p><span id="ms-rterangepaste-end"></span><p>​​<br></p> </html></div>2020-09-16T07:00:00ZAshion Analytics

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